A5010059460- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Intracranial Aneurysms: Treatment and Complications
- Surgical site infection prevention
- Cardiac Imaging and Diagnostics
- Intracerebral and Subarachnoid Hemorrhage Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Olfactory and Sensory Function Studies
- Orthopedic Infections and Treatments
- Peripheral Neuropathies and Disorders
- Advanced Chemical Sensor Technologies
- Clinical practice guidelines implementation
- Neurological Complications and Syndromes
- HER2/EGFR in Cancer Research
- Essential Oils and Antimicrobial Activity
- Atrial Fibrillation Management and Outcomes
- Otitis Media and Relapsing Polychondritis
- MRI in cancer diagnosis
- Vasculitis and related conditions
University of Modena and Reggio Emilia
2018-2023
Azienda Unita' Sanitaria Locale Di Modena
2019-2023
Heidelberg University
2020
University Hospital Heidelberg
2020
Diakonissenkrankenhaus
2020
Sapienza University of Rome
2013-2018
Azienda Ospedaliera Sant'Andrea
2018
Policlinico di Modena
2018
Innsbruck Medical University
2014
Università Cattolica del Sacro Cuore
1989-1993
Background and Purpose: Different studies have pointed that CT perfusion (CTP) could overestimate ischemic core in early time window. We aim to evaluate the influence of collateral status on overestimation. Methods: Retrospective single-center study including patients with anterior circulation large-vessel stroke achieved reperfusion after endovascular treatment. Ischemic were automatically estimated baseline CTP using commercially available software. CTP-derived was considered as tissue a...
<h3>Background and Objective</h3> A variety of neurological disorders has been reported as presentations or complications COVID-19 infection. The objective this study was to determine their incidence dynamics long-term functional outcome. <h3>Methods</h3> Neuro-COVID Italy a multicentre, observational, cohort with ambispective recruitment prospective follow-up. Consecutive hospitalized patients presenting new associated infection (neuro-COVID), independently from respiratory severity, were...
Background and Purpose: Observational studies have suggested a link between fibromuscular dysplasia spontaneous cervical artery dissection (sCeAD). However, whether patients with coexistence of the two conditions distinctive clinical characteristics has not been extensively investigated. Methods: In cohort consecutive first-ever sCeAD, enrolled in setting multicenter IPSYS CeAD study (Italian Project on Stroke Young Adults Cervical Artery Dissection) January 2000 June 2019, we compared...
Background and Purpose: We aim to evaluate if good collateral flow (CF) modifies endovascular therapy (EVT) efficacy on large-vessel stroke. To do that, we used final degree of reperfusion number device-passes performed, factors previously associated with better functional outcome, as main outcome measures. Methods: Single-center retrospective study including consecutive stroke patients receiving EVT for anterior circulation CF was assessed CT angiography before using a validated 4-grade...
A rat model of chronic staphylococcal osteomyelitis was developed. Fibrin glue (5 microliters) and Staphylococcus aureus (2 x 10(6) CFU/5 were inoculated into the proximal metaphysis tibia. The rats killed at intervals between 1 6 months, tibias removed. Induced lesions evaluated by radiographic, macroscopic, histological examinations bacterial counts. Roentgenograms revealed in more than 90% tibias. Gross bone pathology skeletal deformation, new formation, abscesses, draining skin fistulas...
Multiple system atrophy is a rare and fatal neurodegenerative disorder characterized by progressive autonomic failure, ataxia parkinsonism in any combination. The clinical manifestations reflect central striatonigral degeneration as well olivopontocerebellar atrophy. Glial cytoplasmic inclusions, composed of α-synuclein other proteins are considered the cellular hallmark lesion. cerebellar variant MSA (MSA-C) denotes distinctive motor subtype adult onset sporadic gait ataxia, scanning...
Alemtuzumab is an anti-CD52 monoclonal antibody indicated for the treatment of relapsing-remitting multiple sclerosis (RRMS) with high disease activity despite previous disease-modifying therapies.1 It administered by IV infusion in a first cycle 12 mg/d 5 days (60 mg) and second 3 (36 after months from cycle. The most common infusion-associated reaction (IAR), occurring 90% alemtuzumab-treated patients, cytokine-release syndrome, which managed premedicating steroids treating symptomatic...
Central nervous system vasculitis (CNSV) is an uncommon and poorly understood form of vasculitis. Early recognition important because medical treatment might improve the outcome. However, randomized clinical trials on CNSV do not exist. Endovascular has been reported in few cases, but no data exist for intracranial stenting. We report 2 cases patients with suspected recurrent episodes, treated A 48-year-old man had relapsing episodes right hemiparesis. Neuroradiological exams showed severe...
Introduction The role of computed tomography perfusion (CTP) in prediction hemorrhagic transformation (HT) has been evolving. We aimed to study the automated post-processing software HT using commercially available RAPID software. Methods Two hundred eighty-two patients with anterior circulation ischemic stroke, who underwent CTP post-processing, were retrospectively enrolled and divided into ( n = 91) non-HT groups 191). RAPID-generated maps reviewed. Mismatch volume ratio, time maximum...
Abstract Background Olfactory and taste disorders were reported in up to 30%–80% of COVID‐19 patients. The purpose our study was objectively assess smell impairment patients correlate olfactory function with viral recovery. Methods Between 15 30 April 2020, hospitalized confirmed SARS‐CoV‐2 infection underwent an objective assessment the Smell Identification subtest Sniffin’ Sticks Test (SI‐SST). Association between recovery SI‐SST performance evaluated. Results 51 enrolled (49% males, mean...
The Garcin syndrome is a rare condition characterized by multiple unilateral cranial nerve palsy, without neither long-tract involvement nor intracranial hypertension. Non-Hodgkin lymphoma systemic malignant disease that localizes in minority of cases the central nervous system. We report case revealed diffuse large B cell (DLBCL) located skull base and right kidney. reached diagnosis mean nonstandard, mini-invasive, transforamen ovale biopsy lesion (Hartel's route). nature renal mass was...
Assessment of patients suspected to have an acute stroke at the prehospital level or non-stroke centers may be challenging. We aimed validate a novel Artificial Intelligence (AI) based application (CVAid) for smartphones able score neurological deficit in patients. Methods: Acute patients, admitted two different units, and healthy volunteers were studied. A certified neurologist determined NIHSS bedside. user recorded short exam, using CVAid application. The software processed video file...