I. Nakamura

ORCID: 0000-0002-7640-5456
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About
Contact & Profiles
Research Areas
  • Particle physics theoretical and experimental studies
  • Quantum Chromodynamics and Particle Interactions
  • High-Energy Particle Collisions Research
  • Neutrino Physics Research
  • Dark Matter and Cosmic Phenomena
  • Particle Detector Development and Performance
  • Computational Physics and Python Applications
  • Astrophysics and Cosmic Phenomena
  • Particle Accelerators and Free-Electron Lasers
  • Medical Imaging Techniques and Applications
  • Black Holes and Theoretical Physics
  • Nuclear physics research studies
  • Muon and positron interactions and applications
  • Superconducting Materials and Applications
  • Atomic and Subatomic Physics Research
  • Crystallization and Solubility Studies
  • Radiation Detection and Scintillator Technologies
  • Cosmology and Gravitation Theories
  • X-ray Diffraction in Crystallography
  • Bone Metabolism and Diseases
  • Bone health and treatments
  • Particle accelerators and beam dynamics
  • Immune Cell Function and Interaction
  • Nuclear Physics and Applications
  • Drug-Induced Ocular Toxicity

High Energy Accelerator Research Organization
2013-2022

The Graduate University for Advanced Studies, SOKENDAI
2018-2021

Astellas Pharma (China)
2021

Hokkaido University
2010-2014

The University of Tokyo
2002-2013

Philadelphia University
2003-2013

University of Pennsylvania
2003-2013

Meisei University
2013

Kobe University
2001-2012

Campbell Collaboration
2012

Osteoclast activation is initiated by adhesion to the bone surface, followed cytoskeletal rearrangement, formation of sealing zone, and a polarized ruffled membrane. This study shows that PYK2/CAKbeta/RAFTK, cytoplasmic kinase related focal kinase, highly expressed in rat osteoclasts vivo. Using murine osteoclast-like cells (OCLs) or their mononuclear precursors (pOCs), generated coculture marrow osteoblastic MB1.8 cells, we show: (a) tyrosine phosphorylation PYK2 upon ligation beta3...

10.1172/jci3212 article EN Journal of Clinical Investigation 1998-09-01

The Collins effect connects transverse quark spin with a measurable azimuthal dependence in the yield of hadronic fragments around quark's momentum vector. Using two different reconstruction methods, we find evidence statistically significant asymmetries for charged pion pairs e(+)e(-) annihilation at center-of-mass energy 10.52 GeV, which can be attributed to polarization primordial quarks. measurement was performed using sample 79 x 10(6) events collected Belle detector.

10.1103/physrevlett.96.232002 article EN Physical Review Letters 2006-06-14

10.1016/s0076-6879(97)82110-6 article EN Methods in enzymology on CD-ROM/Methods in enzymology 1997-01-01

We have established a method for obtaining an enriched preparation of functionally active osteoclast-like multinucleated cells (enriched OCLs) from co-cultures mouse primary osteoblasts and bone marrow cells. Using these OCLs, the effect osteoblastic on osteoclast function was examined in two assays: pit formation assay actin ring formation. The OCLs cultured 24 h dentine slices formed only few resorption pits. When various numbers were added to areas pits increased proportionally number...

10.1210/endo.137.8.8754795 article EN Endocrinology 1996-08-01

We have established a method for obtaining an enriched preparation of functionally active osteoclast-like multinucleated cells (enriched OCLs) from co-cultures mouse primary osteoblasts and bone marrow cells. Using these OCLs, the effect osteoblastic on osteoclast function was examined in two assays: pit formation assay actin ring formation. The OCLs cultured 24 h dentine slices formed only few resorption pits. When various numbers were added to areas pits increased proportionally number...

10.1210/endo.137.5.8612568 article EN Endocrinology 1996-05-01

We report an observation of the decay $B^0\to D^{*-} \tau^+ \nu_{\tau}$ in a data sample containing $535\times10^6$ $B\bar{B}$ pairs collected with Belle detector at KEKB asymmetric-energy $e^+e^-$ collider. find signal significance 5.2 standard deviations and measure branching fraction $\mathcal{B}(B^0\to \tau ^+ \nu_{\tau})=(2.02 ^{+0.40}_{-0.37} (stat) \pm 0.37 (syst)) % $. This is first exclusive $B$ $b \to c transition.

