A5101605961- Airway Management and Intubation Techniques
- Anesthesia and Sedative Agents
- Respiratory Support and Mechanisms
- Anesthesia and Pain Management
- Anesthesia and Neurotoxicity Research
- Tracheal and airway disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Intensive Care Unit Cognitive Disorders
- Obstructive Sleep Apnea Research
- Enhanced Recovery After Surgery
- Cancer, Stress, Anesthesia, and Immune Response
- Myasthenia Gravis and Thymoma
- Infection Control and Ventilation
- Nausea and vomiting management
- Head and Neck Surgical Oncology
- Pituitary Gland Disorders and Treatments
- Optical Imaging and Spectroscopy Techniques
- Thermal Regulation in Medicine
- Hemodynamic Monitoring and Therapy
- Craniofacial Disorders and Treatments
- Plant-based Medicinal Research
- Healthcare professionals’ stress and burnout
- Abdominal Surgery and Complications
- Pneumothorax, Barotrauma, Emphysema
- Protein Tyrosine Phosphatases
Chinese Academy of Medical Sciences & Peking Union Medical College
2009-2024
Beijing Hospital
2012-2024
Tianjin University
2024
Academia Sinica
2020-2021
Peking University First Hospital
2021
Peking University
2021
Beijing Shijitan Hospital
2021
Capital Medical University
2021
Peking University Third Hospital
2021
Cleveland Clinic
2021
Tracheal intubation in coronavirus disease 2019 (COVID-19) patients creates a risk to physiologically compromised and attending healthcare providers. Clinical information on airway management expert recommendations these are urgently needed. By analysing two-centre retrospective observational case series from Wuhan, China, panel of international experts discussed the results formulated consensus for tracheal COVID-19 patients. Of 202 undergoing emergency intubation, most were males (n=136;...
Coronavirus Disease 2019 (COVID-19), caused by a novel coronavirus (SARS-CoV-2), is highly contagious disease. It firstly appeared in Wuhan, Hubei province of China December 2019. During the next two months, it moved rapidly throughout and spread to multiple countries through infected persons travelling air. Most patients have mild symptoms including fever, fatigue cough. But severe cases, can progress develop acute respiratory distress syndrome, septic shock, metabolic acidosis...
Abstract The outbreak of the new Coronavirus disease, COVID-19, has been involved in 77,262 cases China as well 27 other countries February 24, 2020. Because virus is novel to human beings, and there no vaccine yet available, every individual susceptible can become infected. Healthcare workers are at high risk, unfortunately, more than 3,000 healthcare have Anesthesiologists among who an even higher risk becoming infected because their close contact with patients potential exposure...
Background Delirium is a common and serious postoperative complication, especially in the elderly. Epidural anesthesia may reduce delirium by improving analgesia, reducing opioid consumption, blunting stress response to surgery. This trial therefore tested hypothesis that combined epidural–general reduces incidence of elderly patients recovering from major noncardiac Methods Patients aged 60 90 yr scheduled for thoracic or abdominal surgeries expected last 2 h more were enrolled....
Background/Objective Inadvertent intraoperative hypothermia (core temperature <360 C) is a recognized risk in surgery and has adverse consequences. However, no data about this complication China are available. Our study aimed to determine the incidence of inadvertent its associated factors sample Chinese patients. Methods We conducted regional cross-sectional survey Beijing from August through December, 2013. Eight hundred thirty patients who underwent various operations under general...
The Chinese health care system must meet the needs of 19% world's population. Despite recent economic growth, resources are unevenly distributed. This creates potential for job stress and burnout. We therefore conducted a survey among anesthesiologists in Beijing-Tianjin-Hebei region focusing on satisfaction burnout to determine incidence associated factors.A large cross-sectional study was performed China. anonymous questionnaire designed collect analyze following information: (1)...
Experimental and observational research suggests that combined epidural-general anesthesia may improve long-term survival after cancer surgery by reducing anesthetic opioid consumption blunting surgery-related inflammation. This study therefore tested the primary hypothesis improves in elderly patients.
