- Advanced X-ray Imaging Techniques
- Advanced Electron Microscopy Techniques and Applications
- Microstructure and mechanical properties
- Advanced Neuroimaging Techniques and Applications
- Ferroelectric and Piezoelectric Materials
- Microstructure and Mechanical Properties of Steels
- Calcium Carbonate Crystallization and Inhibition
- Ichthyology and Marine Biology
- Bone Tissue Engineering Materials
- Electronic and Structural Properties of Oxides
- Machine Learning in Materials Science
- Paleontology and Stratigraphy of Fossils
- High-pressure geophysics and materials
- Advanced MRI Techniques and Applications
- Electron and X-Ray Spectroscopy Techniques
- Advancements in Solid Oxide Fuel Cells
- Magnetic Properties and Applications
- Paleontology and Evolutionary Biology
- Parkinson's Disease Mechanisms and Treatments
- Multiferroics and related materials
- Random lasers and scattering media
- Isotope Analysis in Ecology
- Nuclear Physics and Applications
- Geology and Paleoclimatology Research
- Functional Brain Connectivity Studies
European Synchrotron Radiation Facility
2017-2024
University of Leeds
2024
Danish Technological Institute
2024
University of Pennsylvania
2021-2024
BOKU University
2020-2023
Gregor Mendel Institute of Molecular Plant Biology
2021
Synchrotron soleil
2015-2018
Institut photonique d'analyse non-destructive européen des matériaux anciens
2015-2018
Mayo Clinic in Florida
2018
WinnMed
2018
Otolith chemistry has gained increasing attention as a tool for analyzing various aspects of fish biology, such stock dynamics, migration patterns, hypoxia and pollution exposure, connectivity between habitats. While these studies often assume otolith elemental concentrations reflect environmental conditions, physiological processes are increasingly recognized modulating and/or controlling factor. In particular, biomineralization—the complex, enzyme-regulated construction CaCO3 crystals...
Correlative neutron and X-ray imaging unravels the causes of localized defects in Li-ion batteries containing a silicon-graphite based anode.
A formalism is presented for dark-field X-ray microscopy using refractive optics. The new technique can produce three-dimensional maps of lattice orientation and axial strain within millimetre-sized sampling volumes particularly suited to in situ studies materials at hard energies. An objective lens the diffracted beam magnifies image acts as a very efficient filter reciprocal space, enabling imaging individual domains interest with resolution 100 nm. Analytical expressions optical...
Abstract We present an instrument for dark-field x-ray microscopy installed on beamline ID06 of the ESRF — first its kind. Dark-field uses full field illumination sample and provides three-dimensional (3D) mapping micro-structure lattice strain in crystalline matter. It is analogous to electron that objective lens magnifies diffracting features sample. The use high-energy synchrotron x-rays, however, means these can be large deeply embedded. 3D movies acquired with a time resolution seconds...
Abstract During cyclic loading, localization of intragranular deformation due to crystallographic slip acts as a precursor for crack initiation, often at coherent twin boundaries. A suite high-resolution synchrotron X-ray characterizations, coupled with crystal plasticity simulation, was conducted on polycrystalline nickel-based superalloy microstructure near parent-twin boundary in order understand the behavior this critical, 3D microstructural configuration. Dark-field microscopy spatially...
Dark-field X-ray microscopy movies reveal how patterns of microscopic defects in bulk aluminum destabilize from 97-99% melting.
A Python package for the analysis of dark-field X-ray microscopy (DFXM) and rocking curve imaging (RCI) data is presented. DFXM a non-destructive diffraction technique that provides three-dimensional maps lattice strain orientation. The darfix enables fast processing visualization these data, providing user with essential tools to extract information from acquired images in intuitive manner. These can be either imported as library components or accessed through graphical interface an Orange...
The progression of Parkinson's disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due the use heterogeneous methods small studies. Here we performed a large diffusion MRI study PD, integrating data from 17 cohorts worldwide, identify stage-specific profiles white matter differences. Diffusion-weighted 1654 participants diagnosed PD (age: 20–89 years; 33% female) 885...
Abstract Molluscan shells are a model system to understand the fundamental principles of mineral formation by living organisms. The diversity unconventional morphologies and 3D mineral–organic architectures that comprise these tissues, in combination with their exceptional mechanical efficiency, offers unique platform study formation–structure–function relationship biomineralized system. However, so far, morphogenesis ultrastructures is poorly understood. Here, comprehensive physical model,...
Dark-field X-ray microscopy is a new full-field imaging technique for nondestructively mapping the structure of deeply embedded crystalline elements in three dimensions. Placing an objective diffracted beam generates magnified projection image local volume. By placing detector back focal plane, high-resolution reciprocal space maps are generated Geometrical optics used to provide analytical expressions resolution and range associated field view sample plane. To understand effects coherence...
The structures, strain fields, and defect distributions in solid materials underlie the mechanical physical properties across numerous applications. Many modern microstructural microscopy tools characterize crystal grains, domains defects required to map lattice distortions or deformation, but are limited studies of (near) surface. Generally speaking, such cannot probe structural dynamics a way that is representative bulk behavior. Synchrotron X-ray diffraction based imaging has long mapped...
Nanometric particles of Co3[Fe(CN)6]2 magnetic cyano-bridged polymers have been synthesised by the combination direct synthesis mesoporous MSU-type silica and parallel reaction cobalt nitrate with potassium ferricyanide. This synthesis, relevant to integrative chemistry methods, allowed us confine particle growth during building mesostructured framework silica. The obtained composite materials were studied XRD, SAXS, TEM FT-IR. Magnetic measurements nanoparticles extracted after dissolution...
Crystallographic twins are critical to the properties of numerous materials from magnesium alloys piezoelectrics. Since onset twin formation is highly sensitive triaxial mechanical boundary conditions, non-destructive bulk microscopy techniques required. Elastic strains can be mapped via X-ray diffraction with a 100-200 nm resolution. However, interplay nanotwins cannot characterized. Here, method based on dark-field quantify density nanotwin variants lamellae sizes as small several tens...
Abstract Maps of dense subcellular features in biological tissue are the key to understanding structural basis organ function. Electron microscopy provides necessary resolution, yet - as electrons penetrate samples for only a few 100s nm requires physical sectioning or ablation, which strongly challenges anatomical investigations entire organs such mammalian brains. As demonstrated engineering and sciences, X-ray nanotomography represents promising alternative ultrastructural 3d imaging...
Abstract Background The progression of Parkinson’s disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due the use heterogeneous methods small studies, particularly regarding involvement white matter (WM) tracts. Here we performed largest diffusion MRI study PD date, integrating data from 17 cohorts worldwide, identify stage-specific profiles WM differences. Methods...
Synchrotron micro-scale X-ray absorption measurements and a mapping approach reveal homogeneous strontium chemical environment in archaeological modern fish otoliths.
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