Yoshie Yokoyama
- Assisted Reproductive Technology and Twin Pregnancy
- Birth, Development, and Health
- Obesity, Physical Activity, Diet
- Cognitive Abilities and Testing
- Pregnancy and preeclampsia studies
- Prenatal Screening and Diagnostics
- Genetic Associations and Epidemiology
- Breastfeeding Practices and Influences
- Homicide, Infanticide, and Child Abuse
- Infant Development and Preterm Care
- Demographic Trends and Gender Preferences
- Child Nutrition and Feeding Issues
- Maternal Mental Health During Pregnancy and Postpartum
- Family Support in Illness
- Synthesis and Catalytic Reactions
- Psychosocial Factors Impacting Youth
- Nutrition, Genetics, and Disease
- Chemical Synthesis and Analysis
- Ectopic Pregnancy Diagnosis and Management
- Neonatal Respiratory Health Research
- Health and Wellbeing Research
- Nutritional Studies and Diet
- Child Abuse and Trauma
- Click Chemistry and Applications
- Genetic and phenotypic traits in livestock
Osaka Metropolitan University
2022-2024
Osaka City University
2013-2022
Osaka City University Hospital
2017
Okayama University
1989-2007
Kyoto University
2001-2004
Kyoto College of Medical Science
2002-2003
RMIT University
2003
Shiga University of Medical Science
1999
Kindai University
1995-1997
Hokuriku University
1996
Abstract Height variation is known to be determined by both genetic and environmental factors, but a systematic description of how their influences differ sex, age global regions lacking. We conducted an individual-based pooled analysis 45 twin cohorts from 20 countries, including 180,520 paired measurements at ages 1–19 years. The proportion height explained shared factors was greatest in early childhood, these effects remained present until adulthood. Accordingly, the relative contribution...
Abstract We investigated the heritability of educational attainment and how it differed between birth cohorts cultural–geographic regions. A classical twin design was applied to pooled data from 28 representing 16 countries including 193,518 twins with information on at 25 years age or older. Genetic factors explained major part individual differences in (heritability: a 2 = 0.43; 0.41–0.44), but also environmental variation shared by co-twins substantial (c 0.31; 0.30–0.33). The proportions...
Twins and triplets are at higher risk of cerebral palsy than singletons. This study investigated the degree for in twins, quadruplets, identified factors associated with increased risk. The subjects were recruited from Kinki University Twin Higher Order Multiple Births Registry. 705 twins pairs (1410 twins), 96 sets (287 excluding one infant death), 7 quadruplets (27 who born after 1977. prevalence was 0.9% among 1410 3.1% 287 triplets, 11.1% 27 quadruplets. Furthermore, risks producing...
For over 100 years, the genetics of human anthropometric traits has attracted scientific interest. In particular, height and body mass index (BMI, calculated as kg/m 2 ) have been under intensive genetic research. However, it is still largely unknown whether how heritability estimates vary between populations. Opportunities to address this question increased recently because establishment many new twin cohorts increasing accumulation data in established cohorts. We started a research project...
Human height variation is determined by genetic and environmental factors, but it remains unclear whether their influences differ across birth-year cohorts. We conducted an individual-based pooled analysis of 40 twin cohorts including 143,390 complete pairs born 1886–1994. Although variance showed a generally increasing trend the cohorts, heritability estimates (0.69-0.84 in men 0.53-0.78 women) did not present any clear pattern secular changes. Comparing geographic-cultural regions (Europe,...
Objective The objective of this study was to analyze how parental education modifies the genetic and environmental variances BMI from infancy old age in three geographic‐cultural regions. Methods A pooled sample 29 cohorts including 143,499 twin individuals with information on 1 79 years (299,201 measures) analyzed by modeling. Results Until 4 age, not consistently associated BMI. Thereafter, higher level lower males females. Total additive were smaller offspring highly educated parents than...
Abstract Background Body mass index (BMI) shows strong continuity over childhood and adolescence high BMI is the strongest predictor of adult obesity. Genetic factors strongly contribute to this continuity, but it still poorly known how their contribution changes adolescence. Thus, we used genetic twin design estimate correlations from infancy adulthood compared them height. Methods We pooled individual level data 25 longitudinal cohorts including 38,530 complete pairs having 283,766 height...
Genetic factors explain a major proportion of human height variation, but differences in mean stature have also been found between socio-economic categories suggesting possible effect environment. By utilizing classical twin design which allows decomposing the variation into genetic and environmental components, we tested hypothesis that is greater offspring lower educated parents. Twin data from 29 cohorts including 65,978 complete pairs with information on at ages 1 to 69 years parental...
Abstract This study investigated the degree of risk handicap in twins, triplets, quadruplets and quintuplets associated factors, examined clustering tendency handicaps. The sample was recruited from Kinki University Twin Higher Order Multiple Birth Registry. panel consisted 705 pairs twins (1410 twins), 96 sets triplets (287 excluding 1 infant death), 7 (27 2 (10 quintuplets), all whom were born after 1977. incidence 3.7% 8.7% 11.1% quadruplets, 10.0% quintuplets. prodicing at least...
