A5073775439- Animal Nutrition and Physiology
- Meat and Animal Product Quality
- Immune cells in cancer
- Aquaculture Nutrition and Growth
- Immune Cell Function and Interaction
- Birth, Development, and Health
- Livestock and Poultry Management
- Atherosclerosis and Cardiovascular Diseases
- Chronic Lymphocytic Leukemia Research
- Animal and Plant Science Education
- Probiotics and Fermented Foods
- Bee Products Chemical Analysis
- Insect Utilization and Effects
- Animal Behavior and Welfare Studies
- Insect and Arachnid Ecology and Behavior
- Rabbits: Nutrition, Reproduction, Health
- Microbial Metabolites in Food Biotechnology
- Immunotherapy and Immune Responses
- Food and Agricultural Sciences
- Paraquat toxicity studies and treatments
- Hydrogen's biological and therapeutic effects
- Epigenetics and DNA Methylation
- Protein Interaction Studies and Fluorescence Analysis
- Essential Oils and Antimicrobial Activity
- Pesticide and Herbicide Environmental Studies
Dankook University
2018-2025
Air Force Medical University
2021-2025
Xijing Hospital
2021-2025
Capital University of Physical Education and Sports
2025
Dalian Minzu University
2025
Dana-Farber Cancer Institute
2024
Huazhong Agricultural University
2024
Northeast Agricultural University
2020-2024
Liaocheng University
2024
Sichuan University
2024
Autoimmune diseases such as ankylosing spondylitis (AS) can be driven by emerging neoantigens that disrupt immune tolerance. Here, we developed a workflow to profile posttranslational modifications involved in neoantigen formation. Using mass spectrometry, identified panel of cysteine residues differentially modified carboxyethylation required 3-hydroxypropionic acid generate patients with AS. The lysosomal degradation integrin αIIb [ITGA2B (CD41)] carboxyethylated at Cys96 (ITGA2B-ceC96)...
This research investigates the role of inhibitor differentiation 2 (Id2) in synthesis pro-inflammatory cytokines, specifically interferon-γ (IFN-γ) and interleukin-17 (IL-17), by various subsets T cells, its pathogenic rheumatoid arthritis (RA). Flow cytometry was employed to assess T-cell activation Id2 expression 72 RA patients 23 healthy controls. In vitro, peripheral blood mononuclear cells were treated with either an or a co-stimulation inhibitor. An vivo collagen-induced (CIA) model...
This study was conducted to evaluate the effects of feeding fermented wheat bran (FWB) and yeast culture (YC) on growth performance, immune levels, intestinal microflora in growing-finishing pigs. In total, 96 crossbred pigs were randomly distributed into four treatments with replicates pens six per pen. performed using a 2 × factor design: 1) CON (basal diet), 2) FWB diet + 5% FWB), 3) YC 2% YC), 4) YC). Dietary supplementation significantly increased average daily gain decreased feed ratio...
Objectives This study aimed to investigate the changes in quantity and function of T helper (Th)-like regulatory (Treg) cell subsets peripheral blood (PB) synovial fluid (SF) rheumatoid arthritis (RA) patients understand their relationship with disease activity. Methods A total 86 RA 76 gender age-matched healthy controls (HC) were enrolled this study. Th-like Treg frequency determined using flow cytometry. The inhibitory cells was detected an vitro co-culture suppression assay. Results...
Glyphosate-based herbicides (GBHs) are the most widely used pesticide worldwide and can provoke placental injury. However, whether how GBHs damage angiogenesis in placenta is not yet known. This work evaluated safety of glyphosate on pregnant sows based limit level by governments investigated effects mechanism Low-GBHs (20 mg/kg) High-GBHs (100 exposure angiogenesis. Results showed that gestational to decreased vessel density cell multiplication interfering with expression VEGFA, PLGF,...
This study aimed to investigate the effects of different defatting methods black soldier fly (Hermetia illucens) larvae meal (BSFM) on metabolic energy and nutrient digestibility in laying hens. Sixty young hens (Hy-Line W-36) aged 63 days were randomly divided into two groups (G1 G2), each with five replicates six housed individual cages. Group G1 was fed 25% pressed (BSFMp) 75% basal diet, G2 extracted (BSFMe) a diet. Both diets included 5 g/kg chromium oxide as an external marker. A 7-day...
ABSTRACT This study was conducted to investigate the effect of diets with different metabolizable energy (ME) levels on broiler growth performance, nutrient digestibility, fecal score, organ weight and lesion score. A total 1134 1‐day‐old Ross chicks an initial body (BW) 44.33 ± 1.70 g were randomly assigned three dietary treatment groups. There 21 replicate pens per treatment, including 18 male birds pen. The experimental period divided into 3 phases provided broilers from days 1 34 age:...
To investigate the association between preschool children's 24-h movement behaviors and health-related quality of life (HRQoL), exploring impact time reallocation among these examining gender differences. This study analysed HRQoL 349 children in three kindergartens Beijing, China, selected through convenience sampling using a cross-sectional design. A t-test multivariate analysis variance methods were used to The examined relationship component data isochronic substitution model methods,...
Vascular restenosis is a serious clinical issue initiated and aggravated by macrophage inflammation, with no effective treatments available, in cardiovascular autoimmune diseases. However, the untapped mechanisms new targets that can regulate polarization vascular remain elusive. The research identifies interferon regulatory factor 4 (IRF4) expression as crucial during arterial restenosis. Myeloid-specific Irf4 deficiency overexpression experiments showed IRF4 promoted M2 polarization,...
