A5043643956- Growth Hormone and Insulin-like Growth Factors
- Pituitary Gland Disorders and Treatments
- Bone health and treatments
- Bone health and osteoporosis research
- Diet and metabolism studies
- LGBTQ Health, Identity, and Policy
- Adrenal and Paraganglionic Tumors
- Thyroid Disorders and Treatments
- Neuroendocrine Tumor Research Advances
- Hormonal and reproductive studies
- Estrogen and related hormone effects
- Sexual Differentiation and Disorders
- Adrenal Hormones and Disorders
- Scoliosis diagnosis and treatment
- Bone Metabolism and Diseases
- Cerebrovascular and Carotid Artery Diseases
- Genetic Syndromes and Imprinting
- Ophthalmology and Eye Disorders
- Lipid metabolism and disorders
- Male Breast Health Studies
- COVID-19 and healthcare impacts
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- BRCA gene mutations in cancer
- Vitamin D Research Studies
- Hemoglobinopathies and Related Disorders
IRCCS Istituto Auxologico Italiano
2001-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2025
University of Milan
2001-2021
University of Brescia
2001-2009
Inserm
2009
Université Paris-Sud
2009
Brescia University
2003-2004
Ospedale San Giuseppe
2001
IRCCS Ospedale San Raffaele
2001
Context: The term primary empty sella (PES) refers to a number of endocrine and/or neurological disturbances that may be caused by the herniation subarachnoid space within sella. Setting: records all patients with diagnosis between 1985 and 2002 seen at Catholic University Rome Brescia were examined retrospectively. Patients: We have observed 171 female 42 male affected PES (over 4:1 sex ratio). mean age in our subjects was 51.8 ± 2.1 yr. Mean body mass index 27.3 3.5 kg/m2. Main Outcome...
This cross-sectional study shows that high numbers of postmenopausal women with acromegaly develop vertebral fractures in relation to the activity disease. In patients active acromegaly, occur even presence normal BMD, whereas controlled are always accompanied by a pathological BMD.We studied frequency radiological cohort or acromegaly.Thirty-six acromegalic (15 and 21 disease) were evaluated for bone metabolism (serum 25-hydroxyvitamin D, PTH, bone-specific alkaline phosphatase [BSALP],...
Data on osteoporotic fractures in acromegaly are limited. An increased prevalence of radiological vertebral was already observed postmenopausal women with active acromegaly. It is unknown whether this observation may reflect a more general risk acromegaly.This cross-sectional study.The study conducted at referral centers.Subjects included 40 males (25 patients controlled disease and 15 disease) 31 control males, age gonadal status comparable the patients.Evaluation (quantitative morphometric...
Objective Isolated hypogonadotropic hypogonadism (IHH) is a rare disorder with pubertal delay, normal (normoosmic-IHH, nIHH) or defective sense of smell (Kallmann syndrome, KS). Other reproductive and non-reproductive anomalies might be present although information on their frequency are scanty, particularly according to the age presentation. Design Observational cohort study carried out between January 2008 June 2016 within national network academic general hospitals. Methods We performed...
The COVID-19 pandemic caused an increased mortality in nursing homes due to its quick spread and the age-related high lethality.We observed a two-month of 40%, compared 6.4% previous year. This increase was seen both positive (43%) negative (24%) residents, but 8 patients among those testing on swab, tested serological tests. Increased associated with male gender, older age, no vitamin D supplementation worse "activities daily living (ADL)" scores, such as Barthel index, Tinetti scale...
Abstract This cross-sectional study shows that a high number of untreated adult patients with GHD develop radiological vertebral deformities. Patients undergoing GH replacement treatment showed significantly lower prevalence deformities versus treated in the presence similar BMD, as assessed by DXA. Introduction: In this study, we investigated whether and degree spinal adults growth hormone deficiency (GHD) were related to age patients, bone turnover, recombinant human (rhGH) therapy....
Objective In acromegaly, 25–50% of patients respond inadequately to conventional long-acting somatostatin analogue (SSA) therapy. Response may be improved by increasing SSA frequency or dose. This study evaluated the biochemical efficacy and safety high-dose octreotide in with acromegaly. Design A 24-week prospective, multicentre, randomised, open-label trial conducted from 12 December 2005 23 October 2007 persistently uncontrolled acromegaly despite ≥6 month Methods Patients ≥50% reduction...
Objective : Spontaneous parathyroid hormone (PTH) secretory dynamics include tonic and pulsatile components. It is not known how glucocorticoids might alter these dynamics. Design The aim of our study was to evaluate spontaneous fluctuations in serum PTH levels six adult male patients (aged 31–64 years) receiving chronic (>6 months) therapy with (daily dosage >7.5 mg prednisone or dose equivalent other corticosteroid) as compared a control group 10 age- sex-matched normal subjects....
Treatment of osteoporosis is aimed to prevent fragility fractures and stabilize or increase bone mineral density. Several drugs with different efficacy safety profiles are available. The long-term therapeutic strategy should be planned, the initial treatment selected according individual site-specific fracture risk need give maximal protection when highest (i.e. in late life). present consensus focused on strategies for postmenopausal taking into consideration all available this purpose. A...
Structural alterations of small resistance arteries in patients with essential hypertension (EH) are mostly characterized by inward eutrophic remodeling. However, we have observed the presence hypertrophic remodeling renovascular hypertension, as well noninsulin-dependent diabetes mellitus, suggesting a relevant effect humoral growth factors on vascular structure. Growth hormone may stimulate vitro proliferation smooth muscle cells. no data presently available about artery structure...
Transgender and gender-diverse (TGD) individuals continue to experience harassment discrimination across various aspects of life, significantly impacting their physical mental health. The scarcity data on general health, particularly regarding dietary habits, remains a challenge in developing effective healthcare strategies for this population. To address gap, we analyzed selected activity (PA), body mass index (BMI) among Italian TGD adults compared the population (IGP). An online anonymous...