- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Moyamoya disease diagnosis and treatment
- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Pancreatitis Pathology and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Vascular Malformations Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Phagocytosis and Immune Regulation
- HIV Research and Treatment
- Cardiac Arrhythmias and Treatments
- Heart Rate Variability and Autonomic Control
- Renin-Angiotensin System Studies
- Cardiac tumors and thrombi
- Vagus Nerve Stimulation Research
- Inflammasome and immune disorders
- Neurofibromatosis and Schwannoma Cases
- Endometriosis Research and Treatment
- RNA Research and Splicing
- Myasthenia Gravis and Thymoma
- Cardiovascular Health and Disease Prevention
- Thermal Regulation in Medicine
- Erythropoietin and Anemia Treatment
- Endometrial and Cervical Cancer Treatments
Huazhong University of Science and Technology
2024-2025
Tongji Hospital
2024-2025
Third People's Hospital of Huzhou
2024
Sichuan University
2024
West China Hospital of Sichuan University
2024
Hangzhou Xixi hospital
2020-2024
Huzhou University
2024
West China Medical Center of Sichuan University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Air Force Medical University
2009-2022
Prior randomized trials have generally shown harm or no benefit of stenting added to medical therapy for patients with symptomatic severe intracranial atherosclerotic stenosis, but it remains uncertain as whether refined patient selection and more experienced surgeons might result in improved outcomes.To compare plus vs alone stenosis.Multicenter, open-label, randomized, outcome assessor-blinded trial conducted at 8 centers China. A total 380 transient ischemic attack nondisabling,...
We identified the timing of natural involution acute retinopathy prematurity (ROP) not requiring treatment and determined risk factors associated with delayed involution.In this retrospective case series, 82 eyes (the more severe eye) infants who developed at least one clock hour ROP, stages 1 through 3, but didn't progress to type were selected for analysis. The location, extent, severity ROP documented by investigators during serial retinal examinations. onset completion ROP's from a...
Background and Purpose: As a rare lesion secondary to brain trauma, traumatic intracranial aneurysms (TICAs) lead high mortality morbidity, multiple treatment modalities have been applied for TICAs. All patients diagnosed with TICAs in our institution from 2010 2020 were included the report, their clinical features, treatment, outcomes are described detail. The purpose of this study is illustrate characteristic different therapeutic methods TICAs, focus on endovascular treatment. Methods: A...
Objectives The cholinergic anti-inflammatory pathway has been elucidated as a regulator of inflammatory responses in several experimental models diseases. This regulatory mechanism is mediated by acetylcholine, released from efferent vagus nerve, interacts with α7 nicotinic acetylcholine receptors on immune cells. Experimental evidence indicates that nerve stimulation or receptor agonists control proinflammatory cytokine production and protect animals diverse lethal models. aim the study was...
To establish a rat model of acute pancreatitis in pregnancy (APIP) and evaluate its general presentations, assess placental injury, discuss possible mechanisms.The APIP was induced by sodium taurocholate Sprague-Dawley rats later gestation. Normal sham-operated (SO) gestation were set as controls, 3 time points SO groups to determine optimal modeling time. Histological changes pancreas placenta assessed. Placental injury determined immunohistochemistry stain caspase-3. Serum levels amylase,...
Efferocytosis of apoptotic neutrophils (PMNs) by macrophages is helpful for inflammation resolution and injury repair, but the role efferocytosis in intrinsic nature during septic acute kidney (AKI) remains unknown. Here we report that CD47 signal regulatory protein alpha (SIRPα)-the anti-efferocytotic 'don't eat me' signals-are highly expressed peripheral blood mononuclear cells (PBMCs) from patients with AKI samples mice polymicrobial sepsis endotoxin shock. Conditional knockout (CKO)
Abstract Background Atrial fibrillation (AF) is highly correlated with heart failure, stroke and death. Screening increases AF detection facilitates the early adoption of comprehensive intervention. Long-term wearable devices have become increasingly popular for screening in primary care. However, interpreting data obtained by long-term ECG a problem To diagnose disease quickly accurately, we aimed to build episode model based on nonlinear Lorenz scattergram (LS) deep learning. Methods The...
The assay was used in HIV/AIDS surveillance sentinel sites to identify recent HIV-1 infection, estimate incidence and understand the epidemic trends among men who have sex with during 2011-2015. During 2011-2015, of 5.16%(95%CI: 4.65%-5.66%) Sichuan Province. According to<Pilot study on classification criteria AIDS China>, a total 9 cities had been divided into two type regions: first type(the proportion live accounts for more than 0.1% permanent population, number has reached 500 cases...
Objective To evaluate the effectiveness of Willis covered stent (WCS) in treatment ruptured blood blister-like aneurysms (BBAs) internal carotid artery (ICA). Method The clinical data 16 patients consecutively treated with WCSs from December 2015 to January 2019 were retrospectively analyzed. Clinical and angiographic findings analyzed by two experienced neuroradiologists neurosurgeons, including age, sex, Hunt Hess (H&amp;H) grade at admission, modified Rankin scale (mRS) score,...
Ischemic stroke combined with hypertension can increase risks of recurrence and death.The aim this study is to investigate the clinical efficacy clopidogrel bisulfate tablets olmesartan medoxomil in treatment ischemic patients effect angiotensin II type 1 receptor (AT1R) level on prognosis.Ninety were chosen for continuous 12 months. The Modified Edinburgh Scandinavian Stroke Scale (MESSS) score, Brunnstrom Barthel death, recurrence, progression cerebrovascular residual lesions observed...
Background More data is needed on the short- and medium-term efficacy safety of Willis covered stent in treating distal internal carotid artery (DICA) aneurysms vertebral dissecting (VADAs). Methods Records all 42 patients with DICA or VADAs treated stents at our institute between July 2014 January 2019 were retrospectively examined. The patients’ demographic information, symptoms, diagnosis, treatment procedure, immediate follow-up clinical angiographic outcomes extracted. Results 46...
Objective: To evaluate the influence of antiretroviral prophylaxis on growth and development HIV-exposed uninfected infants in Guangzhou. Methods: Data were from national information system for prevention mother-to-child transmission HIV infection, syphilis hepatitis B. After excluding death perinatal infection cases, 564 included. The divided into three groups, nevirapine (NVP) group, zidovudine (AZT) group untreated group. influences body weight height analyzed by using generalized...
The drug instructions for dabigatran recommend adjusting the dosage to 110 mg twice daily patients with bleeding risk, and performing at least one renal function test per year moderate impairment. However, owing chronic insidiously worsening insufficiency, can still accumulate abnormally, necessitating therapy idarucizumab reverse anticoagulation due severe erosive gastritis widespread stomach mucosal bleeding.A 76-year-old woman a history of atrial fibrillation who took as directed lessen...