É. Denes

ORCID: 0000-0001-5321-3171
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Research Areas
  • Orthopedic Infections and Treatments
  • Infectious Diseases and Tuberculosis
  • Infective Endocarditis Diagnosis and Management
  • Herpesvirus Infections and Treatments
  • Streptococcal Infections and Treatments
  • Surgical site infection prevention
  • Antimicrobial Resistance in Staphylococcus
  • Infectious Encephalopathies and Encephalitis
  • Bacterial Infections and Vaccines
  • Pneumonia and Respiratory Infections
  • Antibiotic Resistance in Bacteria
  • HIV Research and Treatment
  • Mycobacterium research and diagnosis
  • Hematological disorders and diagnostics
  • Reconstructive Surgery and Microvascular Techniques
  • HIV/AIDS drug development and treatment
  • Cytomegalovirus and herpesvirus research
  • Mosquito-borne diseases and control
  • Orthopaedic implants and arthroplasty
  • Antibiotic Use and Resistance
  • Autoimmune and Inflammatory Disorders
  • Autoimmune Bullous Skin Diseases
  • Hepatitis C virus research
  • Urinary Tract Infections Management
  • Thermal Regulation in Medicine

Centre Hospitalier Universitaire de Limoges
2011-2024

Délégation Paris 6
2024

Centre Hospitalier de la Côte Basque
2023

Hôpital Universitaire Dupuytren
2006-2022

Hôpital Bichat-Claude-Bernard
2022

Université Paris Cité
2022

Centre Européen de la Céramique
2017-2022

Assistance Publique – Hôpitaux de Paris
2022

Inserm
2022

Université Claude Bernard Lyon 1
2022

We assessed the determinants of mortality in infective endocarditis (IE), using national hospital discharge databases (HDD) 2011.IE stays were extracted from HDD, with a definition based on IE-related diagnosis codes. This has been according to Duke criteria by checking sample medical charts IE giving predictive positive value 86.1% (95% confidence interval (CI): 82.7% - 89.5%). The impact heart valve surgery survival studied if performed during initial stay, and over year follow-up. Risk...

10.1371/journal.pone.0223857 article EN cc-by PLoS ONE 2019-10-25

Severe neurological deficit (SND) is a rare but major complication of pyogenic vertebral osteomyelitis (PVO). We aimed to determine the risk factors and variables associated with clinical improvement for SND during PVO. This case–control study included patients without PVO-associated enrolled in prospective randomized antibiotic duration study, managed 8 French referral centers. Risk were determined by logistic regression. Ninety-seven cases, 297 controls included. epidural abscess [adjusted...

10.1097/md.0000000000006387 article EN cc-by-nc Medicine 2017-05-01
Sarah Tubiana Emmanuelle Varon Charlotte Biron M.-C. Ploy Bruno Mourvillier and 95 more Muhamed‐Kheir Taha Matthieu Revest Claire Poyart Guillaume Martin‐Blondel Marc Lecuit Éric Cua Blandine Pasquet Marie Préau Bruno Hoen Xavier Duval Xavier Duval Bruno Hoen Bruno Mourvillier Marie-Cécile Ploy Sarah Tubiana Emmanuelle Varon François Caron Pierre‐Édouard Bollaert Olivier Gaillot Muhamed‐Kheir Taha Claire Poyart Stéphane Bonacorsi François Vandenesch Emmanuelle Cambau Marc Lecuit Alain Gravet Bruno Frachet T. de Broucker D Lévy-Brühl F. Raffi Nadia Anguel Laurent Argaud S. Arista Laurence Armand-Lefevre Stéphanie Balavoine Régine Baraduc Guilène Barnaud Guillaume Béraud Louis Bernard Georges Bernars Dominique Bertei Emilie Bessède Typhaine Billard Pomares Charlotte Biron Stéphane Bland J. Boileau Patrice Boubeau Sandra Bourdon Aurore Bousquet Sophie Boyer A. Bozorg–Grayeli Laurent Bret Cédric Bretonnière François Bricaire Elsa Brocas Michel Brun J. Buret Christophe Burucoa Jean Cabalion Mathieu Cabon Emmanuelle Cambau G. Camuset Christophe Canevet François Caron Anne Carricajo Bernard Castan Éric Caumes Charles Cazanave Amélie Chabrol T. Challan-Belval Vanessa Chanteperdrix-Marillier C. Chaplain Caroline Charlier-Woerther H. Chaussade Catherine Chirouze Bernard Clair Julien Colot Jean‐Marie Conil Hugues Cordel Philippe Cormier Joël Cousson Pierrick Cronier Éric Cua Anne Dao-Dubremetz S. Dargère Nicolas Degand S. Dekeyser D. Delaune É. Denes Pierre‐François Dequin Diane Descamps Élodie Descloux Jean-Luc Desmaretz Jean‐Luc Diehl Jérôme Dimet

10.1016/j.cmi.2019.12.020 article EN publisher-specific-oa Clinical Microbiology and Infection 2020-01-10

Abstract We report the case of human herpesvirus 6 (HHV-6) encephalomyelitis in an immunocompetent patient, which was confirmed by viral amplification from cerebrospinal fluid. Cidofovir used followed ganciclovir because adverse effect to probenecid. The patient recovered. HHV-6 should be recognized as one causes encephalomyelitis.

