A5015897162- Turtle Biology and Conservation
- Sperm and Testicular Function
- Acute Myeloid Leukemia Research
- Physiological and biochemical adaptations
- Reproductive biology and impacts on aquatic species
- Extracellular vesicles in disease
- Zebrafish Biomedical Research Applications
- MicroRNA in disease regulation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Heavy metals in environment
- Autophagy in Disease and Therapy
- Heavy Metals in Plants
- Retinoids in leukemia and cellular processes
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Animal Nutrition and Physiology
- Heavy Metal Exposure and Toxicity
- Animal Diversity and Health Studies
- Animal Virus Infections Studies
- Neuropeptides and Animal Physiology
- Animal Behavior and Reproduction
- Cancer-related molecular mechanisms research
- Lipid metabolism and biosynthesis
- Aquaculture disease management and microbiota
- Erythrocyte Function and Pathophysiology
Ruijin Hospital
2011-2025
Shanghai Jiao Tong University
2015-2025
Shanghai Institute of Hematology
2015-2025
Nanjing Agricultural University
2015-2024
Tianjin Academy of Agricultural Sciences
2016-2024
Zhengzhou Central Hospital
2015-2024
Nanchang University
2016-2024
Guangdong Medical College
2008-2023
Nanjing University of Science and Technology
2020-2023
Institute of Quality Standards and Testing Technology for Agro Products
2021
Winter jujube (Ziziphus jujuba Mill. cv. Dongzao) is a late-maturing and superior fresh variety. However, there have been few reports on the comprehensive evaluation of winter quality. Here, we revealed differences characteristics 46 sensory nutritional quality indices from four main producing areas in China. Moreover, Pearson correlation analysis, principal component hierarchical clustering analysis were employed to comprehensively evaluate jujube. As result, 89.13 % tested significantly...
Pneumonia is the leading cause of death among children under five, and kill almost two million each year. Quercetin, a flavonoid polyphenolic compound, exerts many beneficial biological activities, including anti-inflammatory functions. Our study aimed to investigate possibility quercetin as therapeutic agent for pneumonia its role in inflammatory response induced by lipopolysaccharide (LPS).
Apoptosis is a tightly controlled process by which tissues eliminate unwanted cells. Spontaneous germ cell apoptosis in testis has been broadly investigated mammals that have an associated spermatogenesis pattern. However, the mechanism of seasonally breeding reptiles following dissociated remained enigmatic. In present study, morphological evidence clearly confirmed pattern Pelodiscus sinensis. TUNEL and TEM analyses presented dynamic changes ultrastructural characteristics apoptotic cells...
Osteoporosis (OP) is considered as one of the major comorbidities rheumatoid arthritis (RA), and responsible for fragility fracture. However, there currently no effective treatment RA complicated with OP. Tubson-2 decoction (TBD), a Mongolian medicine also known Erwei Duzhong Decoction, has been shown to exert preventive effect on post-menopausal osteoporosis (PMOP). The effects TBD RA-induced OP, well bioactive compound underlying mechanisms, remain be elucidated.To explore OP in vivo,...
Acute myeloid leukemia (AML) treatment relied on anthracyclines and cytarabine based intensive chemotherapy. However, clinical outcomes are unsatisfied for patients with intermediate/adverse cytogenetics European Leukemia Net (ELN) risk stratification 2022 (ELN 2022), relapses also remain common even in favorable-risk measurable residual disease (MRD). There is an urgent unmet need optimizing chemotherapy regimens novel agents, to enhance the MRD-negative rate, achieve durable remission,...
Abstract Telocytes (Tcs) are cells with telopodes (Tps), which very long cellular extensions alternating thin segments (podomers) and dilated bead‐like thick regions known as podoms. Tcs a distinct category of interstitial have been identified in many mammalian organs including heart, lung kidney. The present study investigates the existence, ultrastructure, distribution contacts surrounding uterus (shell gland) oviduct C hinese soft‐shelled turtle, P elodiscus sinensis . Samples from...
In this study, we investigated the localization, morphological features and cellular interactions of telocytes in rat testicular interstitium. Transmission electron microscopy (TEM) immunohistochemical immunofluorescence analyses interstitium showed a distinct layer surround seminiferous tubules along with inner peritubular myoid cells. The majority were made up small cell body moniliform prolongations that contained mitochondria secretory vesicles. Some other observed possessing large...
