A5101811953- Rheumatoid Arthritis Research and Therapies
- Sepsis Diagnosis and Treatment
- Dementia and Cognitive Impairment Research
- Lung Cancer Diagnosis and Treatment
- Clinical Reasoning and Diagnostic Skills
- Spine and Intervertebral Disc Pathology
- Lung Cancer Treatments and Mutations
- Pelvic and Acetabular Injuries
- Esophageal Cancer Research and Treatment
- Amyotrophic Lateral Sclerosis Research
- Adrenal Hormones and Disorders
- Alzheimer's disease research and treatments
- Spondyloarthritis Studies and Treatments
- Vitamin C and Antioxidants Research
- Gastric Cancer Management and Outcomes
- Medical Imaging Techniques and Applications
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Spinal Fractures and Fixation Techniques
- HER2/EGFR in Cancer Research
- Advanced Radiotherapy Techniques
- Neurological diseases and metabolism
- Neurological Disorders and Treatments
- Aging and Gerontology Research
- ECG Monitoring and Analysis
Shanghai Sixth People's Hospital
2025
Shanghai Jiao Tong University
2025
Chengdu University of Traditional Chinese Medicine
2025
Shanghai University of Traditional Chinese Medicine
2021-2024
Seventh People's Hospital of Shanghai
2018-2024
Northern Jiangsu People's Hospital
2015-2024
Yangzhou University
2017-2024
Shanghai Chest Hospital
2021
People's Hospital of Kaizhou District
2018
Center for Rheumatology
2017
The combination therapy of hydrocortisone, vitamin C, and thiamine has been proposed as a potential treatment in patients with sepsis septic shock. However, subsequent trials have reported conflicting results relation to survival outcomes. Hence, we performed this randomized controlled trial (RCT) evaluate the efficacy safety early among adult shock.This single-center, double-blind RCT enrolled diagnosis shock within 12 h from Northern Jiangsu People's Hospital between February 2019 June...
Brain glucose hypometabolism is an invariant feature and has significant diagnostic value for Alzheimer's disease. Thiamine diphosphate (TDP) a critical coenzyme metabolism significantly reduced in brain blood samples of patients with disease (AD).To explore the measurement thiamine metabolites AD.Blood TDP, monophosphate, levels were detected using high performance liquid chromatography (HPLC). The study included exploration validation phases. In phase, 338 control subjects 43 AD utilized...
Objective The aim of this study was to validate the reliability Chinese version Addenbrooke's Cognitive Examination III (ACE‐III) for detecting dementia. Furthermore, present compares diagnostic accuracy ACE‐III with that mini‐mental state examination (MMSE). Methods One hundred seventy‐seven patients dementia and 180 healthy controls were included in study. Results very good ( α ‐coefficient = 0.888). There a significant negative correlation between Clinical Dementia Rating Scale score...
Objective To evaluate clinical and radiological outcomes of proximal femoral nail anti‐rotation (PFNA‐II) devices demonstrate the effectiveness PFNA‐II for treatment basicervical fractures in elderly patients. Methods A retrospective review all patients treated with a fracture between January 2013 February 2017 at three different institutions (Shanghai General Hospital, Shanghai Punan Hospital Seventh People's Hospital) was conducted. The X‐ray films were strictly reviewed by trauma surgeons...
The aim of this study was to determine the proportion hidden blood loss (HBL) in patients treated with minimally invasive surgery, and compare HBL between percutaneous pedicle screw fixation (PPSF) mini-open Wiltse approach (MWPSF).From January 2017 2019, a total 119 thoracolumbar fractures were included analysis, which 58 cases received PPSF 61 MWPSF. clinical information demographic results collected compared. And is calculated by combination formulas Nadler, Gross Sehat.Compared group,...
Alzheimer disease (AD) is the most frequent cause of dementia. AD diagnosis, progression, and treatment have not been analyzed nationwide in China. The primary aim this study was to analyze demographic clinical characteristics related cognitive decline patients treated at outpatient clinics We performed a retrospective 1993 10 centers across 8 cities China from March 2011 October 2014. Of these, 891 were followed for more than 1 year. mean age diagnosis 72.0 ± 10.0 years (range 38–96 years),...
Sepsis-3 definitions have been published recently; however, their diagnostic value remains controversial. This study was to assess the accuracy of compared Sepsis-1 by stratifying mortality among adult critically ill patients with suspected infection.A multicenter, prospective cohort conducted from November 10, 2017 October 2018, in five Intensive Care Units (ICUs) at four teaching hospitals. Thirty-day across categories for both and definitions, which were evaluated logistic regression...
To identify potential mutation of the colony stimulating factor 1 receptor gene (CSF1R) in a large Chinese family affected with hereditary diffuse leukoencephalopathy spheroids (HDLS) and analyze genotype-phenotype correlation.The proband was evaluated physically radiologically to ascertain HDLS phenotype. Genomic DNA extracted from peripheral blood samples members. The coding region CSF1R amplified PCR subjected direct sequencing.There were 9 members (5 alive) this five-generation (1 member...
Abstract Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by swelling, pain, and synovial damage. Effective methods lack in the treatment of RA. A traditional prescription use for thousands years China, Huangqi Guizhi Wuwutang granule (HGWG) still chosen to relieve pain prevent joint malformation RA patients. However, no evidence-based medical research has been organized assess effectiveness safety HGWG Methods/design: We will conduct multicenter,...
Abstract Background: Rheumatoid arthritis (RA) is a chronic systemic and autoimmune inflammatory disease ending with the destruction of joints. Current therapies can relieve RA symptoms, but some also bring severe adverse events. Therefore, an effective safe therapeutic strategy remains to be created benefit patients by large. Jia Wei Niu Bang Zi granule (NBZG) consisting RA-fighting Chinese herbals has been used in Longhua Hospital last several decades. NBZG potential effect on RA, which...
The development of intensive care medicine is inseparable from the diversified monitoring data. Intensive has been closely integrated with data since its birth. Critical research requires an integrative approach that embraces complexity critical illness and computational technology algorithms can make it possible. Considering need standardization application big in care, Care Medicine Branch China Health Information Big Data Society, Standard Committee convened expert group, secretary group...
Connecting the digital and real worlds, Industrial Metaverse will enable continuous interaction of information, data decision-making, Empowering industries to digitally solve extremely complex real-world problems create huge social benefits. This paper describes main technologies industrial meta-universe; through case E* meta-universe project, it disassembles analyses technical route in combination with existing technologies, puts forward corresponding improvement suggestions makes its own thinking.
In comparison to Alzheimer's disease (AD), the rate of functional decline is greater in behavioral variant frontotemporal dementia (bvFTD). Nevertheless, unlike AD, there are no US Food and Drug Administration approved therapies for bvFTD. We conducted trial investigate efficacy safety memantine treatment patients with Between Jan 1, 2007 Sep 2013, seventy-six were recruited treated (initiated at 5 mg/day up-titrated mg weekly a maintenance dosage 10 twice daily) this single-arm, open-label,...
The prognosis for 201 patients with carcinoma of the oropharynx, treated mainly by irradiation, was analyzed. crude 5, 10, 15 and 20 year survival rates were 50.3 per cent, 36 26 17 cent respectively, corresponding cure 44, 35, respectively. Patients under 50 years age had a better 5 than those over 60 years. poorly differentiated anaplastic carcinomas well lesions. Early stages much advanced Split course continuous irradiation gave similar results. optimum dose range to 70 Gy. disappearance...