Phil Cook

ORCID: 0000-0001-5714-4257
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About
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Research Areas
  • Advanced X-ray Imaging Techniques
  • Advanced Electron Microscopy Techniques and Applications
  • Microstructure and mechanical properties
  • Advanced Neuroimaging Techniques and Applications
  • Ferroelectric and Piezoelectric Materials
  • Microstructure and Mechanical Properties of Steels
  • Calcium Carbonate Crystallization and Inhibition
  • Ichthyology and Marine Biology
  • Bone Tissue Engineering Materials
  • Electronic and Structural Properties of Oxides
  • Machine Learning in Materials Science
  • Paleontology and Stratigraphy of Fossils
  • High-pressure geophysics and materials
  • Advanced MRI Techniques and Applications
  • Electron and X-Ray Spectroscopy Techniques
  • Advancements in Solid Oxide Fuel Cells
  • Magnetic Properties and Applications
  • Paleontology and Evolutionary Biology
  • Parkinson's Disease Mechanisms and Treatments
  • Multiferroics and related materials
  • Random lasers and scattering media
  • Isotope Analysis in Ecology
  • Nuclear Physics and Applications
  • Geology and Paleoclimatology Research
  • Functional Brain Connectivity Studies

European Synchrotron Radiation Facility
2017-2024

University of Leeds
2024

Danish Technological Institute
2024

University of Pennsylvania
2021-2024

BOKU University
2020-2023

Gregor Mendel Institute of Molecular Plant Biology
2021

Synchrotron soleil
2015-2018

Institut photonique d'analyse non-destructive européen des matériaux anciens
2015-2018

Mayo Clinic in Florida
2018

WinnMed
2018

Otolith chemistry has gained increasing attention as a tool for analyzing various aspects of fish biology, such stock dynamics, migration patterns, hypoxia and pollution exposure, connectivity between habitats. While these studies often assume otolith elemental concentrations reflect environmental conditions, physiological processes are increasingly recognized modulating and/or controlling factor. In particular, biomineralization—the complex, enzyme-regulated construction CaCO3 crystals...

10.1080/23308249.2020.1760204 article EN Reviews in Fisheries Science & Aquaculture 2020-06-01
Azeez Adebimpe Maxwell A. Bertolero Sudipto Dolui Matthew Cieslak Kristin Murtha and 95 more Erica B. Baller Bradley F. Boeve Adam L. Boxer Ellyn R. Butler Phil Cook Stan Colcombe Sydney Covitz Christos Davatzikos Diego Davila Mark A. Elliott Matthew W. Flounders Alexandre R. Franco Raquel E. Gur Ruben C. Gur Basma Jaber Corey McMillian Liana G. Apostolova Brian S. Appleby Sami J. Barmada Yvette Bordelon Hugo Botha Adam L. Boxer Andrea Bozoki Danielle Brushaber David A. Clark Giovanni Coppola Ryan Darby Dennis W. Dickson Kimiko Domoto‐Reilly Kelley Faber Anne M. Fagan Julie A. Fields Tatiana M. Foroud Leah K. Forsberg Daniel H. Geschwind Jill Goldman Douglas Galasko Ralitza H. Gavrilova Tania F. Gendron Jonathon Graff-Radford Neill R. Graff‐Radford Ian Grant Murray Grossman Matt Hall Eric J. Huang Hilary W. Heuer Ging‐Yuek Robin Hsiung Edward D. Huey David J. Irwin David T. Jones Kejal Kantarci Daniel Kaufer Diana Kerwin David S. Knopman John Kornak Joel H. Kramer Walter K. Kremers Maria I. Lapid Argentina Lario Lago Gabriel C. Léger Peter A. Ljubenkov Irene Litvan Diane Lucente Ian R. Mackenzie Joseph C. Masdeu Scott McGinnis Mario F. Mendez Carly T. Mester Bruce L. Miller Chiadi U. Onyike M. Belen Pascual Leonard Petrucelli Peter Pressman Rosa Rademakers Vijay K. Ramanan Eliana Marisa Ramos Meghana Rao Katya Rascovsky Katherine P. Rankin Aaron Ritter Erik D. Roberson Julio Rojas-Martinez Howard J. Rosen Rodolfo Savica William W. Seeley Jeremy A. Syrjanen Adam M. Staffaroni Maria Carmela Tartaglia Jack A. Taylor Lawren VandeVrede Sandra Weıntraub Bonnie Wong Zbigniew K. Wszołek Michael P. Milham Henk J. M. M. Mutsaerts

10.1038/s41592-022-01458-7 article EN Nature Methods 2022-06-01

Correlative neutron and X-ray imaging unravels the causes of localized defects in Li-ion batteries containing a silicon-graphite based anode.

10.1039/d4ee00590b article EN cc-by-nc Energy & Environmental Science 2024-01-01

A formalism is presented for dark-field X-ray microscopy using refractive optics. The new technique can produce three-dimensional maps of lattice orientation and axial strain within millimetre-sized sampling volumes particularly suited to in situ studies materials at hard energies. An objective lens the diffracted beam magnifies image acts as a very efficient filter reciprocal space, enabling imaging individual domains interest with resolution 100 nm. Analytical expressions optical...

10.1107/s1600576717011037 article EN Journal of Applied Crystallography 2017-09-25

Abstract We present an instrument for dark-field x-ray microscopy installed on beamline ID06 of the ESRF — first its kind. Dark-field uses full field illumination sample and provides three-dimensional (3D) mapping micro-structure lattice strain in crystalline matter. It is analogous to electron that objective lens magnifies diffracting features sample. The use high-energy synchrotron x-rays, however, means these can be large deeply embedded. 3D movies acquired with a time resolution seconds...

