Damian Kawecki
A5028225604- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrhythmias and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Obstructive Sleep Apnea Research
- Cardiovascular Effects of Exercise
- Peripheral Artery Disease Management
- Cardiac Structural Anomalies and Repair
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Valve Diseases and Treatments
- Antimicrobial Resistance in Staphylococcus
- Blood Pressure and Hypertension Studies
- Cerebrovascular and Carotid Artery Diseases
- Mechanical Circulatory Support Devices
- Coronary Artery Anomalies
- Cardiomyopathy and Myosin Studies
- Cardiovascular Health and Disease Prevention
Medical University of Silesia
2016-2025
University Hospital of Basel
2022
University of Basel
2017-2022
Freiwillige Akademische Gesellschaft
2022
University of Silesia in Katowice
2021
Masaryk University
2019
University Hospital Brno
2019
Silesian Center for Heart Disease
2018
Tuen Mun Hospital
2016
Górnośląskie Centrum Medyczne
2012
Background: Four strategies for very early rule-out of acute myocardial infarction using high-sensitivity cardiac troponin I (hs-cTnI) have been identified. It remains unclear which strategy is most attractive clinical application. Methods: We prospectively enrolled unselected patients presenting to the emergency department with symptoms suggestive infarction. The final diagnosis was adjudicated by 2 independent cardiologists. Hs-cTnI levels were measured at presentation and after 1 hour in...
Abstract BACKGROUND Clinical performance of the novel high-sensitivity cardiac troponin I (Siemens-hs-cTnI-Centaur) assay is unknown. We aimed to clinically validate Siemens-hs-cTnI-Centaur and develop 0/1-h 0/2-h algorithms. METHODS enrolled patients presenting emergency department with symptoms suggestive acute myocardial infarction (AMI). Final diagnoses were centrally adjudicated by 2 independent cardiologists including all clinical information twice: first, using serial hs-cTnT...
Until now, high-sensitivity cardiac troponin (hs-cTn) assays were mainly developed for large central laboratory platforms. This study aimed to assess the clinical performance of a point-of-care (POC)-hs-cTnI assay in patients with suspected myocardial infarction (MI). enrolled presenting emergency department symptoms suggestive MI. Two cardiologists centrally adjudicated final diagnosis using all data including imaging. The primary objective was directly compare diagnostic accuracy...
We aimed to evaluate the impact of age on performance European Society Cardiology (ESC) 0/1h-algorithms and derive externally validate alternative cut-offs specific older patients.We prospectively enrolled patients presenting emergency department (ED) with symptoms suggestive acute myocardial infarction in three large diagnostic studies. Final diagnoses were adjudicated by two independent cardiologists. High-sensitivity cardiac troponin (hs-cTn) T I concentrations measured at presentation...
The aim of this study was to validate the clinical performance Beckman Access high-sensitivity cardiac troponin I (hs-cTnI) assay.We enrolled patients presenting emergency department with symptoms suggestive acute myocardial infarction (AMI). Final diagnoses were centrally adjudicated by 2 independent cardiologists all information including imaging twice: first, using serial hs-cTnT (Elecsys, primary analysis), and second, hs-cTnI (Architect, secondary analysis) measurements in addition...
Collaboration for the Diagnosis and Evaluation of Acute Coronary Syndrome (CoDE-ACS) is a validated clinical decision support tool that uses machine learning with or without serial cardiac troponin measurements at flexible time point to calculate probability myocardial infarction (MI). How CoDE-ACS performs different points measurement compares guideline-recommended diagnostic pathways rely on fixed thresholds uncertain.
Background: Combining 2 signals of cardiomyocyte injury, cardiac troponin I (cTnI) and T (cTnT), might overcome some individual pathophysiological analytical limitations thereby increase diagnostic accuracy for acute myocardial infarction with a single blood draw. We aimed to evaluate the performance combinations high-sensitivity (hs) cTnI hs-cTnT early diagnosis infarction. Methods: The combining hs-cTnI (Architect, Abbott) (Elecsys, Roche) concentrations (sum, product, ratio, combination...
Abstract BACKGROUND We aimed to validate the clinical performance of high-sensitivity cardiac troponin I [VITROS® Immunodiagnostic Products hs Troponin (hs-cTnI-VITROS)] assay. METHODS enrolled patients presenting emergency department with symptoms suggestive acute myocardial infarction (AMI). Final diagnoses were centrally adjudicated by 2 independent cardiologists considering all information, including imaging: first, using serial hs-cTnT-Elecsys (primary analysis) and, second,...
Background: The utility of BNP (B-type natriuretic peptide), NT-proBNP (N-terminal proBNP), and hs-cTn (high-sensitivity cardiac troponin) concentrations for diagnosis risk-stratification syncope is incompletely understood. Methods: We evaluated the diagnostic prognostic accuracy BNP, NT-proBNP, hs-cTnT, hs-cTnI concentrations, alone against those clinical assessments, in patients >45-years old presenting with to emergency department a prospective multicenter study. hs-cTnT were measured...
Background: The non–ST-segment–elevation myocardial infarction (NSTEMI) guidelines of the European Society Cardiology (ESC) recommend a 3h cardiac troponin determination in patients triaged to observe-zone ESC 0/1h-algorithm; however, no specific cutoff for further triage is endorsed. Recently, 0/3h high-sensitivity T (hs-cTnT) change (7 ng/L) was proposed, warranting external validation. Methods: Patients presenting with acute chest discomfort emergency department were prospectively...
IMPORTANCEIn contrast to type 1 myocardial infarction (T1MI) caused by atherothrombosis, characteristics and outcomes of 2 (T2MI) supply-demand mismatch are incompletely understood.OBJECTIVE To explore the patients with T2MI compared those T1MI. DESIGN, SETTING, AND PARTICIPANTSIn a prospective, international, multicenter cohort study including 12 emergency departments (EDs) in 5 European countries, unselected presenting acute chest discomfort were enrolled from April 2006 2018.Follow-up was...
Abstract BACKGROUND We aimed to derive and externally validate a 0/2-h algorithm using the high-sensitivity cardiac troponin I (hs-cTnI)-Access assay. METHODS enrolled patients presenting emergency department with symptoms suggestive of acute myocardial infarction (AMI) in 2 prospective diagnostic studies central adjudication. Two independent cardiologists adjudicated final diagnosis, including all available medical information imaging. hs-cTnI-Access concentrations were measured at...
Rapid and accurate noninvasive discrimination of type 2 myocardial infarction (T2MI), which is because a supply-demand mismatch, from 1 (T1MI), arises via plaque rupture, essential, treatment differs substantially. Unfortunately, this major unmet clinical need, even high-sensitivity cardiac troponin (hs-cTn) measurement provides only modest accuracy.
Abstract Background Multimorbidity, as the coexistence of two or more chronic conditions, is a growing health challenge that affects course acute cardiac conditions. The preferred personalized approach to patient requires modification according rising burden multimorbidity. Aim aim study was examine prognosis patients with cardiovascular (CV) and non-cardiovascular (NCV) multimorbidity (MMB) after coronary syndrome (ACS). Methods analysis included from prospective registry suspected ACS...