A5063451370- Colorectal Cancer Surgical Treatments
- Minimally Invasive Surgical Techniques
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- Diverticular Disease and Complications
- Hernia repair and management
- Cardiac, Anesthesia and Surgical Outcomes
- Enhanced Recovery After Surgery
- Colorectal and Anal Carcinomas
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Screening and Detection
- Chronic Lymphocytic Leukemia Research
- Genetics, Bioinformatics, and Biomedical Research
- Tribology and Wear Analysis
- Cancer-related Molecular Pathways
- Genomics and Phylogenetic Studies
- Surgical Simulation and Training
- Cancer-related gene regulation
- Angiogenesis and VEGF in Cancer
- ECG Monitoring and Analysis
- Extracellular vesicles in disease
- IoT and Edge/Fog Computing
- Machine Learning in Bioinformatics
- Cancer Immunotherapy and Biomarkers
- Context-Aware Activity Recognition Systems
Ruijin Hospital
2018-2024
Shanghai Jiao Tong University
2018-2024
Corvid Technologies (United States)
2023
American Society of Anesthesiologists
2023
Total (France)
2023
Quality of Life Research Center
2023
European Organisation for Research and Treatment of Cancer
2023
Chongqing Electromechanical Holdings (China)
2023
Robotic Technology (United States)
2023
Harbin Institute of Technology
2022
Nirmatrelvir-ritonavir has been authorized for emergency use by many countries the treatment of coronavirus disease 2019 (Covid-19). However, supply falls short global demand, which creates a need more options. VV116 is an oral antiviral agent with potent activity against severe acute respiratory syndrome 2 (SARS-CoV-2).We conducted phase 3, noninferiority, observer-blinded, randomized trial during outbreak caused B.1.1.529 (omicron) variant SARS-CoV-2. Symptomatic adults mild-to-moderate...
Leukemia inhibitory factor receptor (LIFR) has been documented as a cancer promoter and to be present at high levels in various types of tumor tissues. In our search for molecules prognostic colorectal (CRC), we found LIFR CRC tissue samples. Further analyses revealed that was indeed patient survival, associated with size, lymphatic metastasis stages. promote growth, angiogenesis both vitro vivo. High facilitated proliferation migration endothelial cells, resulting an increase angiogenic...
The technological barriers and steep learning curve of single-incision laparoscopic surgery had kept it from further applications. A literature review reported that robotic technology could preserve its advantages while simplifying difficulties. This nonrandomized cohort pilot study aims to evaluate the feasibility safety assisted colorectal based on a novel surgical platform, SHURUI Endoscopic Surgical Robotic System (SR-ENS-600).This enrolled 7 patients with malignancy who underwent...
Metagenomic data, comprising mixed multi-species genomes, are prevalent in diverse environments like oceans and soils, significantly impacting human health ecological functions. However, current research relies on K-mer representations, limiting the capture of structurally relevant gene contexts. To address these limitations further our understanding complex relationships between metagenomic sequences their functions, we introduce a protein-based representation as context-aware...
Abstract E26 transformation-specific variant transcription factor 5 (ETV5) contributes to tumor growth and progression promotes colorectal cancer (CRC) angiogenesis. Previous studies indicate that ETV5 may regulate the cell cycle, but its detailed mechanism remain unclear. Gene Ontology (GO) analysis of RNA-seq data revealed possibly regulates cycle in CRC. Here, vitro vivo experiments were performed verify promoted influenced G1/S transition. Cell PCR array co-immunoprecipitation (Co-IP)...
Recently, enhanced recovery after surgery (ERAS) has been widely used in the perioperative management of colorectal cancer (CRC). This study aimed to evaluate safety and feasibility ERAS combined with single-incision laparoscopic (SILS) CRC surgery.This was a retrospective patients who underwent between April 2018 2020 Ruijin Hospital(North), Shanghai Jiaotong University School Medicine. The were divided into three groups: group A (n=138), traditional multiport colectomy conventional...
