A5075303070- COVID-19 Clinical Research Studies
- Diabetes and associated disorders
- Probiotics and Fermented Foods
- SARS-CoV-2 and COVID-19 Research
- Pancreatic function and diabetes
- Intracranial Aneurysms: Treatment and Complications
- Animal Diversity and Health Studies
- Diabetes Management and Research
- Immune Cell Function and Interaction
- Long-Term Effects of COVID-19
- Hepatitis C virus research
- Essential Oils and Antimicrobial Activity
- Vascular Malformations Diagnosis and Treatment
- Telemedicine and Telehealth Implementation
- Vitamin D Research Studies
- Kawasaki Disease and Coronary Complications
- Moringa oleifera research and applications
- Gestational Diabetes Research and Management
- COVID-19 Impact on Reproduction
- Inflammasome and immune disorders
- Bioactive Compounds and Antitumor Agents
- Vascular Malformations and Hemangiomas
- Gut microbiota and health
- Leaf Properties and Growth Measurement
- Nephrotoxicity and Medicinal Plants
University of Miami
2024-2025
University of Milan
2020-2023
Agricultural Research Center
2012-2023
Kastamonu University
2022
Ain Shams University Hospital
2021
Heliopolis University
2021
Ain Shams University
2021
Foundation Jewish Contemporary Documentation Center
2020
University of Khartoum
2019
Agricultural Genetic Engineering Research Institute
2017
A substantial proportion of patients who have recovered from coronavirus disease-2019 (COVID-19) experience COVID-19-related symptoms even months after hospital discharge. We extensively immunologically characterized COVID-19. In these patients, T cells were exhausted, with increased PD-1+ cells, as compared healthy controls. Plasma levels IL-1β, IL-1RA, and IL-8, among others, also in This altered immunophenotype was mirrored by a reduced ex vivo cell response to both nonspecific specific...
Abstract Background Weight loss in patients with metabolic syndrome has positive effects on cardiovascular and type 2 diabetes risks, but its peripheral cytokines lipid profiles are still unclear. Aim To determine the of diet-induced weight parameters, lipids cytokine profiles. Methods Eighteen adult males (defined according to IDF 2009) Body Mass Index (BMI) between 25 35 kg/m were subjected a balanced hypocaloric diet for 6 months reach at least 5% body loss. Results After loss,...
Recent studies have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may induce metabolic distress, leading to hyperglycemia in patients affected by disease 19 (COVID-19). We investigated the potential indirect and direct effects of SARS-CoV-2 on human pancreatic islets 10 who became hyperglycemic after COVID-19. Although there was no evidence peripheral anti-islet autoimmunity, serum these displayed toxicity islets, which could be abrogated use...
Patients with type 1 diabetes (T1D) may develop severe outcomes during coronavirus disease 2019 (COVID-19), but their ability to generate an immune response against the SARS-CoV-2 mRNA vaccines remains be established. We evaluated safety, immunogenicity, and glycometabolic effects of acute respiratory syndrome 2 (SARS-CoV-2) in patients T1D. A total 375 (326 T1D 49 subjects without diabetes) who received two doses (mRNA-1273, BNT162b2) between March April 2021 at ASST Fatebenefratelli Sacco...
Background: Arteriovenous malformations (AVMs) are complex vascular anomalies with a high risk of hemorrhage and neurological deficits, especially when located in eloquent brain regions. The eloquence an AVM location is critical factor the treatment planning, influencing both complications long-term functional outcomes. This study aims to compare outcomes between non-eloquent AVMs. Methods: multicenter, retrospective utilized data from Multicenter International Study for Treatment Brain AVMs...
Introduction: The impact of multiple feeding arteries on clinical outcomes cerebral arteriovenous malformations (AVMs) is not well understood. This study aims to compare between AVMs with versus single arteries. Patients and Methods: Data from the Multicenter International Study for Treatment Brain (MISTA) consortium were analyzed. Propensity score matching (PSM) was used balance cohorts. Subgroup analysis conducted ruptured unruptured different treatment options, multivariable logistic...
Measurements of antibodies in bodily fluids (e.g., by ELISA) have provided robust and reproducible results for decades such assays been validated monitoring B-cell immunity. In contrast, measuring T-cell immunity has proven to be a challenge due the need test live cells functional ex vivo. Several previous efforts looking into reproducibility vivo between different laboratories, or even within same laboratory, rather discouraging results. The hypothesis we tested this study is that those...
