A5100647183- Radiomics and Machine Learning in Medical Imaging
- Cerebrovascular and Carotid Artery Diseases
- Medical Research and Treatments
- MRI in cancer diagnosis
- Lymphoma Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Acute Myeloid Leukemia Research
- Viral-associated cancers and disorders
- Facial Nerve Paralysis Treatment and Research
- Corneal Surgery and Treatments
- CNS Lymphoma Diagnosis and Treatment
- Metabolomics and Mass Spectrometry Studies
- Lipid metabolism and biosynthesis
- Cancer Immunotherapy and Biomarkers
- Marine Sponges and Natural Products
- Antioxidant Activity and Oxidative Stress
- Acute Ischemic Stroke Management
- Microbial Natural Products and Biosynthesis
- Lymphatic System and Diseases
- Corporate Social Responsibility Reporting
- Head and Neck Cancer Studies
- Effects of Radiation Exposure
- Retinoids in leukemia and cellular processes
- Ear Surgery and Otitis Media
Peking Union Medical College Hospital
2019-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2024
Montefiore Medical Center
2024
Shenzhen University
2024
Ruijin Hospital
2006-2021
Shanghai Jiao Tong University
2009-2021
Shanghai Institute of Hematology
2009-2021
Significance The APL2012 trial is currently the largest randomized, multicenter clinical study of APL based on ATRA-ATO treatment with risk stratification. We enrolled 855 newly diagnosed patients during December 2012 to 2017 for careful follow-up. All received ATRA-ATO–based protocols remission induction. At consolidation phase, key part trial, ATO was used replace or reduce chemotherapy in a risk-stratified way. Patients were then treated as maintenance. results indicated not only...
To examine the prognostic value of a machine learning model trained with pretreatment MRI radiomic features in assessment patients nonmetastatic nasopharyngeal carcinoma (NPC) who are at risk for 3-year disease progression after intensity-modulated radiation therapy and to explain radiomics model. A total 277 NPC admitted between March 2008 December 2014 two imaging centers were retrospectively reviewed. Patients allocated discovery or validation cohort based on where they underwent...
To enhance our comprehension of the fundamental mechanisms driving tumor metabolism and metastasis, it is essential to dynamically monitor intratumoral lipid droplet (LD) collagen processes in vivo. Traditional LD analysis tumors predominantly relies on observations vitro cells or tissue slices, which unfortunately hinder real-time insights into dynamic behavior LDs during vivo progression. In this study, we developed a dual-modality imaging technique that combines coherent anti-Stokes Raman...
Chemical investigation of the marine-derived fungus Aspergillus flavipes 297 led to isolation and identification three drimane-type sesquiterpenoids, asperflavinoid A ( 1) (6-strobilactone-B) esters (E,E)-6,7-dihydroxy-2,4-octadienoic acids (2 3).Asperflavinoid (1) was characterized as unseparated diastereomers its chemical structure determined by spectroscopic analysis NMR MS data.In cytotoxic assay, compound 1 showed promising inhibitory effects on HepG2 MKN-45 cell lines.
ObjectiveTo evaluate the image quality of low-dose temporal bone computed tomography (CT) in otitis media and mastoiditis patients by using deep learning reconstruction (DLR).Materials methodsA total ninety-seven bones from 53 consecutive adult who had suspected underwent CT were prospectively enrolled. All high resolution protocol (group A) an additional B). In group A, data reconstructed filter back projection (FBP). B, DLR mild (B1), standard (B2) strong (B3). The objective was analyzed...
Abstract Background: Early detection of Breast cancer-related lymphedema (BCRL) is crucial since it can significantly reduce the negative impact on a patient’s quality life after breast cancer treatment. Several objective screening methods have been used in prior studies but not proven accurate due to lack standardization. Bioimpedance spectroscopy (BIS), which assesses tissue resistance an electric current and converts into score measure interstitial fluid content, has be tool diagnosing...
To evaluate the image quality of novel dark-blood computed tomography angiography (CTA) imaging combined with deep learning reconstruction (DLR) compared to delayed-phase CTA images hybrid iterative (HIR), visualize cervical artery wall in patients Takayasu arteritis (TAK).
ObjectiveTo investigate the correlation between parameters of PET/MR and expression level epidermal growth factor receptor (EGFR) in head neck squamous cell carcinoma (HNSCC) to evaluate diagnostic efficacy independent combined for EGFR.Materials methods21 patients who had undergone been proven HNSCC pathologically were included this retrospective study. The sequences 18-flurodeoxyglucose (18F-FDG) PET, T1, T2-weighted imaging, DWI, ADC DCE. Parameters including ADCmean from Ktrans, Ve, Kep...
The disclosure of corporate social responsibility reports has attracted more and attention from practitioners researchers. This article exploits Chinese listed firms mandated to disclose CSR as samples, using a DID-PSM approach, it studied whether how non-financial information in have an impact on capital market stock price informativeness. We find that the mandatory decrease informativeness emerging China, we further explore this relation perspectives report quality, intermediate role...
Rituximab is an IgG1 monoclonal antibody approved for the treatment of diffuse large B-cell lymphoma (DLBCL); however, its efficacy poor in some patients. Previous studies indicate that difference may be due to antibody-dependent cell-mediated cytotoxicity (ADCC). The effect ADCC closely related Fc γ receptor IIIA (Fc RIIIa) gene polymorphisms, but no study has investigated this patients with DLBCL China. In study, we explored RIIIa polymorphisms China and ethnic differences gene. Moreover,...