10.1103/physrevlett.99.191807 article EN Physical Review Letters 2007-11-09

We report a measurement of D0-D0bar mixing in D0->Ks pi+ pi- decays using time-dependent Dalitz plot analysis. first assume CP conservation and subsequently allow for violation. The results are based on 540 fb$^{-1}$ data accumulated with the Belle detector at KEKB $e^+e^-$ collider. Assuming negligible violation, we measure parameters $x=(0.80\pm0.29^{+0.09 +0.10}_{-0.07 -0.14})%$ $y=(0.33\pm0.24^{+0.08 +0.06}_{-0.12 -0.08})%$, where errors statistical, experimental systematic, systematic...

10.1103/physrevlett.99.131803 article EN Physical Review Letters 2007-09-28

Calcitonin is known to inhibit osteoclastic bone resorption through its receptor, which abundantly expressed on the plasma membrane of osteoclasts. Recently, it was reported that calcitonin receptors were coupled both cAMP-dependent protein kinase (PKA) and C (PKC). To examine how PKA PKC pathways are involved in effects calcitonin, we focused changes cytoskeleton murine osteoclast-like multinucleated cells (OCLs) formed vitro. When OCLs cultured dentine slices, they pits ringed structures...

10.1210/endo.137.11.8895334 article EN Endocrinology 1996-11-01

The 800-ton cosmic-ray spectrograph (MUTRON) has been used to measure the sea-level energy spectrum of muons arriving from 86\ifmmode^\circ\else\textdegree\fi{} 90\ifmmode^\circ\else\textdegree\fi{} zenith angles in momentum region 100-20 000 GeV/c. measured muon can be interpreted by using a primary (1.80 ${\mathrm{cm}}^{\ensuremath{-}2}$${\mathrm{s}}^{\ensuremath{-}1}$${\mathrm{sr}}^{\ensuremath{-}1}$${\mathrm{GeV}}^{\ensuremath{-}1}$)${E}^{\ensuremath{-}2.70}\mathrm{dE}$ ($E$ GeV) and...

10.1103/physrevd.29.1 article EN Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D. Particles and fields 1984-01-01

Using a $282\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ data sample collected by the Belle experiment at KEKB ${e}^{+}{e}^{\ensuremath{-}}$ collider, we study ${D}^{0}$ decays to ${K}^{\ensuremath{-}}{\ensuremath{\ell}}^{+}\ensuremath{\nu}$ and ${\ensuremath{\pi}}^{\ensuremath{-}}{\ensuremath{\ell}}^{+}\ensuremath{\nu}$ final states. The flavor momentum are tagged through full reconstruction of recoiling charm meson additional mesons from fragmentation. method provides very good...

10.1103/physrevlett.97.061804 article EN Physical Review Letters 2006-08-11

We present a high-statistics measurement of differential cross sections and the total section for process $\ensuremath{\gamma}\ensuremath{\gamma}\ensuremath{\rightarrow}{\ensuremath{\pi}}^{0}{\ensuremath{\pi}}^{0}$ in kinematic range $0.6\text{ }\text{ }\mathrm{GeV}\ensuremath{\le}W\ensuremath{\le}4.0\text{ }\mathrm{GeV}$ $|\mathrm{cos}{\ensuremath{\theta}}^{*}|\ensuremath{\le}0.8$, where $W$ ${\ensuremath{\theta}}^{*}$ are energy pion scattering angle, respectively,...

10.1103/physrevd.78.052004 article EN Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D, Particles, fields, gravitation, and cosmology 2008-09-12

The differential cross sections of the Σ^{-}p→Λn reaction were measured accurately for Σ^{-} momentum (p_{Σ}) ranging from 470 to 650 MeV/c at J-PARC Hadron Experimental Facility. Precise angular information about was obtained first time by detecting approximately 100 events each step Δcosθ=0.1. show a slightly forward-peaking structure in regions. integrated -0.7≤cosθ≤1.0 as 22.5±0.68 [statistical error(stat.)] ±0.65 [systematic error(syst.)] mb and 15.8±0.83(stat)±0.52(syst)...

10.1103/physrevlett.128.072501 article EN Physical Review Letters 2022-02-15

To compare the health-related quality of life (HRQoL) after radical cystectomy in patients with an ileal conduit or orthotopic neobladder.The study included 85 men who underwent for bladder cancer, comprising 48 neobladder (26 and 22 a colon neobladder) 37 conduit. HRQoL was evaluated using Short Form-36 survey containing 36 questions assessing eight aspects, including physical functioning, role-physical bodily pain, general health, vitality, social role-emotional functioning mental...