Fusobacterium nucleatum is strongly linked to colorectal cancer (CRC) progression, but its mechanisms for influencing macrophage polarization and tumor development are not well understood. We established an in vitro model of F. infection RAW264.7 macrophages investigate these processes. Macrophage was evaluated using scanning electron microscopy (SEM), real-time quantitative PCR (RT-qPCR), immunofluorescence staining. RNA sequencing (RNA-Seq) identified differentially expressed genes (DEGs)...
Zearalenone (ZEN) is a kind of nonsteroidal mycotoxin that considered risk affecting the safety human food and livestock feed causes oxidative damages in mammalian cells. Selenomethionine (SeMet) was indicated to have antioxidant activity received great interest investigating role SeMet as therapeutic agent oxidation. Therefore, aim this study investigate hormetic DL-SeMet porcine intestinal epithelial J2 (IPEC-J2) cells against ZEN-induced stress injury. As result experiment, 30 μg/mL ZEN...
Hypoxia-ischaemia (HI) can induce the death of cerebrovascular constituent cells through oxidative stress. Hydrogen is a powerful antioxidant which activate system. A hypoxia-ischaemia brain damage (HIBD) model was established in 7-day-old SD rats. Rats were treated with different doses hydrogen-rich water (HRW), and pericyte stress damage, function tissue assessed. Meanwhile, vitro-cultured pericytes subjected to oxygen-glucose deprivation concentrations HRW. Oxidative injury measured...
The objective of this study was to evaluate the differences between normal and pale, soft, exudative (PSE)-like chicken breast meat in chemical composition, pH, color, water binding capacity, textural properties, salt-soluble protein (SSP) extraction as well dynamic rheological properties. Compared with meat, PSE-like showed similar moisture, fat, ash content (P > 0.05), but significantly lower < 0.05). It had a higher L* pH SSP Heated batter water-binding characteristics 0.05) reduced gel...
This study was conducted to investigate the effects of dietary supplementation Achyranthes japonica Nakai (AJN) extract as a natural feed additive on growth performance, nutrient utilization, cecal microbiota, excreta noxious gas emission, and meat quality in broilers fed corn-wheat-soybean meal diet. In total, seven hundred twenty 1-day-old male Ross 308 with an average body weight (BW) 43.36 ± 1.42 g were used 35-d feeding trial. Broilers randomly assigned 1 4 treatments. Each treatment...
The purpose of this study was to investigate the effects dietary supplementation non-starch polysaccharide multi-enzyme (NME) in early laying phase hens on production performance, egg quality, nutrient digestibility, and excreta noxious gas emission. In total, 432 Hy-line brown at 18 wk age were used a 10-wk feeding trail. Hens randomly assigned 1 3 treatments with 24 replication 6 per (1 hen cage). Dietary corn-soybean meal-DDGS-based diets supplemented 0 (based diet, CON), 0.05% (NME1),...
Abstract Aim Rheumatoid arthritis (RA) is a prevalent autoimmune disease characterized by immune dysegulation, including an imbalance due to abnormal activation of non‐classical Th1 cells (CD161 + Th1). This study investigated the effects CCR5 on and proliferation CD161 their pathogenicity in patients with RA. Methods The was conducted 53 RA 32 age‐ sex‐matched healthy controls (HC). cell phenotype assessed flow cytometry cytokine levels supernatant were detected ELISA. Results We...
This study aimed to evaluate the effect of dietary supplementation a mixed yeast culture (MYC; Saccharomyces cerevisiae YJM1592 and Kluyveromyces maxianus TB7258 in 1:1 ratio) on growth performance, nutrient digestibility, meat quality, blood parameters, gut health broiler chickens. In total, 576 one-day-old male broilers (Ross 308) with an average initial bodyweight (BW) 37±0.51 g were used 35-day experiment completely randomized design. The randomly assigned 3 treatments: CON, basal diet;...
This study was conducted to evaluate the effects of dietary supplementation Weissella cibaria JW15 (WJW15) isolated from traditional Korean fermented vegetable product (kimchi) as a probiotic feed additive on nutrient digestibility, blood profiles, feces noxious gas emission, and Escherichia coli Lactobacillus counts in adult Beagle dogs. In total, 15 dogs with an average initial body weight 10.20 ± 0.38 kg were randomly assigned into three treatments 14-day feeding trial. Dietary consisted...
As a food contaminant, oxidized oil or lipid oxidative products have been proven to exert toxicological effects on the growth and development of animals humans. Research shows that maternal stress damage might transmit another generation by epigenetic modulation. However, current evidence is still not clear mechanism dietary during pregnancy two generations. This study employed rat model fed with soybean (OSO) lactation explore degree (0, 200, 400, 800 mequiv O2/kg) placental RNA methylation...
In this study, the effects of low-temperature long-time (LTLT) processing on quality Patinopecten yessoensis adductor muscle (PYAM) were investigated at 55°C. The texture processed PYAM was characterized by textural profile analysis (TPA), and significant increases cook loss, hardness, shear force with time during LTLT observed. degradation structural proteins analyzed sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), fragments molecular weights 208 kDa (myosin heavy...
Abstract Background Progressive oxidative stress easily occurs as a result of gradual increase in the intensity maternal metabolism due to rapid foetal development and increased lactation. However, studies on effects processive nutrient transport placenta have received little attention. The present study was conducted sows at 85 days gestation pterostilbene (PTE) status placental transport. Results PTE antioxidant capacity immunoglobulin content mothers’ blood milk, reduced level...