10.1088/1757-899x/580/1/012007 article EN IOP Conference Series Materials Science and Engineering 2019-08-01

Abstract During cyclic loading, localization of intragranular deformation due to crystallographic slip acts as a precursor for crack initiation, often at coherent twin boundaries. A suite high-resolution synchrotron X-ray characterizations, coupled with crystal plasticity simulation, was conducted on polycrystalline nickel-based superalloy microstructure near parent-twin boundary in order understand the behavior this critical, 3D microstructural configuration. Dark-field microscopy spatially...

10.1038/s41467-020-16894-2 article EN cc-by Nature Communications 2020-06-24

Dark-field X-ray microscopy movies reveal how patterns of microscopic defects in bulk aluminum destabilize from 97-99% melting.

10.1126/sciadv.abe8311 article EN cc-by-nc Science Advances 2021-07-14

A Python package for the analysis of dark-field X-ray microscopy (DFXM) and rocking curve imaging (RCI) data is presented. DFXM a non-destructive diffraction technique that provides three-dimensional maps lattice strain orientation. The darfix enables fast processing visualization these data, providing user with essential tools to extract information from acquired images in intuitive manner. These can be either imported as library components or accessed through graphical interface an Orange...

10.1107/s1600577523001674 article EN cc-by Journal of Synchrotron Radiation 2023-03-31

The progression of Parkinson's disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due the use heterogeneous methods small studies. Here we performed a large diffusion MRI study PD, integrating data from 17 cohorts worldwide, identify stage-specific profiles white matter differences. Diffusion-weighted 1654 participants diagnosed PD (age: 20–89 years; 33% female) 885...

10.1038/s41531-024-00758-3 article EN cc-by-nc-nd npj Parkinson s Disease 2024-08-11

Abstract Molluscan shells are a model system to understand the fundamental principles of mineral formation by living organisms. The diversity unconventional morphologies and 3D mineral–organic architectures that comprise these tissues, in combination with their exceptional mechanical efficiency, offers unique platform study formation–structure–function relationship biomineralized system. However, so far, morphogenesis ultrastructures is poorly understood. Here, comprehensive physical model,...

10.1002/adma.201803855 article EN Advanced Materials 2018-09-21

Dark-field X-ray microscopy is a new full-field imaging technique for nondestructively mapping the structure of deeply embedded crystalline elements in three dimensions. Placing an objective diffracted beam generates magnified projection image local volume. By placing detector back focal plane, high-resolution reciprocal space maps are generated Geometrical optics used to provide analytical expressions resolution and range associated field view sample plane. To understand effects coherence...

10.1107/s1600576718011378 article EN Journal of Applied Crystallography 2018-09-13

The structures, strain fields, and defect distributions in solid materials underlie the mechanical physical properties across numerous applications. Many modern microstructural microscopy tools characterize crystal grains, domains defects required to map lattice distortions or deformation, but are limited studies of (near) surface. Generally speaking, such cannot probe structural dynamics a way that is representative bulk behavior. Synchrotron X-ray diffraction based imaging has long mapped...

10.1038/s41598-023-35526-5 article EN cc-by Scientific Reports 2023-10-16

Nanometric particles of Co3[Fe(CN)6]2 magnetic cyano-bridged polymers have been synthesised by the combination direct synthesis mesoporous MSU-type silica and parallel reaction cobalt nitrate with potassium ferricyanide. This synthesis, relevant to integrative chemistry methods, allowed us confine particle growth during building mesostructured framework silica. The obtained composite materials were studied XRD, SAXS, TEM FT-IR. Magnetic measurements nanoparticles extracted after dissolution...

10.1039/b9nj00271e article EN New Journal of Chemistry 2009-01-01

Crystallographic twins are critical to the properties of numerous materials from magnesium alloys piezoelectrics. Since onset twin formation is highly sensitive triaxial mechanical boundary conditions, non-destructive bulk microscopy techniques required. Elastic strains can be mapped via X-ray diffraction with a 100-200 nm resolution. However, interplay nanotwins cannot characterized. Here, method based on dark-field quantify density nanotwin variants lamellae sizes as small several tens...

10.1016/j.scriptamat.2021.113878 article EN cc-by Scripta Materialia 2021-03-29

Abstract Maps of dense subcellular features in biological tissue are the key to understanding structural basis organ function. Electron microscopy provides necessary resolution, yet - as electrons penetrate samples for only a few 100s nm requires physical sectioning or ablation, which strongly challenges anatomical investigations entire organs such mammalian brains. As demonstrated engineering and sciences, X-ray nanotomography represents promising alternative ultrastructural 3d imaging...

10.1101/2023.11.16.567403 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2023-11-17

Abstract Background The progression of Parkinson’s disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due the use heterogeneous methods small studies, particularly regarding involvement white matter (WM) tracts. Here we performed largest diffusion MRI study PD date, integrating data from 17 cohorts worldwide, identify stage-specific profiles WM differences. Methods...

10.1101/2024.01.16.24301235 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-01-17

Synchrotron micro-scale X-ray absorption measurements and a mapping approach reveal homogeneous strontium chemical environment in archaeological modern fish otoliths.

10.1039/c5ja00426h article EN Journal of Analytical Atomic Spectrometry 2015-12-23

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10.1017/s1431927618012837 article EN Microscopy and Microanalysis 2018-08-01
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