10.3201/eid1004.030587 article EN cc-by Emerging infectious diseases 2004-04-01

Fluorodesoxyglucose Positron Emission Tomography (PET/CT) has never been compared to Chest-Abdomen-Pelvis CT (CAPCT) in patients with a fever of unknown origin (FUO), inflammation (IUO) and episodic (EFUO) through prospective multicentre study. In this study, we investigated the diagnostic value PET/CT CAPCT these patients. The trial was performed between 1 May 2008 28 February 2013 7 French University Hospital centres. Patients who fulfilled FUO, IUO or EFUO criteria were included....

10.3390/jcm11020386 article EN Journal of Clinical Medicine 2022-01-13

Vascular graft infection (VGI) remains a severe disease with high mortality and relapse rates. We performed retrospective single-center cohort study to highlight factors associated long-term all-cause in patients vascular infection.All hospitalized our facility over 10 years for VGI were included. was defined by the presence of or an aortic stent (stent fabric), 2 criteria among clinical, biological, imaging, microbiological elements favor VGI. The primary outcome mortality. Empirical...

10.1093/ofid/ofac054 article EN cc-by-nc-nd Open Forum Infectious Diseases 2022-02-01

Introduction
 Our aim was to determine the impact of antimicrobial stewardship tools (AST) and COVID-19 pandemic on antibiotic consumption (AC).
 Methods
 We used national software Consores AC in DDD / 1000 days hospitalization from 2017 2022 voluntary private hospitals France. The AST considered were 1/ internal guidelines 2/ list antibiotics with restricted access 3/ presence an referent or 4/ ID specialist 5/ proof annual meeting resistance. Institutions dedicated units...

10.20944/preprints202401.1215.v1 preprint EN 2024-01-16

Our aim was to determine the impact of antimicrobial stewardship tools (ASTs) and COVID-19 pandemic on antibiotic consumption (AC). We used national software Consores® AC in DDD/1000 days hospitalization from 2017 2022 voluntary private hospitals France. The ASTs considered were: 1. internal guidelines; 2. list antibiotics with restricted access; 3. presence an referent or 4. ID specialist; 5. proof annual meeting resistance. Institutions dedicated units for patients were specified. In 30...

10.3390/antibiotics13020180 article EN cc-by Antibiotics 2024-02-12
Jean‐Ralph Zahar Philippe Lesprit Stéphane Ruckly A. Eden Hikombo Hitoto and 95 more Louis Bernard Stephan Harbarth Jean-François Timsit Christian Brun‐Buisson Nejla Aissa Alain Losniewski Sandrine Hénard Christian Rabaud C. Janssen Léonardo Pagani Stéphane Bland J. Gaillat Jean Pierre Bru Pierre Bonnin Gaelle Clavère Virginie Vitrat Laurence Maulin Luc Quarsaet Helene Roger Jean-Baptiste Euzen É. Denes Elodie Couve-Daecon Catherine Lechiche Jean‐Philippe Lavigne V. Mondain Celine Pulcini Véronique Vernet Garnier Dorothée Lambert Maxime Hentzien Yohan N’Guyen Jean Paul Talarmin Pascaline Rameau Françoise Geffroy Arnaud Salmon‐Rousseau Vincent Cattoir Antoine Froissart Saïd Aberrane Laurence Legout F. Roblot Guillaume Béraud Patricia Pavèse Olivier Belmonte Nicolas Traversier Laurent Bellec Marie Lagrange-Xélot Marie-Pierre Moiton Barbara Kuli P. Longuet A. Scanvic Léa Colombain Milagros Ferreyra Maxime Jean A. Eden E. Laurens Matthieu Saada Hugues Aumaître Martine Malet Frederique Roustant Vincent LeMoing Jean-Pierre Helene Jonathan Theodore Caroline Garandeau J. Caillon Benjamin Olivero D. Boutoille Didier Lepelletier L. Grandière-Pérez Aurélie Beaudron Céline Ramanantsoa C. Varache N Varache N. Crochette Hikombo Hitoto Sophie Blanchi Pascale Penn Bernard Louis D. Vanjak Marie‐Christine Escande René-Gilles Patrigeon Stéphanie Honoré Audrey Barrelet Marlène Amara Jean-Marc Galempoix J.C. Reveil Patricia Bucchiotty C. Couzigou Alban Le Monnier Emilie Boidin Stephane Sire Nelly Luizy Caroline Bronstain Stephan Harbarth Carolina Fankhauser Caroline Brossier Elodie von Dach

