- Reproductive Biology and Fertility
- Trypanosoma species research and implications
- Lysosomal Storage Disorders Research
- Sperm and Testicular Function
- Disaster Response and Management
- Acute Ischemic Stroke Management
- Pharmacology and Obesity Treatment
- Safety and Risk Management
- Technology and Human Factors in Education and Health
- Pharmaceutical studies and practices
- Pluripotent Stem Cells Research
- Injury Epidemiology and Prevention
- Food Allergy and Anaphylaxis Research
- 3D Printing in Biomedical Research
- Mechanical Circulatory Support Devices
- Law in Society and Culture
- Tissue Engineering and Regenerative Medicine
- Sleep and Work-Related Fatigue
- Hormonal and reproductive studies
- Genital Health and Disease
- Pregnancy and preeclampsia studies
- Cellular transport and secretion
- Glycogen Storage Diseases and Myoclonus
- Paraoxonase enzyme and polymorphisms
- Maternal Mental Health During Pregnancy and Postpartum
Traditional Chinese Medicine Hospital of Kunshan
2024
Shanghai University of Traditional Chinese Medicine
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2023
University of Chicago
2023
Peking Union Medical College Hospital
2023
Wake Forest University
2022
Forest Institute
2022
Nanjing Medical University
2022
Huaian First People’s Hospital
2022
Sichuan University
2022
Both osteoporosis and tendinopathy are widely prevalent disorders, encountered in diverse medical contexts. Whilst each condition has distinct pathophysiological characteristics, they share several risk factors underlying causes. Notably, oxidative stress emerges as a crucial intersecting factor, playing pivotal role the onset progression of both diseases. This imbalance arises from dysregulation generating neutralising reactive oxygen species (ROS), leading to an abnormal environment....
Background: Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) are promising weight-loss drugs, but real-world data concerning the liability of GLP-1RAs in gastrointestinal safety lacking. We examined differences between semaglutide and liraglutide. Materials Methods: used US Food Drug Administration (FDA) Adverse Event Reporting System (FAERS) database retrieved during first three years liraglutide approved by FDA. Thirteen main adverse drug reactions (GADRs) were evaluated....
Despite its small size, the pituitary gland plays a central role in maintenance of normal homeostasis most physiological systems through regulation function other endocrine glands. The complexity anterior gland, due to composition several different hormone-secreting cell types, begets plethora disorders and pathologies primarily hyposecretion or hypersecretion hormones. gonadotrophs, which make up less than 5% total number cells pituitary, serve regulate gonad development sexual reproduction...
Background: Mucopolysaccharidosis Type II (MPS II) is a rare, progressive and ultimately fatal X-linked lysosomal storage disorder caused by mutations in the iduronate-2-sulfatase (IDS) gene. This report conducted retrospective analysis to investigate clinical characteristics, genotypes management strategies large cohort of Chinese patients with MPS II. Methods: In this study, we explored 130 between September 2008 April 2022. Clinical manifestations, auxiliary examination, IDS pathogenic...
Hydroxyurea (HU), a small molecule with various biological properties, was used in myeloproliferative, tumorous, and non-hematological diseases. However, whether HU plays role diabetic cardiomyopathy (DCM) remains unclear. Our study aimed to investigated could ameliorate DCM or not. Induction of type 1 diabetes mellitus (T1DM) C57BL/6 J mice achieved by intraperitoneal injection streptozotocin (STZ). Mice control groups were treated (20 mg/kg) drinking water for 16 weeks. data showed that...
Objective Reproductive hormones are a traditional good method to evaluate spermatogenesis but might not accurately represent local spermatogenesis. To find more accurate method, seminal reproductive were studied. Methods A bidirectional cohort study was performed. total of 126 infertile men from 2018 2019 retrospectively analyzed. They divided into nonobstructive azoospermia (NOA), oligozoospermia (OLZ) and normal (NOR) groups. prospective conducted on patients in the NOA OLZ groups for 2...
This retrospective study aimed to explore the effects of goal-oriented nursing intervention (GONI) on postpartum depression (PPD). We retrospectively analyzed medical records 72 women with PPD. They were allocated a treatment group (n = 36, exercise plus GONI) or control exercise). Patients in both groups received total 3 months treatment. Outcomes included 17-item Hamilton Rating Scale for Depression (HAMD-17) score, HAMD-17 response rate (≥50% score reduction), remission (score ≤ 7), and...
Pulsed field ablation (PFA), an emerging treatment method for atrial fibrillation, has demonstrated significant potential in arrhythmia therapy. PFA employs high-intensity, short-duration electric fields to induce irreversible electroporation myocardial cells, disrupting abnormal cardiac rhythms, and restoring normal heart function. This technique exhibits high success rates low recurrence animal studies early clinical trials, offering advantages over traditional methods by reducing damage...
Recurrent aphthous ulcer (RAU) is one of the most common diseases oral mucosa, which generally believed to be related immunity, though etiology still unclear. It suspected that allergies are directly RAU. So we sought explore relationship between hypersensitivity and RAU.40 RAU patients who were in ulceration period 40 people good health selected from Jan 2016 Feb 2017, matched age sex. The peripheral blood antigens healthy was tested, serum specific IgE (sIgE) with 6 groups total (tIgE)...
Mucopolysaccharidosis type IIIA (MPS IIIA) is a lysosomal storage disorder caused by N-sulfoglucosamine sulfohydrolase (SGSH) deficiency. SGSH removes the sulfate from residues on nonreducing end of heparan (HS-NRE) within lysosomes. Enzyme deficiency results in accumulation partially degraded HS lysosomes throughout body, leading to progressive severe neurological disease. replacement therapy has been proposed, but further evaluation treatment strategy needed. Here, we used Chinese hamster...
Objective To investigate the condition of flight fatigue and its relationship with mental health in pilots base transformation on purpose providing reference for comprehensive intervention during transformation. Methods Both 90 transformed non-transformed were tested by assessment instrument (FAI) symptom checklist (SCL-90). Thirty-eight 38 selected to continuously record ECG 1 h analysis heart rate variability (HRV). Correlation was done health. Results ①FAI score results:...
On the Cover:Apoptotic bystander effects can be induced in vivo by mimicking formation of mitochondrial apoptosis-induced channel (MAC).Single-cell microinjection cytochrome c Xenopus embryos initiates waves apoptosis (loss pigmentation, as seen at top image) from injected cells to neighboring cells.Thus, a death signal generated downstream release diffused and ultimately killed cells.(See page 48.
Hypertension is a leading risk factor for cardiovascular disease, which especially prevalent among minority urban patients. Our group and others have previously shown that socio-environmental factors such as crime poverty raise risk. However, the acute effects of local gunfire on patients’ blood pressure are unknown. We hypothesized in our South Side Chicago community was temporally associated with an rise nearby performed retrospective cohort study including 7,564 patients aged 18-104 who...
Background: It is well recognized that labiaplasty the most common procedure of female cosmetic genital surgeries. The literature examining postoperative satisfaction not yet robust and there lack long-term follow up. might be necessary to conduct statistics these techniques so outcomes can better discussed preoperatively. Herein, we develop a stand-alone system serve as preoperative assessment resource based on follow-up 414 patients with reduction labiaplasty.Objectives: aim study was...