A5010511231- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Contact Dermatitis and Allergies
- Skin Protection and Aging
- Advancements in Transdermal Drug Delivery
- Acute Myeloid Leukemia Research
- melanin and skin pigmentation
- Occupational exposure and asthma
- Food Allergy and Anaphylaxis Research
- Immune Cell Function and Interaction
- Dermatologic Treatments and Research
- Acne and Rosacea Treatments and Effects
- Nail Diseases and Treatments
- Asthma and respiratory diseases
- Chronic Myeloid Leukemia Treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Autoimmune Bullous Skin Diseases
- Exercise and Physiological Responses
- Respiratory viral infections research
- Urticaria and Related Conditions
- Bacteriophages and microbial interactions
- Traditional Chinese Medicine Studies
- Dental Implant Techniques and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Microwave Dielectric Ceramics Synthesis
First Affiliated Hospital of Fujian Medical University
2021-2025
Fujian Medical University
2021-2025
Beijing Children’s Hospital
2025
Capital Medical University
2025
Shanghai Skin Disease Hospital
2015-2024
Tongji University
2010-2024
Hunan Provincial Maternal and Child Health Hospital
2022-2024
Shantou University
2024
China Three Gorges University
2018-2023
Anhui University of Finance and Economics
2023
Background Bullous pemphigoid (BP) is an autoimmune blistering disorder that predominantly affects the elderly. As main treatment for BP, systemic corticosteroids are often limited by their side effects. Safer modalities therefore needed. Dupilumab a biologic agent used to treat BP in recent years. Methods Medical records of patients with moderate-to-severe were retrospectively reviewed. Twenty-four included (follow-up period: 32 weeks), eight whom received dupilumab combination...
Abstract Background The prevalence of mitochondrial diseases is increasing, leading to a significant economic burden on families and society. However, nationwide cost data their effects China’s economy remain limited. This study aimed investigate the in Chinese children, analyse relevant influencing factors, provide foundation for strategies reduce healthcare burden. Methods In this single-centre, cross-sectional study, an online questionnaire was randomly administered paediatric patients...
Non-optimum weather conditions and air pollution have the potential to increase risk of atopic dermatitis (AD), but associations are rarely evaluated, especially in developing countries.To investigate independent influence interaction effects meteorological factors pollutants on onset AD.Daily data outpatient visits AD were obtained from Shanghai Dermatology Hospital comprised 34,633 patients during period January 2013 December 2018. Meteorological pollutant concentrations Shanghai, China,...
Abstract Atopic dermatitis (AD) is a common disease clinically characterized by chronic recurrent eczematous lesions, dry skin, and pruritus. AD can negatively impact patients’ quality of life. The prevalence in China has been increasing during the past few decades. Based on most recent advances treatment AD, we updated 2014 version Guidelines for Diagnosis Treatment Dermatitis regarding definition, epidemiology, pathogenesis, clinical classification, diagnosis, prevention, AD.
Allergic respiratory diseases have increased dramatically due to air pollution over the past few decades. However, studies are limited on effects of inorganic components and particulate matter with different particle sizes in smog allergic diseases, possible molecular mechanism inducing allergies has not been thoroughly studied.Four common mineral elements particles were selected, including Al2O3, TiO2, Fe2O3, SiO2. We studied relationship composition, size, reactions using mast cells,...
Abstract Background Noninvasive energy‐based device (NI‐EBD) aesthetic procedures has recently gained widespread usage for treating various skin conditions, enhancing texture and performing rejuvenation‐related procedures. However, practically all NI‐EBD result in variable degrees of damage to the barrier, inducing pathological physiological processes such as oxidative stress inflammation, only a small percentage individuals possess innate ability restore it. Objective To introduce concept...
This study evaluated the effects of three vehicles—ethanol (EtOH), isopropyl alcohol (IPA), and myristate (IPM)—on stratum corneum (SC) absorption diffusion [ 14 C]-model compounds benzoic acid butenafine hydrochloride to better understand transport pathways chemicals passing through resident in SC. Following application topical formulations human dermatomed skin for 30 min, penetration flux was observed 24 h post dosing, using an vitro flow-through system. Skin compared chemical-SC (intact,...
As part of plans to provide help people in remote and poor areas who have no medical resources, a portable slit-lamp based on smartphone was proposed. This would early screening cataract diseases.This means microlens is designed that work with phone's camera. The photo taking function used capturing the image eyes lens replace observation system desktop slit-lamp. A simplified slit light band designed. In order for source meet requirements slit-lamp, adjustable diffused functions ligaments...
With rapid development of nanotechnology, there is increasing interest in nanoparticle (NP) application and its safety efficacy on human skin. In this study, we utilized confocal laser scanning microscopy to estimate NP skin penetration.Three different-sized polystyrene NPs marked with red fluorescence were applied skin, Calcium Green 5N was used as a counterstain. Dimethyl sulfoxide (DMSO) ethanol alternative vehicles for NPs. Tape stripping barrier-damaged model. Skin biopsies dosed...
Background Different wavelengths of ultraviolet (UV) light cause skin damage through different mechanisms. Minimal erythema dose (MED) is usually used to clinically evaluate sensitivity radiation by inducing using B (UVB) or A (UVA) + UVB. Aims In this study, we detected changes in the blood flow at MED caused UVB and UVA optical coherence tomography (OCT) explain role bands rays induction. Methods Two irradiation areas on subjects' back were irradiated with alone (UVA: = 8:1). The absolute...
Atopic dermatitis (AD) is a common and chronic inflammatory skin disease that erupts periodically. Although the negative impact of disorder on overall quality life has been well established, new treatments for AD are still needed. Various studies have reported cannabidiol's effectiveness in relieving pain easing inflammation while not presenting major health risks. In this communication, we aim to demonstrate novel cannabidiol (CBD) aspartame formulation, JW-100, signs symptoms AD. We...
Laser treatment of acne scars is common, but quality evidence on its efficacy still needed. Our study aimed to compare picosecond laser and non-ablative fractional laser's safety in treating atrophic scars.This was a randomized, split-face double-blind trial recruiting patients with scars. Facial halves were randomly divided treated fractionated frequency-doubled 1,064/532 nm Nd:YAG or 1,540 Er: glass laser. ECCA score (echelle d'evaluation clinique des cicatrices d'acne) skin flatness...
The Dicer and Argonaute(AGO) proteins within the small RNA regulatory pathways (SRRPs) play an indispensable role in regulation of gene expression. In this study, we analyzed two genes, Argonaute, from Schistosoma japonicum, along with their expression through a combination bioinformatics experimental approaches.Our results indicate that one four Argonaute genes exist termed SjDicer SjAGO1, 2, 3, 4, respectively. encodes 2590 amino acid residues contains 5 conserved domains, including...