Abstract Background In most previous studies, single-incision laparoscopic surgery (SILS) for colorectal cancer (CRC) was feasible and safe in the short term. However, long-term oncologic outcomes remain uncertain, as only a few studies contained survival data. SILS CRC is still early stages of research. Further particularly large-scale, prospective randomized controlled trials, are necessary to assess value CRC. Methods This study prospective, multicentre, open-label, noninferiority,...
Pure transvaginal natural orifice transluminal endoscopic surgery right hemicolectomy for colon cancer: A case report
Purpose: The aim of this study is to compare the short-term and pathological outcomes TPLRC (Three-port laparoscopic right hemicolectomy) FPLRC (Five-port hemicolectomy), using propensity score matching analysis. Methods: One hundred sixty-eight patients who accepted hemicolectomy with either three ports or five from January 2013 October 2017 were non-randomly selected analyzed retrospectively. Propensity model was used eliminate patients' selection bias between two groups. Results: A total...
To date, well-designed randomized controlled trials examining the safety, efficacy, and long-term outcomes of single-incision laparoscopic surgery (SILS) for colorectal cancer are scarce. The aim current study was to compare short-term SILS with conventional (CLS).Between June 28, 2017, 29, 2019, a single-center, open-label, non-inferiority, clinical trial conducted at Department General Surgery, Ruijin Hospital (North), Shanghai Jiaotong University School Medicine in Shanghai, China. In...
The aim of this study is to compare the long-term outcomes three-port laparoscopic right hemicolectomy (TPLRC) and five-port (FPLRC) with retrospective analysis.A total 182 patients who accepted either three ports (86 patients) or five (96 from January 2012 June 2017 were non-randomly selected analyzed retrospectively.More lymph nodes harvested in TPLRC group than FPLRC [17.5 (7), 14 (8) ml, p < 0.001]. There was less blood loss [50 (80) vs. 100 (125) = 0.015]. no significant differences...
Multimodal fusion breaks through the barriers between diverse modalities and has already yielded numerous impressive performances. However, in various specialized fields, it is struggling to obtain sufficient alignment data for training process, which seriously limits use of previously elegant models. Thus, semi-supervised learning attempts achieve multimodal with fewer matched pairs but traditional methods like pseudo-labeling are difficult apply domains no label information. To address...
<title>Abstract</title> Background Tumor metastasis has been regarded as the leading risk factor for tumor patients. BEN-domain (BEND) family proteins have not well elucidated in metastasis. Methods To uncover roles of BEND (BEND2-7) colorectal cancer (CRC), we first mined their mRNA expression both and normal tissues from CRC patients, plotted survival curve. Through <italic>in vitro</italic> cell migration, invasion vivo</italic> experiments, confirmed that BEND3 acted a suppressor by...
Abstract Background Anti‐PD1/PD‐L1 antibody plus human epidermal growth factor receptor 2 (HER2) and chemotherapy have become the new first‐line therapy for HER2 overexpression‐positive advanced gastric cancers (GC), suggesting that PD‐L1 play a vital role in guiding systemic treatment patients with GC. This study aimed to depict genomic immune landscapes of Chinese GC investigate their correlations amplification expression. Patients Methods Next‐generation targeted sequencing...
Splenic flexure cancer (SFC) is a rare condition in colorectal (CRC). The appropriate surgical treatment for SFC remains controversial. In recent years, we have used artery-guided segmental splenic colectomy (ASFC) to treat which robotic access gradually applied. study sought assess the clinical and oncologic outcomes of robotic-assisted ASFC compared laparoscopic-assisted by undertaking propensity score-matching analysis.Seventy patients underwent (n=19) or (n=51) from Dec 2015 2019. Their...
Background: The aim of this study was to compare the short and long-term outcomes robotic assisted proctectomy (RP) laparoscopic (LP) for rectal cancer below peritoneal reflection using propensity score matching (PSM) analysis. Methods:We evaluated medical records 200 patients who underwent through a (n=81) or (n=119) approach between Jan 2015 Dec 2017.The data were prospectively collected, matched at ratio 1:1 according age, sex, body mass index (BMI), previous abdominal surgeries,...