10.1046/j.1464-4096.2001.01475.x article EN BJU International 2002-01-01

We present a measurement of the unitarity triangle angle ${\ensuremath{\phi}}_{3}$ using Dalitz plot analysis ${K}_{S}^{0}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ decay neutral $D$ meson from ${B}^{\ifmmode\pm\else\textpm\fi{}}\ensuremath{\rightarrow}{D}^{(*)}{K}^{(*)\ifmmode\pm\else\textpm\fi{}}$ process. The method exploits interference between ${D}^{0}$ and ${\overline{D}}^{0}$ to extract ${\ensuremath{\phi}}_{3}$, strong phase $\ensuremath{\delta}$ ratio $r$ suppressed...

10.1103/physrevd.73.112009 article EN Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D, Particles, fields, gravitation, and cosmology 2006-06-29

10.1016/j.paid.2004.10.002 article EN Personality and Individual Differences 2005-02-02

A high statistics $\mathrm{\ensuremath{\Sigma}}p$ scattering experiment is performed at the J-PARC Hadron Experimental Facility. Momentum-tagged ${\mathrm{\ensuremath{\Sigma}}}^{\ensuremath{-}}\mathrm{s}$ running in a liquid hydrogen target are accumulated by detecting ${\ensuremath{\pi}}^{\ensuremath{-}}p\ensuremath{\rightarrow}{K}^{+}{\mathrm{\ensuremath{\Sigma}}}^{\ensuremath{-}}$ reaction with intensity ${\ensuremath{\pi}}^{\ensuremath{-}}$ beam of 20 M/spill. The differential cross...

10.1103/physrevc.104.045204 article EN Physical review. C 2021-10-28

Objective To compare the health‐related quality of life (HRQoL) after radical cystectomy in patients with an ileal conduit or orthotopic neobladder. Patients and methods The study included 85 men who underwent for bladder cancer, comprising 48 neobladder (26 22 a colon neobladder) 37 conduit. HRQoL was evaluated using Short Form‐36 survey containing 36 questions assessing eight aspects, including physical functioning, role‐physical bodily pain, general health, vitality, social role‐emotional...

10.1046/j.1464-410x.2002.02529.x article EN BJU International 2002-01-01

We present a search for the rare decays B→h(*)ν¯ν, where h(*) stands light meson. A data sample of 535×106 B¯¯¯B pairs collected with Belle detector at KEKB e+e− collider is used. Signal candidates are required to have an accompanying B meson fully reconstructed in hadronic mode and signal side particles consistent single No significant observed we set upper limits on branching fractions 90% confidence level. The B0→K*0ν¯ν B+→K+ν¯ν more stringent than previous constraints, while first...

10.1103/physrevlett.99.221802 article EN Physical Review Letters 2007-11-30

We report measurements of the charmless semileptonic decays B0→π−/ρ−ℓ+ν and B+→π0/ρ0ℓ+ν, based on a sample 2.75×108 BB¯ events collected at ϒ(4S) resonance with Belle detector KEKB e+e− asymmetric collider. In this analysis, accompanying B meson is reconstructed in mode B→D(∗)ℓν, enabling detection signal modes high purity. measure branching fractions B(B0→π−ℓ+ν)=(1.38±0.19±0.14±0.03)×10−4, B(B0→ρ−ℓ+ν)=(2.17±0.54±0.31±0.08)×10−4, B(B+→π0ℓ+ν)=(0.77±0.14±0.08±0.00)×10−4...

10.1016/j.physletb.2007.02.067 article EN cc-by Physics Letters B 2007-03-08

The natural resistance of F1 hybrid mice against parental bone marrow grafts is thought to be mediated by killer (NK)-like effector cells. However, unlike the NK cell activity a wide range tumors and normal cells, characterized immunogenetic specificity controlled set unique noncodominant genes denoted as Hh. Two alternative hypotheses can account for specificity. Thus, may reflect either Hh restriction effectors or gene control mechanisms regulating non-Hh-restricted activity. In this...

10.1084/jem.159.4.1132 article EN The Journal of Experimental Medicine 1984-04-01
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