Abstract Transnasal humidified rapid insufflation ventilator exchange (THRIVE) may be effective in delaying hypoxia, but the efficacy of THRIVE for oxygenation elderly patients under general anaesthesia has not been assessed. This study assessed whether prolonged apnoea time after induction. was a single centre, two-group, randomized controlled trial. 60 (65 to 80 years age) with American Society Anesthesiologists (ASA) grades I ~ III who required tracheal intubation or application laryngeal...
To preliminary evaluate the application of SaCoVLM™ video laryngeal mask airway in management general anesthesia.We recruited 100 adult patients (ages 18-78 years, male 19, female 81, weight 48-90 kg) with normal predicted (Mallampati I ~ II, unrestricted mouth opening, head and neck mobility) ASA I-II who required anaesthesia. The was inserted after anesthesia induction connected machine for ventilation. Our primary outcome glottic visualization grades. Secondary outcomes included seal...
In Brief BACKGROUND: this study, we evaluated the predicted blood and effect-site C50 for propofol remifentanil target-controlled infusion Bispectral Index (BIS) values at loss of consciousness (LOC) response to a standard noxious painful stimulus in Chinese patients. We hypothesized that these would be different from previously published data on Caucasians. METHODS: Five medical centers enrolled 405 ASA physical status I II unpremedicated patients (97 men, 308 women) aged 18–65 yr. Propofol...
Abstract Background When a difficult airway is unanticipatedly encountered and the initial laryngoscopic intubation fails, supraglottic device (SAD) may be placed to aid ventilation oxygenation, act as conduit for intubation. SaCoVLM™, new SAD, can offer direct vision guide However, no study has evaluated performance of SaCoVLM™ video laryngeal mask (VLM) i-gel combined with flexible bronchoscopy (FB)-guided in management during general anesthesia. Methods A total 120 adult patients were...
Dwarfism is characterized by short stature. Pregnancy in women with dwarfism uncommon and cesarean section generally indicated for delivery. Patients are high-risk population both general regional anesthesia, let alone an emergency surgery.In this case report we present a 27-year-old Chinese puerpera who underwent under combined spinal epidural anesthesia.It original report, which provides instructive significance anesthesia management especially rare condition. There was only one former...
Myocardial ischemia/reperfusion injury is a common clinical problem and can result in severe cardiac dysfunction. Previous studies have demonstrated the protection of electroacupuncture against myocardial injury. However, role X-box binding protein I (XBP1) signaling pathway was still elusive. Thus, we designed this study that significantly improved function during reduced infarct size. Electroacupuncture treatment further inhibited manifested by decrease activities serum lactate...
Background: In this prospective randomized study, we compared the predicted blood and effect-site C50 for propofol remifentanil target-controlled infusion (TCI) bispectral index (BIS) values at loss of consciousness (LOC) response to a standard noxious painful stimulus (LOS) in elderly young patients, respectively. We hypothesized that patients will require lower target concentration both above two clinical end-points. Methods: There were 80 American Society Anesthesiologists (ASA) physical...
Delirium is a common complication in elderly patients after surgery and associated with increased morbidity mortality. Studies suggest that deep anesthesia intense pain are important precipitating factors of postoperative delirium. Neuraxial block frequently used combination general for undergoing major thoracic abdominal surgery. Compared alone intravenous analgesia, combined epidural-general epidural analgesia decreases the requirement anesthetics during provided better relief However,...
septic shock were based on the principles of defi nition and diagnosis proposed by International Sepsis Definitions Conference (class I).
The microsomal CYP2C9 alleles involved in the biotransformation of propofol, a widely used anesthetic agent, were investigated vitro. To examine enzymatic activity alleles, kinetic parameters for propofol 4-hydroxylation determined recombinant human P450s microsomes from Sf21 insects cells carrying CYP2C9*1 and other variants. Some variants showed decreased enzyme compared with wild type, as previously reported. Two (CYP2C9*36 *56) found substantially to increase intrinsic clearance relative...
Bispectral index (BIS) is considered very useful to guide anesthesia care in elderly patients, but its use controversial for the evaluation of adequacy analgesia. This study compared BIS changes response loss consciousness (LOC) and somatic (LOS) nociceptive stimuli between young patients receiving intravenous target-controlled infusion (TCI) propofol remifentanil.This was performed on 52 (aged 65-78 years) 25-58 years), American Society Anesthesiologists physical status I or II. Anesthesia...