10.1016/j.ijantimicag.2016.09.032 article EN International Journal of Antimicrobial Agents 2016-11-16

BACKGROUND: PCR in the cerebrospinal fluid (CSF) has become sole method used for diagnosis of herpes simplex encephalitis (HSE). Nevertheless, results may sometimes be false negative, and this situation other techniques useful. METHODS: 3 patients hospitalised meningoencephalitis with fever showed a negative result virus (HSV) their CSF. We then performed detection intrathecal anti-HSV immunoglobulins (IgGs) CSF analysed level relation to those serum, compared albumin. RESULTS: confirmed...

10.4414/smw.2010.13107 article EN cc-by Schweizerische medizinische Wochenschrift 2010-10-07
Marion Le Maréchal Alexandra Mailles Arnaud Seigneurin Pierre Tattevin J.‐P. Stahl and 95 more Olivier Épaulard Sophie Abgrall Laurent Argaud X. Argémi Nathalie Asseray Guillaume Baille Aurélie Baldolli Thomas Baudry Julien Biberon Charlotte Biron Geneviève Blanchet-Fourcade Mathieu Blot Mickaël Bonnan Anne Bonnetain Élisabeth Botelho-Nevers Frédéric Bourdain D. Boutoille Hélène Brasme Cédric Bruel Fabrice Bruneel Rodolphe Buzelé Etienne Canouï Philippe Casenave Bernard Castan Charles Cazanave Céline Cazorla Thibault Challan-Belval P. Chavanet Catherine Chirouze Johan Courjon Daniel Silva T. de Broucker Arnaud De La Blanchardière Étienne de Montmollin Thècle Degroote Marine Delaroche É. Denes Colin Deschanvres Capucine Diard‐Detoeuf Aurélien Dinh Olivier Épaulard Pierre Fillâtre E. Forestier T. Fraisse Marie Froidure Benjamin Gaborit Amandine Gagneux-Brunon Nicolas Gaillard Arnaud Galbois Mathieu Godement François Goehringer Pascale Goubin Simon Gravier Valentin Greigert I. Gueït Thomas Guimard Carole Henry Maxime Hentzien Jean-Étienne Herbrecht Pierre Jaquet Fanny Jomier Lydie Khatchatourian Solen Kernéis Jessica Krause Morgane Le Bras Manuela Le Cam Marion Le Maréchal G. Le Moal Paul Le Turnier R. Lecomte Anne-Sophie Lecompte Romain Lefaucheur Stéphanie Lejeune François-Xavier Lescure Olivier Lesieur P. Lesprit Guillaume Louis Christelle Lucas Rafaël Mahieu Alain Makinson Guillaune Marc A. Maria Nathalie Marin Aurélie Martin Guillaume Martin‐Blondel M. Martinot Alexandre Mas Philippe Mateu Morgan Matt Laurence Maulin F. Méchaï Jean‐Paul Mira Eugénie Mutez Jérémie Orain Anne Pachart

New diagnostic tools have been developed to improve the diagnosis of infectious encephalitis. Using a prospective cohort encephalitis patients, our objective was identify possible clusters patients with similar patterns among unknown cause (EUC) and describe what extent patient's initial presentation may be predictive etiology, particularly herpes simplex virus (HSV) varicella-zoster (VZV).The National Cohort Infectious Encephalitis in France is an ongoing study implemented 2016. Patients...