To assess the effect of a fermented rice-flour obtained from Lactobacillus paracasei CBA L74 in managing infants with moderate to severe atopic dermatitis. Infants dermatitis, aged 6-36 months, were randomly assigned receive once-daily consumption rice flour containing heat-killed probiotic or placebo for 12 weeks as supplementary approach topical treatment. Primary outcome was SCORAD index change baseline weeks; secondary outcomes gut microbiota composition, evaluated by analysis fecal...
1,3,4-Thiadiazole molecules (1-4) were synthesized by the reaction of phenylthiosemicarbazide and methoxy cinnamic acid in presence phosphorus oxychloride, characterized with UV, FT-IR, 13C-NMR, 1H-NMR methods. DFT calculations (b3lyp/6-311++G(d,p)) performed to investigate structures' geometry physiochemical properties. Their antibacterial activity was screened for various bacteria strains such as Enterobacter aerogenes, Escherichia coli ATCC 13048, Salmonella kentucky, Pseudomonas...
Introduction Gestational diabetes mellitus (GDM) is the most frequent metabolic complication during pregnancy and associated with development of short-term long-term complications for newborns, large-for-gestational-age (LGA) being particularly common. Interestingly, mechanism behind altered fetal growth in GDM only partially understood. Research design methods A proteomic approach was used to analyze placental samples obtained from healthy pregnant women (n=5), patients (n=12) LGA (n=5)....
The aim of this study was to find an association between serum concentration vitamin D and receptor (VDR) polymorphisms achieve a sustained virological response (SVR).We conducted case-control in which 250 participants were recruited divided into three groups (100 chronic hepatitis C [CHC] patients who achieved SVR, 100 CHC did not SVR 50 apparently healthy individuals as controls). Blood samples collected measure concentration, four VDR (FokI, ApaI, TaqI, BsmI) detected using polymerase...
Coronavirus disease 19 (COVID-19) is clinically less severe in children, even if the wide variety and degree of severity symptoms reported children pose a still-unresolved challenge for clinicians. We performed an in-depth analysis immunological profiles 18 hospitalized SARS-CoV-2-infected whose results were compared to those obtained from 13 age- sex-matched healthy controls (HC). The patients categorized as paucisymptomatic/moderate (55.6%) or severe/critical (44.5%) according established...
Soft cheese made from buffaloes milk mixed with camel at different concentrations (90, 80, 70, 60 %) and (10, 20, 30, 40 respectively, the soft (control their treatments) were stored for days 40C. The chemical composition, microbiological organoleptic properties determined all samples during storage periods (fresh, 45 days). compositions results showed that values of total solids, fat, protein ash increased increasing amount milk, while salt was decreased periods. revealed raw contained 13X...
The aim of this study was carried to evaluate the role natural antioxidant and antimicrobial activity against Listeria monocytogenes Pseudomonas putida from each thyme sage powders as well their ethanolic extracts in beef burger help factories extend shelf-life products under storage at -18 C. Results revealed that by using 1.5 % powder 0.1% extract represented optimum concentration for decreasing count but gave highest decreases population especially after 60 days freezing condition.On...
In this study 30 samples each packet and unpacked white cheese (high, middle low salt cheese) were collected from different retail markets in Cairo.All examined evaluated chemically microbiologically.The results revealed that, highest contents of protein, carbohydrate, Ca P 12.70, 7.00, 1.72 1.85% high packed cheese, respectively.Lowest fat, fiber, ash, moisture ,NaCl.and pH value represented 21.70, 8.00, 1.29, 41.39, 0.85% 3.52 , respectively.The total bacterial counts was similar all as...
n experiment was conducted to investigate effects of supplemented L-carnitine, ascorbic acid and probiotics on productive performance, carcass characteristics some bacterial histological aspects in locally-developed broiler strain.252 unsexed chicks 2 weeks age were reared up 8 distributed into 7 treatments 6 replicates birds each.The experimental groups as follows: T1: Control group fed basal diet.T2: Basal diet with 500 mg / Kg diet.T3: 1000 diet.T4: 75 L-carnitine diet.T5: 150 diet.T6:...