A5100326392- Autism Spectrum Disorder Research
- Attention Deficit Hyperactivity Disorder
- Myofascial pain diagnosis and treatment
- Acupuncture Treatment Research Studies
- Cerebral Palsy and Movement Disorders
- Plant Pathogens and Fungal Diseases
- Traditional Chinese Medicine Studies
- Genetics and Neurodevelopmental Disorders
- Child Development and Digital Technology
- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Cancer-related molecular mechanisms research
- Neurological Disease Mechanisms and Treatments
- Hemoglobin structure and function
- Nerve injury and regeneration
- Plant-Microbe Interactions and Immunity
- Pain Management and Placebo Effect
- Pain Mechanisms and Treatments
- Protein Interaction Studies and Fluorescence Analysis
- Barrier Structure and Function Studies
- GABA and Rice Research
- Cancer, Hypoxia, and Metabolism
- Erythrocyte Function and Pathophysiology
- Medicinal Plant Extracts Effects
- Microtubule and mitosis dynamics
Hunan University of Traditional Chinese Medicine
2018-2025
Tianjin Medical University General Hospital
2025
Wuhan Third Hospital
2025
Tongren Hospital
2025
University of Chinese Academy of Sciences
2024-2025
Zhejiang Provincial Hospital of TCM
2024
Acupuncture And Massage College
2024
Weatherford College
2022
Guangzhou Medical University
2016-2021
Second Affiliated Hospital of Guangzhou Medical University
2016-2021
Astrocytes, the most numerous cells in human brain, play a central role metabolic homeostasis following hypoxic injury. Caveolin-1 (Cav-1), transmembrane scaffolding protein, has been shown to converge prosurvival signaling nerve system. The present study aimed investigate of Cav-1 hypoxia-induced astrocyte We also examined how alleviates apoptotic death. To this end, primary astrocytes were exposed oxygen-glucose deprivation (OGD) for 6 h and subsequent 24-h reoxygenation mimic OGD...
The study investigates the effectiveness of immersive virtual reality (VR) as a nonpharmaceutical approach to manage postoperative pain in patients following thoracoscopic surgery. In this single-center, triple-arm pilot randomized controlled trial (RCT), 61 postsurgical with numerical rating scale (NRS) score ≥4 after receiving standard analgesia were included and assigned either quantum clinics-VR (QTC-VR) group, Placebo-VR or control group. QTC-VR group engaged daily 10-minute interactive...
Background: Low back pain (LBP) is one of the most common symptoms prompting patients to seek treatment. Manual therapy widely used treat LBP. Nevertheless, there a scarcity bibliometric analyses examining worldwide utilization manual for treatment Methods: This research Online Bibliometric overview Platform website (https://bibliometric.com), CiteSpace (6.2.R4), and VOSviewer (1.6.19) provide comprehensive analysis current status prospective developments in field. The Web Science Core...
To evaluate the clinical efficacy of combining interference electrotherapy with rotary traction manipulation in treating cervical spondylotic radiculopathy (CSR), and to assess its impact on function prognosis. A retrospective analysis was conducted data from 214 CSR patients who were treated at Yueyang Central Hospital, Hunan University Chinese Medicine, April 2021 October 2023. The observation group (n=110) received combined therapy using manipulation, while control (n=104) alone. Before...
Background Myocardial Infarction (MI) is a prevalent condition of heart disease. Despite remarkable growth in the treatment diseases, MI remains foremost cause mortality worldwide and significant pathological concern. Objectives The primary aim this work to analyze therapeutic activities flavokawain A on Isoproterenol (ISO)-induced rats. Materials Methods rats were administered with ISO (85 mg/kg) order induce pretreated A. body weights all measured. An analysis was conducted levels uric...
Abstract BACKGROUND Synthetic fungicides raise environmental and health concerns, microorganisms are emerging as promising natural antagonists in plant protection. This study evaluated strain XY101 its volatile organic compounds (VOCs) biocontrol agents against pear Valsa canker caused by Vasal pyri , aiming to identify the antifungal mechanisms key compounds. RESULTS The fungus was identified Trichoderma asperellum . strongly suppressed mycelial growth of on culture plates. A colonization...