10.1093/cid/ciaa598 article EN Clinical Infectious Diseases 2020-05-19
Léa Poussier Alexandra Mailles Pierre Tattevin J.‐P. Stahl Pierre Fillâtre and 95 more Sophie Abgrall Laurent Argaud X. Argémi Nathalie Asseray Guillaume Baille Aurélie Baldolli Julien Biberon Charlotte Biron Geneviève Blanchet-Fourcade Mathieu Blot Anne Bonnetain Élisabeth Botelho-Nevers Frédéric Bourdain D. Boutoille Hélène Brasme Cédric Bruel Fabrice Bruneel Rodolphe Buzelé Etienne Canouï Philippe Casenave Bernard Castan Charles Cazanave Céline Cazorla Thibault Challan-Belval P. Chavanet Catherine Chirouze Tomasz Chroboczek Johan Courjon T. de Broucker Arnaud De La Blanchardière Étienne de Montmollin Thècle Degroote Marine Delaroche É. Denes Colin Deschanvres Capucine Diard‐Detoeuf Aurélien Dinh Olivier Épaulard Pierre Fillâtre E. Forestier Thibault Fraisse Marie Froidure Benjamin Gaborit Amandine Gagneux-Brunon Nicolas Gaillard Arnaud Galbois Mathieu Godement François Goehringer Simon Gravier Valentin Greigert I. Gueït Thomas Guimard Carole Henry Maxime Hentzien Jean-Étienne Herbrecht Pierre Jaquet Fanny Jommier Lydie Katchatourian Solene Kerneis Jessica Krause Manuela Le Cam Marion Le Maréchal G. Le Moal Paul Le Turnier R. Lecomte Anne-Sophie Lecompte Romain Lefaucheur Stéphanie Lejeune François-Xavier Lescure Olivier Lesieur P. Lesprit Guillaume Louis Christelle Lucas Rafaël Mahieu Alain Makinson Guillaune Marc A. Maria Nathalie Marin Aurélie Martin Guillaume Martin‐Blondel M. Martinot Alexandre Mas Philippe Mateu Morgan Matt Laurence Maulin F. Méchaï Jean‐Paul Mira Eugénie Mutez Jérémie Orain Anne Schieber-Pachart Nathalie Pansu S. Patrat-Delon Patricia Pavèse Hélène Pelerin Véronique Pelonde-Erimée

10.1016/j.cmi.2024.03.017 article EN Clinical Microbiology and Infection 2024-03-26

We report two cases of endocarditis due to Moraxella osloensis. Only one previous case such infection has been described. These infections occurred in immunocompromised patients (B-cell chronic lymphocytic leukaemia and kidney graft associated with Hodgkin's disease) both had a favourable outcome complete cure their infectious endocarditis. This bacterium could be an emerging pathogen revealed by MALDI-TOF. Indeed, its characterisation within the group use biochemistry-based methods is...

10.4414/smw.2015.14185 article EN cc-by Schweizerische medizinische Wochenschrift 2015-09-16

We report the first proven case of osteomyelitis due to Erysipelothrix rhusiopathiae. This infection occurred almost 20 years after traumatic inoculation bacterium, when patient was gored by one his cows. Diagnosis made bone biopsies, and treatment included rifampicin levofloxacin for 3 months.

10.1016/j.ijid.2014.11.015 article EN cc-by-nc-nd International Journal of Infectious Diseases 2014-11-24
Pierre Fillâtre Alexandra Mailles J.‐P. Stahl Ronan Garlantézec Marion Le Maréchal and 95 more Pierre Tattevin Laurent Almoyna-Martinez Olivier Bouchaud T. de Broucker Fabrice Bruneel Bernard Castan É. Denes Olivier Épaulard Jean‐Louis Herrmann Jérôme Honnorat Alexandra Mailles Patrice Morand François Raffi F. Roblot J.‐P. Stahl Romain Sonneville Pierre Tattevin Sophie Abgrall Guillaume Baille Aurélie Baldolli K. Bertrand Julien Biberon Charlotte Biron Geneviève Blanchet-Fourcade Mathieu Blot Anne Bonnetain Elisabeth Botelho-Nevers D. Boutoille Hélène Brasme Cédric Bruel Rodolphe Buzelé Etienne Canouï Bernard Castan Charles Cazanave Céline Cazorla Thibault Challan-Belval P. Chavanet Catherine Chirouze Tomasz Chroboczek Johan Courjon T. de Broucker Arnaud De La Blanchardière Manuel Etienne É. Denes Aurélien Dinh Olivier Épaulard Pierre Fillâtre E. Forestier Amandine Gagneux-Brunon Nicolas Gaillard Julien Gautier François Goehringer Simon Gravier I. Gueït Thomas Guimard Carole Henry Jean-Étienne Herbrecht Fanny Jomier Snejana Jurici Solene Kerneis Jessica Krause Manuela Le Cam Marion Le Maréchal G. Le Moal Paul Le Turnier R. Lecomte Anne-Sophie Lecompte Romain Lefaucheur Olivier Lesieur P. Lesprit Guillaume Louis Rafaël Mahieu Alain Makinson Guillaune Marc A. Maria Nathalie Marin Guillaume Martin‐Blondel M. Martinot Alexandre Mas Philippe Mateu Laurence Maulin F. Méchaï Eugénie Mutez Jérémie Orain Anne Schieber-Pachart Nathalie Pansu S. Patrat-Delon Patricia Pavèse Hélène Pelerin Véronique Pelonde-Erimée Diane Ponscarme Mathilde Pugès Vincent Roubeau Yvon Ruch Isabelle Runge

10.1016/j.cmi.2024.11.001 article EN Clinical Microbiology and Infection 2024-11-01
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