A5101622922- Infant Nutrition and Health
- Congenital gastrointestinal and neural anomalies
- Neonatal Respiratory Health Research
- Fetal and Pediatric Neurological Disorders
- Cancer Cells and Metastasis
- Cerebrospinal fluid and hydrocephalus
- Congenital Anomalies and Fetal Surgery
- Advanced Neuroimaging Techniques and Applications
- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Neuroinflammation and Neurodegeneration Mechanisms
- Intensive Care Unit Cognitive Disorders
- Advanced Photocatalysis Techniques
- Autophagy in Disease and Therapy
- Child Nutrition and Feeding Issues
- Liver physiology and pathology
- Liver Disease Diagnosis and Treatment
- Metal-Organic Frameworks: Synthesis and Applications
- Immune cells in cancer
- Pancreatic and Hepatic Oncology Research
- Cardiac Ischemia and Reperfusion
- Lung Cancer Research Studies
- Advanced Nanomaterials in Catalysis
- Effects of Radiation Exposure
- Adipose Tissue and Metabolism
Central South University of Forestry and Technology
2021-2024
Central South University
2017-2024
Xiamen University
2017-2024
Guiyang Medical University
2023-2024
Second Xiangya Hospital of Central South University
2017-2024
Ningxia Medical University
2023
First Affiliated Hospital of Xiamen University
2023
Shandong University of Finance and Economics
2021
Zhejiang University
2019-2020
University of South China
2020
Renal ischemia-reperfusion (I/R) injury is the most common cause of AKI, which associates with high mortality and has no effective therapy. ELABELA (ELA) a newly identified 32-residue hormone peptide highly expressed in adult kidney. To investigate whether ELA protective effects on renal I/R injury, we administered mature (ELA32) or 11-residue furin-cleaved fragment (ELA11) to hypoxia-reperfusion (H/R)-injured adriamycin-treated tubular cells vitro ELA32 ELA11 significantly inhibited...
Lung adenocarcinoma (LUAD) is the most common type of lung cancer. Tripartite motif 13 (TRIM13) a member TRIM protein family and downregulated in multiple cancers, especially non-small cell cancers (NSCLC). In this study, we investigated anti-tumor mechanism TRIM13 cancer tissues lines. First, mRNA levels LUAD tissue cells were measured. was overexpressed on to investigate effects proliferation, apoptosis, oxidative stress, p62 ubiquitination, autophagy activation. Finally, mechanistic role...
Glaucoma is the second leading cause of blindness in world. Loss vision glaucomatous optic neuropathy caused by selective degeneration retinal ganglion cells (RGCs). Ocular hypertension a major risk factor glaucoma, but visual field defects continue to progress some patients despite use drugs that lower intraocular pressure. At present, there are no effective neuroprotective strategies for treatment this disease. The extracellular signal-regulated kinase (Erk) 1/2 pathway an evolutionarily...
Liver fibrosis is an outcome of chronic hepatic injury, which can eventually result in cirrhosis, liver failure, and even cancer. The activation stellate cell (HSC) a prominent driver fibrosis. Recently, it has been found that the crosstalk between HSCs immune cells, including macrophages, plays important role initiation development As vital vehicle intercellular communication, exosomes transfer specific cargos into from macrophages. Here, we show derived lipopolysaccharide (LPS)-treated...
This study aimed to elucidate the impact of brain tumors on cerebral edema and glymphatic drainage, leveraging advanced imaging techniques explore relationship between tumor characteristics, function, aquaporin 4 (AQP4) expression.
Background . Bone marrow-derived mesenchymal stem cells (BMSCs) have blossomed into an effective approach with great potential for the treatment of liver fibrosis. The aim this study was to investigate underlying antifibrosis mechanisms by which BMSC inhibit activated hepatic stellate (HSCs) in vivo and vitro. Methods To effect human bone (hBM-MSCs) on HSCs, we used HSCs coculture systems evaluate inhibition from aspects apoptosis HSCs. In addition, activation NADPH oxidase pathway changes...
Fatty liver disease is a growing problem in fish aquaculture and there an urgent need to identify causes possible remedies. In the present study, effects of treating fatty Nile tilapia (Oreochromis niloticus Linnaeus, 1758) with extract derived from herb, Sedum sarmentosum Bunge (SSB), was investigated. We found that SSB could restore changes feed coefficient, immune capacity, pathological index caused by disease, also prevent apoptosis hepatocytes. An RNA-seq analysis showed treatment...
Acquired radio-resistance is thought to be one of the main causes recurrent metastasis after failure nasopharyngeal carcinoma (NPC) radiotherapy, which may related X-ray-induced epithelial–mesenchymal transition (EMT) activation. The circadian clock gene, BMAL1, has been shown correlate with sensitivity NPCs but specific mechanism not reported. NPC cells were irradiated by conventional fractionation generate radiotherapy-resistant cells. BMAL1 gene stabilization/overexpression and...