A5055043921- Sarcoma Diagnosis and Treatment
- Tumors and Oncological Cases
- Bone Tumor Diagnosis and Treatments
- Cancer Diagnosis and Treatment
- Pelvic floor disorders treatments
- Nonmelanoma Skin Cancer Studies
- Facial Nerve Paralysis Treatment and Research
- Head and Neck Cancer Studies
- Advanced Radiotherapy Techniques
- Oral health in cancer treatment
- Urinary Bladder and Prostate Research
- Reconstructive Facial Surgery Techniques
- Face recognition and analysis
- Childhood Cancer Survivors' Quality of Life
- Cleft Lip and Palate Research
- Surgical site infection prevention
- Lung Cancer Treatments and Mutations
- Ear Surgery and Otitis Media
- Ear and Head Tumors
- Craniofacial Disorders and Treatments
- Colorectal and Anal Carcinomas
- Management of metastatic bone disease
- Bone fractures and treatments
- Cancer and Skin Lesions
- Dental Radiography and Imaging
University Medical Center Utrecht
2021-2025
Princess Máxima Center
2021-2025
Amsterdam University Medical Centers
2018-2023
Utrecht University
2022-2023
Amsterdam UMC Location University of Amsterdam
2017-2019
University of Amsterdam
2018-2019
Amsterdam UMC Location Vrije Universiteit Amsterdam
2013-2018
Erasmus MC Cancer Institute
2008
ACTA (United States)
1998
Weatherford College
1998
Three-dimensional (3D) imaging of the face is being used extensively in medicine for clinical decision making, surgical planning, and research. Nowadays, several companies are offering a broad range 3D systems, varying price, method, mobility. However, most planning evaluation methods created validated solely with one system. Therefore, it important to analyze possible differences surface reconstruction between different systems. The objective this study was three systems: 3dMDface system,...
Rhabdomyosarcoma, although rare, is the most frequent soft tissue sarcoma in children and adolescents. It can present as a mass at nearly any site body, with common presentations head neck, genitourinary tract extremities. The optimal diagnostic approach management of rhabdomyosarcoma require multidisciplinary team multimodal treatment, including chemotherapy local therapy. Survival has improved over last decades; however, further improvement essential current 5-year overall survival ranging...
Abstract Objective Survivors of pediatric head and neck rhabdomyosarcoma (HNRMS) are at risk developing endocrinopathies following local treatment, resulting from radiation damage to the pituitary gland, hypothalamus, or thyroid often a young age. Our aim was determine prevalence endocrine dysfunction in long-term HNRMS survivors compare anterior insufficiency (API) among different treatment strategies: external beam with photons, protons, microscopically radical surgery combined...
The authors report the prospective evaluation of reduced dose alkylator chemotherapy combined with radiotherapy for European Pediatric Soft Tissue Sarcoma Study Group (EpSSG) standard risk nonalveolar rhabdomyosarcoma (NA-RMS).
Medication use during pregnancy and lactation can be unavoidable, but knowledge on safety for the fetus or breastfed infant is limited among patients healthcare providers.This study aimed to determine (a) prevalence of medication in pregnant lactating women a tertiary academic center, (b) types these medicines, (c) influence initiation breastfeeding.This used cross-sectional survey ( N = 292) who underwent high-risk low-risk deliveries. Data about their prescribed, over-the-counter,...
ABSTRACT Objective To introduce a simple, well‐standardised vaginal ultrasound technique and to compare the position mobility of bladder neck in continent stress incontinent women using this technique. Design A single‐centre prospective case‐control study. Setting Ikazia Hospital, Rotterdam, The Netherlands. Subjects One hundred sixty women; randomly chosen referred our outpatient department who volunteered for study develop standardised technique, fifty stress‐incontinent controls...
Background: Systematic reviews have identified the need for a patient-reported outcome measure facial nerve paralysis (FNP). The aim of this study was to determine psychometric properties FACE-Q Craniofacial module scales when used in combined sample children and older adults with FNP. Methods: Data were collected between December 2016 2019. We conducted qualitative interviews data from patients aged 8 years Rasch measurement theory analysis examine reliability validity relevant FNP sample....
