Yu Zhou

ORCID: 0000-0002-3616-3229
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About
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Research Areas
  • Reproductive Biology and Fertility
  • Trypanosoma species research and implications
  • Lysosomal Storage Disorders Research
  • Sperm and Testicular Function
  • Disaster Response and Management
  • Acute Ischemic Stroke Management
  • Pharmacology and Obesity Treatment
  • Safety and Risk Management
  • Technology and Human Factors in Education and Health
  • Pharmaceutical studies and practices
  • Pluripotent Stem Cells Research
  • Injury Epidemiology and Prevention
  • Food Allergy and Anaphylaxis Research
  • 3D Printing in Biomedical Research
  • Mechanical Circulatory Support Devices
  • Law in Society and Culture
  • Tissue Engineering and Regenerative Medicine
  • Sleep and Work-Related Fatigue
  • Hormonal and reproductive studies
  • Genital Health and Disease
  • Pregnancy and preeclampsia studies
  • Cellular transport and secretion
  • Glycogen Storage Diseases and Myoclonus
  • Paraoxonase enzyme and polymorphisms
  • Maternal Mental Health During Pregnancy and Postpartum

Traditional Chinese Medicine Hospital of Kunshan
2024

Shanghai University of Traditional Chinese Medicine
2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2023

University of Chicago
2023

Peking Union Medical College Hospital
2023

Wake Forest University
2022

Forest Institute
2022

Nanjing Medical University
2022

Huaian First People’s Hospital
2022

Sichuan University
2022

Both osteoporosis and tendinopathy are widely prevalent disorders, encountered in diverse medical contexts. Whilst each condition has distinct pathophysiological characteristics, they share several risk factors underlying causes. Notably, oxidative stress emerges as a crucial intersecting factor, playing pivotal role the onset progression of both diseases. This imbalance arises from dysregulation generating neutralising reactive oxygen species (ROS), leading to an abnormal environment....

10.1111/jcmm.18508 article EN cc-by Journal of Cellular and Molecular Medicine 2024-07-01

Background: Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) are promising weight-loss drugs, but real-world data concerning the liability of GLP-1RAs in gastrointestinal safety lacking. We examined differences between semaglutide and liraglutide. Materials Methods: used US Food Drug Administration (FDA) Adverse Event Reporting System (FAERS) database retrieved during first three years liraglutide approved by FDA. Thirteen main adverse drug reactions (GADRs) were evaluated....

10.2147/dmso.s348025 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2022-01-01

Despite its small size, the pituitary gland plays a central role in maintenance of normal homeostasis most physiological systems through regulation function other endocrine glands. The complexity anterior gland, due to composition several different hormone-secreting cell types, begets plethora disorders and pathologies primarily hyposecretion or hypersecretion hormones. gonadotrophs, which make up less than 5% total number cells pituitary, serve regulate gonad development sexual reproduction...

10.1089/scd.2021.0354 article EN Stem Cells and Development 2022-04-06

Background: Mucopolysaccharidosis Type II (MPS II) is a rare, progressive and ultimately fatal X-linked lysosomal storage disorder caused by mutations in the iduronate-2-sulfatase (IDS) gene. This report conducted retrospective analysis to investigate clinical characteristics, genotypes management strategies large cohort of Chinese patients with MPS II. Methods: In this study, we explored 130 between September 2008 April 2022. Clinical manifestations, auxiliary examination, IDS pathogenic...

10.3389/fgene.2023.1103620 article EN cc-by Frontiers in Genetics 2023-01-13

Hydroxyurea (HU), a small molecule with various biological properties, was used in myeloproliferative, tumorous, and non-hematological diseases. However, whether HU plays role diabetic cardiomyopathy (DCM) remains unclear. Our study aimed to investigated could ameliorate DCM or not. Induction of type 1 diabetes mellitus (T1DM) C57BL/6 J mice achieved by intraperitoneal injection streptozotocin (STZ). Mice control groups were treated (20 mg/kg) drinking water for 16 weeks. data showed that...

10.1016/j.biopha.2022.113291 article EN Biomedicine & Pharmacotherapy 2022-06-16

Objective Reproductive hormones are a traditional good method to evaluate spermatogenesis but might not accurately represent local spermatogenesis. To find more accurate method, seminal reproductive were studied. Methods A bidirectional cohort study was performed. total of 126 infertile men from 2018 2019 retrospectively analyzed. They divided into nonobstructive azoospermia (NOA), oligozoospermia (OLZ) and normal (NOR) groups. prospective conducted on patients in the NOA OLZ groups for 2...

