- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Moyamoya disease diagnosis and treatment
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Neurological Complications and Syndromes
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Trigeminal Neuralgia and Treatments
- Cardiac Arrhythmias and Treatments
- Cardiac tumors and thrombi
- Diagnosis and Treatment of Venous Diseases
- Botulinum Toxin and Related Neurological Disorders
- Metabolomics and Mass Spectrometry Studies
- Photoacoustic and Ultrasonic Imaging
- Cardiovascular Issues in Pregnancy
- Spinal Hematomas and Complications
- Cerebrovascular and genetic disorders
- Optical Imaging and Spectroscopy Techniques
- Otolaryngology and Infectious Diseases
- Neurofibromatosis and Schwannoma Cases
- Intracerebral and Subarachnoid Hemorrhage Research
Keio University
2015-2025
Keio University Hospital
2021-2023
Toranomon Hospital
2019-2021
The Tsuruoka Metabolomics Cohort Study (TMCS) is an ongoing population-based cohort study being conducted in the rural area of Yamagata Prefecture, Japan. This aimed to enhance precision prevention multi-factorial, complex diseases, including non-communicable and aging-associated by improving risk stratification prediction measures. At baseline, 11,002 participants aged 35–74 years were recruited City, Japan, between 2012 2015, with follow-up survey. Participants underwent various...
Flow diverters (FDs) have marked the beginning of innovations in endovascular treatment large unruptured intracranial aneurysms, but no multi-institutional studies been conducted on these devices from both clinical and economic perspectives.To compare retreatment rates healthcare expenditures between FDs conventional coiling-based treatments all eligible cases Japan.We identified patients who had undergone during study period (October 2015-March 2018) a national-level claims database. The...
A subgroup analysis of spinal vascular lesions registered in the Japanese Registry Neuroendovascular Therapy 2 (JR-NET2) and JR-NET3 was performed. About 172 analyzable cases dural arteriovenous fistula (SDAVF) were assessed, including characteristics, treatment strategy, outcome. SDAVF more common middle-aged older males. The most commonly affected area thoracolumbosacral region (83.7%), had a non-hemorrhagic onset (89.0%). Complete obliteration achieved 54.7%. Treatment-related...
Some patients develop ischemic stroke despite taking direct oral anticoagulants because of the presence other risk factors such as coagulopathies. A 65-year-old male patient with non-valvular atrial fibrillation (NVAF) rivaroxaban was diagnosed having embolic and antithrombin-III (AT-III) deficiency. Echocardiography revealed a thrombus in left appendage (LAA). He prescribed warfarin, after resolution thrombus, we successfully performed percutaneous LAA closure (LAAC), no subsequent...
Patients with neurofibromatosis type 1 not only have characteristic skin findings but are also known to vascular disorders due vulnerability. A 44-year-old man previously undiagnosed was brought the emergency room a sudden subcutaneous hematoma no history of trauma. Angiography revealed extravasation from parietal branch right superficial temporal artery, which embolized n-butyl-2-cyanoacrylate. However, next day, patient exhibited an increased hematoma, and new extravascular leakage...
Previous reports have suggested that direct oral anticoagulants exert a prothrombolytic effect against intracardiac thrombi. We hypothesized these may also help recanalize occluded intracranial arteries via effects. In this study, we evaluated the effects of rivaroxaban, anticoagulant, on fibrin emboli within cerebrocortical microvessels in mouse model embolic stroke. Fibrin prepared ex vivo were injected into common carotid artery male C57BL/6 mice, and embolization brain surface was...
We occasionally encounter situations which requires retraction of the guiding system or administration vasodilatory agents for mechanically induced vasospasm (MVS). However, whether MVS is associated with postoperative cerebral infarction has not been reported.To explore factors and to verify how influences procedure outcomes,we reviewed consecutive cases unruptured aneurysms in anterior circulation treated coil embolization between January 2017 February 2020. Collected data included...
Cerebral venous thrombosis (CVT) is challenging to diagnose, as it presents with variable symptoms. We encountered a complicated case of CVT that mimicked limbic encephalitis due sensory aphasia. Based on the characteristic magnetic resonance imaging findings, this 72-year-old Japanese man was later confirmed have CVT, cause which periodontitis Eikenella corrodens, Gram-negative facultative anaerobic part mouth's normal flora. The symptoms improved without sequelae following anticoagulation...
More complex aneurysms can be treated by coil embolization with neck-bridge stent assistance. However, concerns about postprocedural ischemic or hemorrhagic complications remain. In this study, we assessed the long-term durability after introduction of in context for unruptured aneurysm comparing re-treatment and neurological events between pre-stent eras. Unruptured April 2005 May 2018 were analyzed retrospectively. We divided cases into two groups: era era. The cumulative rate compared....
Although several studies have reported on cerebral hyperperfusion syndrome (CHS)/hyperperfusion phenomenon (HPP) involving the anterior circulation after carotid artery stenting (CAS), little is known about CHS/HPP posterior percutaneous transluminal angioplasty (PTA) and of vertebral (VA).A 79-year-old man with chronic occlusion left VA (V4 segment) was admitted to another hospital right-sided hemiplegia, mild disturbance consciousness, dysphagia. A head MRI revealed multiple infarcts in...
We report a patient with symptomatic intraluminal internal carotid artery thrombus clinically revealed by cerebral infarction. In the preoperative evaluation, it was that essential thrombocythemia existed in background. Therefore, medical treatment antithrombotic agents conjunction hydroxycarbamide for initiated, but not dissolved three weeks. At this time, underwent endarterectomy, which removed completely its adjacent plaque without any perioperative stroke. The possibility of may also be...
Background To prevent ischemic complications during carotid artery stenting, accurate detection of plaque protrusion and appropriate additional treatment are essential. Here, we introduce a novel method for the under distal balloon protection using three-dimensional rotation angiography—“retrograde 3DRA.” We evaluated safety efficacy this method. Materials methods retrospectively analyzed 28 consecutive stenting procedures at our hospital between July 2017 August 2019. The first line was...
Cerebral hyperperfusion syndrome is a rare but severe complication of carotid artery stenting or endarterectomy. Staged angioplasty reportedly an effective strategy to avoid cerebral syndrome. We encountered case internal stenosis with clinical presentation limb shaking that was successfully improved by staged angioplasty. To our knowledge, there are no reported cases treated angioplasty.A 76-year-old woman presented continuous chorea in her left lower and shoulder. Medical examination...