There is evidence that birth size positively associated with height in later life, but it remains unclear whether this explained by genetic factors or the intrauterine environment. To analyze associations of weight, length and ponderal index from infancy through adulthood within mono- dizygotic twin pairs, which provides insights into role environmental individual-specific factors. This study based on data 28 cohorts 17 countries. The pooled included 41,852 complete pairs (55% monozygotic...
Abstract This study was performed to determine the rates of breastfeeding among singletons, twins and triplets in Japan, identify factors associated with decision breastfeed or bottle-feed. We analyzed a database medical check-up infants aged 3 6 months between April 2001 July 2004 Nishinomiya City Japan. is given almost 100% Japan data 15,262 were analyzed. Among these, 14,963 (98.0%) 290 (1.9%) 9 (0.1%) triplets. Exclusive breast-feeding chosen by 6680 (43.8%) mothers, mixed-feeding 4645...
This study was performed to determine the rates of breastfeeding among singletons, twins and triplets in Japan, identify factors associated with decision breastfeed or bottle-feed. We analyzed a database medical check-up infants aged 3 6 months between April 2001 July 2004 Nishinomiya City Japan. is given almost 100% Japan data 15,262 were analyzed. Among these, 14,963 (98.0%) 290 (1.9%) 9 (0.1%) triplets. Exclusive breast-feeding chosen by 6680 (43.8%) mothers, mixed-feeding 4645 (30.4%)...
Abstract Objective This study aimed to elucidate the actual activities conducted by public health nurses during their dispatch and status after three prefectures most severely affected Great East Japan Earthquake. Sample A survey request was sent a total of 2,237 facilities. Of these, 778 facilities returned questionnaires from dispatched nurses. Results The participants this were 1,570 who participated in mostly at evacuation centers, followed evacuees’ homes. After dispatch, an earlier...
A trend toward greater body size in dizygotic (DZ) than monozygotic (MZ) twins has been suggested by some but not all studies, and this difference may also vary age. We analyzed zygosity differences mean values variances of height mass index (BMI) among male female from infancy to old Data were derived an international database 54 twin cohorts participating the COllaborative project Development Anthropometrical measures Twins (CODATwins), included 842,951 BMI measurements aged 1 102 years....
Abstract The COllaborative project of Development Anthropometrical measures in Twins (CODATwins) is a large international collaborative effort to analyze individual-level phenotype data from twins multiple cohorts different environments. main objective study factors that modify genetic and environmental variation height, body mass index (BMI, kg/m 2 ) size at birth, additionally address other research questions such as long-term consequences birth size. started 2013 open all twin projects...
There is evidence that birthweight positively associated with body mass index (BMI) in later life, but it remains unclear whether this explained by genetic factors or the intrauterine environment. We analysed association between and BMI from infancy to adulthood within twin pairs, which provides insights into role of environmental individual-specific factors.This study based on data 27 cohorts 17 countries. The pooled included 78 642 individuals (20 635 monozygotic 18 686 same-sex dizygotic...
The genetic architecture of birth size may differ geographically and over time. We examined differences in the environmental contributions to birthweight, length ponderal index (PI) across geographical-cultural regions (Europe, North America Australia, East Asia) cohorts, how gestational age modifies these effects.Data from 26 twin cohorts 16 countries including 57 613 monozygotic dizygotic pairs were pooled. Genetic variations estimated using structural equation modelling.The variance...
It is well established that boys are born heavier and longer than girls, but it remains unclear whether birth size in twins affected by the sex of their co-twin. We conducted an individual-based pooled analysis 21 twin cohorts 15 countries derived from COllaborative project Development Anthropometrical measures Twins (CODATwins), including 67,850 dizygotic individuals. Linear regression analyses showed having a co-twin sister were, on average, 31 g (95% CI 18 to 45) 0.16 cm 0.045 0.274)...
We analyzed birth order differences in means and variances of height body mass index (BMI) monozygotic (MZ) dizygotic (DZ) twins from infancy to old age. The data were derived the international CODATwins database. total number BMI measures 0.5 79.5 years age was 397,466. As expected, first-born had greater weight than second-born twins. With respect height, slightly taller childhood. After adjusting results for weight, decreased no longer statistically significant. First-born over childhood...
Significance Low birthweight is a risk factor for developmental delay, and also associated with higher odds of being left-handed. Likewise, compared singletons, triplet births encompass an increased probability left-handedness delay. In large study, including triplets from two countries, we studied if postnatal development. Triplets have naturally low birthweights, about 1.5 kg lighter than singletons. both samples triplets, showed that was lower birthweight. Left-handers had smaller infant...
BACKGROUND: The purpose of this study was to analyze the characteristics physical growth twins in childhood and present charts Japanese twins.METHODS: subjects consisted 2029 pairs normally developed twins. Growth data were obtained by mailed or hand-distributed questionnaires. Factors that affect body weight height/length at selected ages analyzed stepwise regression analysis. Selected percentiles weight, height/length, mass index calculated according sex, curves drawn using a spline...