A5101931858- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Cervical and Thoracic Myelopathy
- Liver Disease and Transplantation
- Network Traffic and Congestion Control
- Chaos control and synchronization
- Medical Imaging and Analysis
- Mitochondrial Function and Pathology
- Neuroscience and Neuropharmacology Research
- Economic and Technological Developments in Russia
- Anatomy and Medical Technology
- Reconstructive Surgery and Microvascular Techniques
- Cancer, Lipids, and Metabolism
- MicroRNA in disease regulation
- Retinal Diseases and Treatments
- Organ Transplantation Techniques and Outcomes
- Neonatal and fetal brain pathology
- Mobile Agent-Based Network Management
- Mathematical Dynamics and Fractals
- Heterotopic Ossification and Related Conditions
- Chaos-based Image/Signal Encryption
- Retinal Imaging and Analysis
- IPv6, Mobility, Handover, Networks, Security
- Network Security and Intrusion Detection
Peking University
2019-2024
Peking University Third Hospital
2020-2024
Ministry of Education of the People's Republic of China
2005-2024
China Electric Power Research Institute
2023-2024
North China Electric Power University
2023-2024
Anhui Medical University
2024
Tsinghua–Berkeley Shenzhen Institute
2024
Tsinghua University
2024
Jilin University
2022-2023
Jilin Province Science and Technology Department
2022
Vascular remodeling plays a key role in neural regeneration the injured brain. Circulating endothelial progenitor cells (EPCs) are mediator of vascular process. Previous studies have found that progesterone treatment traumatic brain injury (TBI) decreases cerebral edema and cellular apoptosis inhibits inflammation, which concert promote neuroprotective effects young adult rats. However, whether regulates circulating EPC level fosters after TBI not been investigated. In this study, we...
Oxeiptosis is a reactive oxygen species (ROS)-induced pathway of cell death. The involvement circular RNAs (circRNAs) has been confirmed in the incidence and progression intervertebral disc degeneration (IVDD). However, whether oxeiptosis occurs IVDD how circRNAs regulate still unclear. In this study, we discovered that could be induced nucleus pulposus cells (NPCs), circFOXO3 was significantly upregulated after induction. Transfection using small interfering RNA (siRNA) inhibited NPCs....
Background Stroke is a pressing public health issue worldwide. This study aimed to forecast the future temporal trends and distribution characteristics of global stroke burden. Methods Results Global data on incidence, prevalence, deaths, disability‐adjusted life years between 1990 2021 were obtained from GBD (Global Burden Disease) Study 2021. The burden estimated using various regression models. Gross domestic product per capita was adopted as predictor in model consider impact economic...
Background Ossification of ligamentum flavum (OLF) is an insidious and debilitating heterotopic ossifying disease with etiological heterogeneity undefined pathogenesis. Obese individuals predispose to OLF, whereas the underlying connections between obesity phenotype OLF pathomechanism are not fully understood. Therefore, this study aims explore distinct obesity-related genes their functional signatures in OLF. Methods The transcriptome sequencing data related were downloaded from GSE106253...
Abstract To harness the advantages of both proactive and responsive scaling, adapting to various workload scenarios, this paper introduces a container hybrid scaling strategy called HyPredRL, rooted in load prediction reinforcement learning. Within module RL-PM, model, MSC-LSTM, predict workloads and, conjunction with current states, leverages learning agents for intelligent decisions. The strategy, SLA-HPA, enhances Kubernetes’ native which primarily considers resource utilization, by...
Background Traumatic brain injury (TBI) is a heterogeneous condition that can lead to critical LLLness-related corticosteroid insufficiency (CIRCI) causing high mortality and morbidity. Glucocorticoids were widely used in the clinical management of TBI, but their benefit has been challenged some studies efficacy, especially for treating CIRCI TBI patients, remains unclear. Methods We conducted meta-analysis published data determine if controversy related dosing timing glucocorticoids (GCs)...
Traumatic brain injury can cause loss of neuronal tissue, remote symptomatic epilepsy, and cognitive deficits. However, the mechanisms underlying effects traumatic are not yet clear. Hippocampal excitability is strongly correlated with dysfunction epilepsy. In this study, we examined relationship between injury-induced subsequent hippocampal regional excitability. We used hydraulic percussion to generate a rat model injury. At 7 days after injury, mean modified neurological severity score...
Background: Ossification of the ligamentum flavum (OLF) is most common cause thoracic spinal stenosis, which responds poorly to conservative treatment. Thus, surgery only effective treatment for OLF. The existence dural ossification (DO) makes challenging and increases risk intra-/post-operative complications. To date, several methods have been proposed identify DO, but either diagnostic accuracy low or feasibility poor. Therefore, aim this study was propose a new imaging sign (Banner cloud...
To solve the problem of automatic grading macular edema in retinal images a more stable and reliable way reduce workload ophthalmologists, an detection method diabetic based on deep neural network is proposed.The enhanced green channels fundus are input into YOLO for training testing. Diabetic graded according to distance macula hard exudate. We used multiscale feature fusion form comprehensive features different grain improve effect exudate detection. adopted K-means++ algorithm cluster...
Data about minimally invasive surgery for the treatment of patients with degenerative disc disease (DDD) has been reported. However, no quantitative knowledge biomechanical characteristics spinous processes in DDD after operation was reported literature. Fourteen adult at L3-4 level were recruited and scanned using computed tomography (CT) to construct three-dimensional (3D) anatomical vertebral models L2-5. These asked maintain four positions acquire 6DOF data area spine being investigated...
Objective The aim of the present paper was to evaluate strength and magnitude association between ossification nuchal ligament (ONL) risk cervical posterior longitudinal (COPLL) determine whether there is a direct or COPLL consequence shared factors. Methods Medline, Web Science, Cochrane Library, Embase databases were searched for studies evaluating COPLL‐ONL published before July 2020. Eligible selected based on certain inclusion exclusion criteria. Two investigators independently...
ABSTRACT Nonalcoholic fatty liver disease (NAFLD) is a prevalent disorder affecting approximately 25.2% of the global population, posing risks fibrosis, cancer, and metabolic disturbances. Despite its increasing prevalence, many facets NAFLD's pathogenesis remain elusive, there are currently no approved therapeutic drugs, underscoring critical need for comprehensive understanding pathophysiology to enable early diagnosis intervention. Experimental animal studies play pivotal role in...