A5050900062- Genomic variations and chromosomal abnormalities
- Cardiovascular Health and Disease Prevention
- Dermatology and Skin Diseases
- Cytokine Signaling Pathways and Interactions
- Psoriasis: Treatment and Pathogenesis
- Cardiovascular Health and Risk Factors
- Gastrointestinal motility and disorders
- Autoimmune Bullous Skin Diseases
- Blood groups and transfusion
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Immunodeficiency and Autoimmune Disorders
- Spondyloarthritis Studies and Treatments
- Asthma and respiratory diseases
- Mast cells and histamine
- Blood disorders and treatments
- HER2/EGFR in Cancer Research
- Infant Health and Development
- Rheumatoid Arthritis Research and Therapies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hemoglobinopathies and Related Disorders
- Heme Oxygenase-1 and Carbon Monoxide
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Genetic Associations and Epidemiology
- Music Therapy and Health
Hong Kong Polytechnic University
2024
Harbin Medical University
2007-2021
Second Affiliated Hospital of Harbin Medical University
2007-2021
Chinese People's Liberation Army
2021
Background It has been shown that a deletion in the late cornified envelope (LCE) gene cluster (LCE3C_LCE3B‐del) is associated with susceptibility to psoriasis European populations. However, relationship remains unclear northern Chinese population. Objectives The aim of present study was clarify this association Methods In total, 970 patients and 1064 healthy controls were recruited polymerase chain reaction assay used determine frequency deletion. effect on assessed using SPSS software...
People with spinal cord injuries often experience constipation. Common surgical and conservative treatments for constipation may have long-term adverse events that outweigh their benefits in relieving symptoms temporarily. This proposed study aims to investigate the effects of acupressure on constipation, quality life, psychosocial well-being, bowel habits a community-based injury population. two-parallel-group, open-label controlled trial will randomly assign 78 eligible participants...
Structural variations (SVs; defined as DNA variants ≥ 50 base pairs) have been associated with various complex human diseases. However, research to screen the whole genome for SVs predisposing psoriasis is lacking.To investigate association of and psoriasis.Using imputation, we performed a genome-wide on five independent cohorts 45 386 participants from Han Chinese population. Fine-mapping analysis, genetic interaction analysis RNA expression were conducted explore mechanism SVs.In total,...
Abstract Psoriasis is an autoimmune inflammatory skin disease with genetic components. Chromosome 4q27 related to many diseases, however, the relationship between psoriasis and has not been fully established yet. The objective of this study investigate association chromosome in Northeastern Chinese Han population. Four common single nucleotide polymorphisms (rs2069762, rs4833837, rs6840978, rs7684187) from were genotyped 400 cases 398 controls population using Multiplex SNaPSHOT method....
The authors have disclosed no conflicts of interest.
Background: Iguratimod (IGU) has demonstrated efficacy and safety for active rheumatoid arthritis (RA) patients in double-blind clinical trials China Japan as a new disease-modifying anti-rheumatic drug (DMARD). There are no studies evaluating the radiographic progression of structural joint damage IGU treatment RA using mTSS primary endpoint. Objectives: Our study was to evaluate monotherapy combined methotrexate (MTX) compared with MTX monotherapy, including inhibitory effects destruction....
Background: WHO survey showed that the prevalence of anxiety and depression in Chinese population patients with chronic diseases were between 3.1% - 4.2% 7.3%, respectively. SLEDAI-2K Hospital Anxiety Depression Scale (HADS) are commonly used to evaluate SLE patients’ disease activity mental health. All Assessments mainly performed by health professionals (HCPs) paper questionnaire previously. SSDM is a novel smart management tool allows do self-assessments on HADS mobile App. Objectives: To...