10.3389/fendo.2022.992556 article EN cc-by Frontiers in Endocrinology 2022-12-08

This retrospective study aimed to explore the effects of goal-oriented nursing intervention (GONI) on postpartum depression (PPD). We retrospectively analyzed medical records 72 women with PPD. They were allocated a treatment group (n = 36, exercise plus GONI) or control exercise). Patients in both groups received total 3 months treatment. Outcomes included 17-item Hamilton Rating Scale for Depression (HAMD-17) score, HAMD-17 response rate (≥50% score reduction), remission (score ≤ 7), and...

10.1097/md.0000000000030651 article EN cc-by-nc Medicine 2022-09-16

Pulsed field ablation (PFA), an emerging treatment method for atrial fibrillation, has demonstrated significant potential in arrhythmia therapy. PFA employs high-intensity, short-duration electric fields to induce irreversible electroporation myocardial cells, disrupting abnormal cardiac rhythms, and restoring normal heart function. This technique exhibits high success rates low recurrence animal studies early clinical trials, offering advantages over traditional methods by reducing damage...

10.61189/758818obsmms article EN Progress in Medical Devices 2024-06-30

Recurrent aphthous ulcer (RAU) is one of the most common diseases oral mucosa, which generally believed to be related immunity, though etiology still unclear. It suspected that allergies are directly RAU. So we sought explore relationship between hypersensitivity and RAU.40 RAU patients who were in ulceration period 40 people good health selected from Jan 2016 Feb 2017, matched age sex. The peripheral blood antigens healthy was tested, serum specific IgE (sIgE) with 6 groups total (tIgE)...

10.1016/j.jds.2022.05.014 article EN cc-by-nc-nd Journal of Dental Sciences 2022-06-04

Mucopolysaccharidosis type IIIA (MPS IIIA) is a lysosomal storage disorder caused by N-sulfoglucosamine sulfohydrolase (SGSH) deficiency. SGSH removes the sulfate from residues on nonreducing end of heparan (HS-NRE) within lysosomes. Enzyme deficiency results in accumulation partially degraded HS lysosomes throughout body, leading to progressive severe neurological disease. replacement therapy has been proposed, but further evaluation treatment strategy needed. Here, we used Chinese hamster...

10.1016/j.jbc.2022.102625 article EN cc-by-nc-nd Journal of Biological Chemistry 2022-10-26

Objective To investigate the condition of flight fatigue and its relationship with mental health in pilots base transformation on purpose providing reference for comprehensive intervention during transformation. Methods Both 90 transformed non-transformed were tested by assessment instrument (FAI) symptom checklist (SCL-90). Thirty-eight 38 selected to continuously record ECG 1 h analysis heart rate variability (HRV). Correlation was done health. Results ①FAI score results:...

10.3760/cma.j.issn.1007-6239.2016.02.003 article EN Chinese Journal of Aerospace Medicine 2016-06-15
Thomas Neill Liliana Schaefer Renato V. Iozzo John L. Wallace Allison A. Madigan and 95 more Kevin J. Rycyna Anil V. Parwani Yeipyeng J. Datiri Ahmed Basudan Kathryn M. Sobek Jessica Cummings H Basse Dean J. Bacich Denise O'keefe Matias Knuuttila Emrah Yatkin Jenny Kallio Saija Savolainen Teemu D. Laajala Tero Aittokallio Riikka Oksala Merja R. Häkkinen Pekka Keski‐Rahkonen Seppo Auriola Matti Poutanen Sari Mäkelä Delphine Chrisment Pierre Dubus Lucie Chambonnier Anaïs Hocès de la Guardia Elodie Sifré Alban Giese Myriam Capone Camille Khairallah Pierre Costet Benoı̂t Rousseau Christophe Hubert Odile Burlen‐Defranoux Christine Varon António Bandeira Françis Mégraud Philippe Lehours Franziska Schulze Tina Beckmann Falk Nimmerjahn Akira Ishiko Mattias Collin Jörg Köhl Stephanie Goletz Detlef Zillikens Ralf Ludwig Enno Schmidt Nicolas Guyot Julien Wartelle Laurette Malleret Alexandre A. Todorov Gilles Devouassoux Yves Pachéco Dieter E. Jenne Azzaq Belaaouaj Takanori Kumagai Cindy Baldwin Lamine Aoudjit Lisa Nezvitsky Richard Robins Ruihua Jiang Tomoko Takano Yu Zhou Daniel J. Lovell Maigen Bethea Zhan Wang George J. Christ Shay Söker Tracy Criswell Jayakumar Thangavel Asrar B. Malik Harold K. Elias Sheeja Rajasingh Andrew Simpson Premanand Sundivakkam Stephen B. Vogel Yu‐Ting Xuan Buddhadeb Dawn Johnson Rajasingh Tomoki Yagai Atsushi Miyajima Minoru Tanaka WU Li-ling Wei‐Hao Peng Wei‐Ting Kuo Ching‐Ying Huang Yen–Hsuan Ni Kuo‐Shyan Lu Jerrold R. Turner Linda Chia‐Hui Yu Wenjuan Duan Xueqing Yu Xiao‐Ru Huang Jianwen Yu Hui Yao