The CLEFT-Q includes 12 independently functioning scales that measure appearance (face, nose, nostrils, teeth, lips, jaws), health-related quality of life (psychological, social, school, speech distress), and function, an eating/drinking checklist. Previous qualitative research revealed the has content validity in noncleft craniofacial conditions. This study aimed to examine psychometric performance international sample patients with a broad range facial conditions.Data were collected...
Head and neck rhabdomyosarcoma (HNRMS) survivors are at risk to develop adverse events (AEs). The impact of these AEs on psychosocial well-being is unclear. We aimed assess HNRMS examine whether outcomes were associated with burden therapy.Sixty-five (median follow-up: 11.5 years), treated in the Netherlands United Kingdom between 1990 2010 alive ≥2 years after treatment visited outpatient multidisciplinary follow-up clinic once, which scored based a predefined list according Common...
The FACE-Q Craniofacial Module is a patient-reported outcome measure designed for patients aged 8 to 29 years with conditions associated facial difference. In part 1, we describe the psychometric findings original CLEFT-Q scales tested in cleft and noncleft conditions. aim of this study was examine performance new scales.Data were collected between December 2016 2019 from visible or functional Rasch measurement theory (RMT) analysis used properties each scale. Scores transformed 0 (worst)...
Abstract Introduction Radiotherapy is essential for achieving and maintaining local control in head neck rhabdomyosarcoma (HNRMS) patients. However, radiotherapy may cause outgrowth disturbances of facial bone soft tissue, resulting asymmetry. The aim this study was to develop a method visualize measure asymmetry HNRMS survivors using three‐dimensional (3D) imaging techniques. Methods Facial deformity evaluated multidisciplinary clinical assessment 75 survivors, treated with external beam...
Abstract Introduction Adverse events (AE) of treatment are prevalent and diverse in head neck rhabdomyosarcoma (HNRMS) survivors. These AEs often reported by physicians; however, patients' perceptions specific AE not well known. In this study, we explored patient‐reported outcomes measuring appearance, health‐related quality life (HRQOL), facial function HNRMS Second, assess the relationship between physician grading patient reporting. Materials Methods Survivors pediatric HNRMS, diagnosed...
Purpose: Despite widespread concerns of radiotherapy toxicity in children with head and neck tumors, recent Children's Oncology Group (COG) findings suggest that the use 45 Gy results an unacceptably high rate local recurrences patients low-risk orbital rhabdomyosarcoma. We therefore evaluated outcomes our pediatric who received GyRBE using proton therapy. Material methods: To assess disease control toxicity, we reviewed medical records 30 (≤21 years old) COG stage 1, group III embryonal...
To study the position of bladder neck in a group women before and after successful colposuspension to compare them with parous continent controls.A single setting longitudinal descriptive case controls.Ikazia Hospital, Rotterdam, The Netherlands.Twenty-five urodynamically proven genuine stress incontinence who underwent Burch fifty controls volunteered for comparison.The relation symphysis pubis studied vaginal ultrasound.The cranio caudål displacement during straining was 11 mm incontinent...
Abstract Background The four different local therapy strategies used for head and neck rhabdomyosarcoma (HNRMS) include proton (PT), photon (RT), surgery with radiotherapy (Paris‐method), brachytherapy (AMORE). Local control survival is comparable; however, the impact of these treatments on facial deformation still poorly understood. This study aims to quantify investigates differences in between treatment modalities. Methods Across European North American institutions, HNRMS survivors...
Purpose: To assess the accuracy of dose calculations for Cyberknife treatment small lung tumors, performed with Monte Carlo Dose Calculation algorithm (Multiplan v2.1 and later). Method Materials: Verification measurements were in slab phantoms a newly constructed anthropomorphic thorax phantom, both made tissue equivalent materials (Gammex RMI). The modular phantom can be configured spherical Solid Water tumors 10, 20 or 30 mm diameter, embedded material. Measurements mainly Gafchromic EBT...
Purpose: The frequency and patterns of HL in a HNRMS survivor cohort were investigated. A dose–effect relationship between the dose to cochlea was explored. Methods: Dutch survivors treated for 1993 2017 with no relapse at least two years after end treatment eligible inclusion. evaluated pure-tone audiometry. graded according Muenster, Common Terminology Criteria Adverse Events (CTCAE) v4.03 International Society Paediatric Oncology (SIOP) classification. We defined deleterious as Muenster ≥...