We have used vibrational spectroscopy to study bonding in monosubstituted dianionic phosphates, both learn more about basic properties intrinsic this important class of biological substrates and assess the ability provide a "sensor" or probe local environment experienced by phosphoryl group. examined group via for series compounds which substituent was varied systematically extensively. A broad linear correlation bridging P−O(R) bond length pKa alcohol observed. The results indicate that...
Abstract The His-x-Asp (HxD) motif is one of the most conserved structural components catalytic core protein kinases; however, functional role histidine unclear. Here we report that replacement HxD-histidine with Arginine or Phenylalanine in Aurora A abolishes both activity and auto-phosphorylation, whereas Histidine-to-tyrosine impairs without affecting its auto-phosphorylation. Comparisons crystal structures wild-type (WT) mutant demonstrate impairment kinase accounted for by (1)...
Abstract Fusarium wilt, caused by the fungus oxysporum Schlecht. f. sp. vasinfectum (Fov) is a destructive soil-borne cotton disease. To profile genes and pathways responding to Fov infection, we compared transcriptomic responses before after F. inoculation in highly resistant cultivar, Yumian21, susceptible Jimian11. Although overall gene expression pattern was downregulated both cultivars, global cultivar stronger than that cultivar. In addition, expressed of two cultivars mostly differed...
Pear Valsa canker, caused by
Objective: To observe the effect of pressing intervention on skeletal muscle repair myofascial trigger points (MTrPs) in rats and explore mechanism deactivation points. Methods: Thirty SPF were randomly divided into blank group, model group press with 10 each group. The MTrPs models established by blunt striking plus eccentric exercise, then evaluated. was given a self-made device for 14 days, other two groups fed normally. Soft tissue tension (STT) D 0.2 pressure pain threshold (PPT)...
Abstract Background Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by repetitive stereotypical behavior and communication deficits. Currently, it lacks specific clinical treatment method. Pediatric Tuina recent therapy in traditional Chinese medicine (TCM) has been used to treat children with ASD. Nonetheless, remains uncommon given the lack of large-scale evidence-based medical studies. This study aims compare efficacy conventional Methods Eligible will be...
Quality of life (QOL) for patients with chronic gastritis (CG) is interest worldwide and disease-specific instruments are needed clinical research practice. This paper focused on the development validation CG scale under system Life Instruments Chronic Diseases (QLICD-CG) by modular approach both classical test theory generalizability theory.The QLICD-CG was developed based programmed decision procedures including multiple nominal focus group discussions, in-depth interviews quantitative...
Abstract Background: Autism spectrum disorder (ASD) is a neurodevelopmental characterized by impairments in social communication, interaction, and restrictive or repetitive behaviors. Traditional Chinese medicine (TCM) has been used the clinical management of ASD, especially mainland China, where studies have shown promising efficacy. However, this remains to be further explored clarified. Therefore, purpose study was evaluate effectiveness safety conventional treatment-based TCM...
(1)Background: This study employs bibliometric methods to comprehensively understand the fundamental structure of research about Autism Spectrum Disorder (ASD) Signaling Pathways by examining key indicators such as nations, institutions, journals, authors, and keywords.(2) Methodology: We utilized WoScc database retrieve literature relevant ASD Pathways. Through visual analysis tools like CiteSpace VosViewer, we explored keywords, thereby constructing networks.(3) Results: The encompasses...
Background This study employs bibliometric methods to comprehensively understand the fundamental structure of research about Autism Spectrum Disorder (ASD) Signaling Pathways by examining key indicators such as nations, institutions, journals, authors, and keywords. Methodology We utilized WoScc database retrieve literature relevant ASD published between 2013 2023. Through visual analysis tools like CiteSpace VosViewer, we explored keywords, thereby constructing networks. Results 26 The...
Children are highly susceptible to influenza and at high risk for severe cases. Chinese patent medicine (CPM) offers advantages in treating pediatric influenza, but the issue of its improper use is increasingly prevalent clinical practice. To address this, we adopted a dual leadership approach involving methodological experts, guided by evidence-based practice principles. We referred existing guidelines, consensus statements, treatment protocols, designed relevant questions based on “3...