10.1016/s0002-9440(14)00331-9 article EN publisher-specific-oa American Journal Of Pathology 2014-07-18
Mark E. Sobel Makhosazane Zungu Jonathan C. Schisler M. Faadiel Essop Christopher R. McCudden and 95 more Cam Patterson Monte S. Willis Andrei Turtoï Edwin De Pauw Vincent Castronovo Samielle Brancato Jorge E. Albina Ettore Capoluongo Thomas K. Morrison Lauren Oko Stephanie A. Montgomery Alan C. Whitmore Alina R. Lotstein Bronwyn M. Gunn Susan Elmore Mark T. Heise Xu Wang Ye Li Yu Zhou Miao Liu Ding Zhou W Ho Pablo M. Peixoto Jennifer Kimberly Lue Shin‐Young Ryu Brian Wroble Jill C. Sible Kathleen W. Kinnally Barend Mees Alice Re ́calde Céline Loinard Dennie Tempel Marcia Godinho Jose ́vilar Rien Van Haperen Bernard Le ́vy Rini de Crom J. B. Silvestre Michael F. Greene Flora Sam Pamela Hoo Rupesh S. Patel David W. Seldin Lawreen H. Connors Gerold Bepler Ken Andre A.L. Vataire Jean Charles Soria Zhong Zheng Ariane Dunant Jean‐Pierre Pignon Michael J. Schell Pierre Fouret Robert Pirker Martin Filipits Élisabeth Brambilla Gustavo Ayala Bahar Muezzinoglu Kai Hammerich Anna Frolov Hao Liu Peter T. Scardino Rile Li Mohammad Sayeeduddin Michael Ittmann Dov Kadmon Brian J. Miles Thomas M. Wheeler David R. Rowley Amalia Conti Gemma Caballero Rodriguez Antonella Chiechi Rosa De ́gano Blazquez Victoria Barbado Tibor Kre Nacs Chiara Novello Laura Pazzaglia Irene Quattrini Licciana Zanella Piero Picci Enrique De Alava Maria Serena Benassi Kristin Shields Evgeniy Panzhinskiy Nana Burns W. Michael Zawada Moumita Das Ning Shen Tao Gong Jiandong Wang Fanli Meng Long Qiao Run-Lin Yang Bin Xue

On the Cover:Apoptotic bystander effects can be induced in vivo by mimicking formation of mitochondrial apoptosis-induced channel (MAC).Single-cell microinjection cytochrome c Xenopus embryos initiates waves apoptosis (loss pigmentation, as seen at top image) from injected cells to neighboring cells.Thus, a death signal generated downstream release diffused and ultimately killed cells.(See page 48.

10.1016/s0002-9440(10)00144-6 article EN cc-by-nc-nd American Journal Of Pathology 2011-01-01

Hypertension is a leading risk factor for cardiovascular disease, which especially prevalent among minority urban patients. Our group and others have previously shown that socio-environmental factors such as crime poverty raise risk. However, the acute effects of local gunfire on patients’ blood pressure are unknown. We hypothesized in our South Side Chicago community was temporally associated with an rise nearby performed retrospective cohort study including 7,564 patients aged 18-104 who...

10.1161/circ.148.suppl_1.17255 article EN Circulation 2023-11-07

Background: It is well recognized that labiaplasty the most common procedure of female cosmetic genital surgeries. The literature examining postoperative satisfaction not yet robust and there lack long-term follow up. might be necessary to conduct statistics these techniques so outcomes can better discussed preoperatively. Herein, we develop a stand-alone system serve as preoperative assessment resource based on follow-up 414 patients with reduction labiaplasty.Objectives: aim study was...

10.2139/ssrn.4052335 article EN SSRN Electronic Journal 2022-01-01
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