Abstract The fine structures, enzyme histochemical, and immunohistochemical characterization of liver in zebrafish were investigated using light microscopy electron microscopy. results showed that was separated into three lobes each lobe had a central vessel comparable to the mammalian vein. However typical hepatic lobules, portal areas, arteries not observed. A vein entered its tributaries connected directly sinusoids, which then converged vessel. Three vessels finally carried blood out...
Uterine inflammation occurs after calving in association with extensive endometrial remodelling and bacterial contamination. If the persists, it leads to reduced fertility. Chronic endometritis is highly prevalent high-yielding cows that experience negative energy balance (NEB) early lactation. This study investigated effect of NEB on antimicrobial peptides S100A8 S100A9 involuting uteri collected 2 weeks post partum . Holstein-Friesian (six per treatment) were randomly allocated two...
Abstract Telocytes ( TC s) are novel interstitial cells that have been found in various organs, but the existence of s testes has not yet reported. The present ultrastructural and immunohistochemical study revealed differentiate these from peritubular (Pc) contact with surrounding structures testes. Firstly, our results confirmed two cell types seminiferous tubules; were Pc (smooth muscle like characteristics) (as an outer layer around Pc). their long thin prolongations called telopodes...
Abstract Based on the leukemia‐associated immunophenotypes (LAIPs), minimal residual disease (MRD) related to outcome can be detected by multiparameter flow cytometry in acute myeloid leukemia (AML) patients. Although 0.1% was commonly used as a cutoff value, measurable MRD or level below has also been associated with prognostic significance and more sensitive thresholds (<0.1%) are required for improving AML prognosis prediction. In this study, 292 adult patients diagnosed (non‐M3) were...
Winter jujube (Ziziphus jujuba 'Dongzao') is greatly appreciated by consumers for its excellent quality, but brand infringement frequently occurs in the market. Here, we first determined a total of 38 elements 167 winter samples from main producing areas China inductively coupled plasma mass spectrometer (ICP-MS). As result, 16 (Mg, K, Mn, Cu, Zn, Mo, Ba, Be, As, Se, Cd, Sb, Ce, Er, Tl and Pb) exhibited significant differences different areas. Supervised linear discriminant analysis (LDA)...
Abstract Spermiogenesis in the soft‐shelled turtle, Pelodiscus sinensis , was examined by transmission electron microscopy. The process includes nuclear elongation, chromatin condensation, acrosomal and flagellar development, elimination of excess cytoplasm. In stage I, proacrosomal vesicle occurs next to a shallow fossa nucleus, dense granule forms beneath it. A smaller subacrosomal middle fibrous layer is related development intranuclear tubules. nucleus begins move eccentrically. II,...
D1-cytoplasmic male sterility (CMS) rice is a sporophytic cytoplasmic male-sterile developed from Dongxiang wild that exhibits no-pollen-grain phenotype. A mitochondrial chimeric gene (orf182) was detected by genome sequencing and comparative analysis. Orf182 composed of three recombinant fragments, the largest which homologous to Sorghum bicolor sequences. In addition, orf182 found only in species collected China. Northern blot analysis showed transcripts were affected Rf genes...
To assess levels of contamination and human health risk, we analyzed the concentrations heavy metals lead (Pb), cadmium (Cd), chromium (Cr), nickel (Ni) in China's main deciduous fruits — apple, pear, peach, grape, jujube. The concentration order was Ni>Cr>Pb>Cd. In 97.5% samples, metal were within maximum permissible limits. Among studied, jujube peach proved to be highest, those grape lowest. Only 2.2% samples polluted by Ni, only 0.4% Pb, no Cd or Cr. Compared with other fruits, combined...
Sperm storage in vivo extends the time window for fertilisation several animal species, from a few days to years. The underlying mechanisms, however, are largely unknown. In this study, spermatozoa epididymis and oviduct of Chinese soft-shelled turtles were investigated identify potentially relevant morphological features transformations at different stages sperm storage. Large cytoplasmic droplets (CDs) containing lipid (LDs) attached midpiece most epididymis, without migrating down tail....
Sertoli cells (SCs) play a central role in the development of germ within functional testes and exhibit varying morphology during spermatogenesis. This present study investigated seasonal morphological changes SCs reproductive cycle Pelodiscus sinensis by light microscopy, transmission electron microscopy (TEM), immunohistochemistry. During hibernation period with quiescent spermatogenesis, several autophagosomes were observed inside SCs, processes which retracted. In early when started to...