A5100667526- Particle physics theoretical and experimental studies
- Quantum Chromodynamics and Particle Interactions
- High-Energy Particle Collisions Research
- Particle Detector Development and Performance
- Particle Accelerators and Free-Electron Lasers
- Dark Matter and Cosmic Phenomena
- Neutrino Physics Research
- Computational Physics and Python Applications
- Particle accelerators and beam dynamics
- Superconducting Materials and Applications
- Alzheimer's disease research and treatments
- Nuclear physics research studies
- Medical Imaging Techniques and Applications
- Cosmology and Gravitation Theories
- Black Holes and Theoretical Physics
- Atomic and Subatomic Physics Research
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Pulsars and Gravitational Waves Research
- Anesthesia and Pain Management
- Radiation Detection and Scintillator Technologies
- Liver Disease Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
Nara Institute of Science and Technology
2018-2025
Hokkaido University
1956-2024
Osaka Metropolitan University
2023-2024
IHI Corporation (Czechia)
2024
Kyoto University
2003-2024
High Energy Accelerator Research Organization
2013-2024
The University of Tokyo
2004-2023
Social Insurance Saitama Chuo Hospital
2012-2023
Kawagoe Technical High School
2023
Saitama Medical University
2012-2023
Alzheimer's disease (AD) is a progressive neurodegenerative disorder pathologically characterized by deposition of β-amyloid (Aβ) peptides as senile plaques in the brain. Recent studies suggest that green tea flavonoids may be used for prevention and treatment variety diseases. Here, we report (-)-epigallocatechin-3-gallate (EGCG), main polyphenolic constituent tea, reduces Aβ generation both murine neuron-like cells (N2a) transfected with human “Swedish” mutant amyloid precursor protein...
The cross section for ${e}^{+}{e}^{\ensuremath{-}}\ensuremath{\rightarrow}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}\ensuremath{\psi}(2S)$ between threshold and $\sqrt{s}=5.5\text{ }\text{ }\mathrm{GeV}$ is measured using $673\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ of data on off the $\ensuremath{\Upsilon}(4S)$ resonance collected with Belle detector at KEKB. Two resonant structures are observed in...
The cross section for ${e}^{+}{e}^{\ensuremath{-}}\ensuremath{\rightarrow}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}J/\ensuremath{\psi}$ between 3.8 and $5.5\text{ }\text{ }\mathrm{GeV}/{c}^{2}$ is measured using a $548\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ data sample collected on or near the $\ensuremath{\Upsilon}(4S)$ resonance with Belle detector at KEKB. A peak $4.25\text{ }\mathrm{GeV}/{c}^{2}$, corresponding to so called $Y(4260)$, observed. In addition, there another...
We have recently shown that Alzheimer's disease (AD) transgenic mice given a moderate level of caffeine intake (the human equivalent 5 cups coffee per day) are protected from development otherwise certain cognitive impairment and decrea
This chapter of the report "Flavor in era LHC" Workshop discusses theoretical, phenomenological and experimental issues related to flavor phenomena charged lepton sector conserving CP-violating processes. We review current limits main theoretical models for structure fundamental particles. analyze consequences available data, setting constraints on explicit beyond standard model, presenting benchmarks discovery potential forthcoming measurements both at LHC low energy, exploring options...
The SuperKEKB project requires a positron and electron collider with peak luminosity of 8 × 1035 cm−2 s−1. This is 40 times that the KEKB B-factory, which operated for 11 years up to 2010. an asymmetry-energy double-ring collider; beam energy (LER) 4 GeV (HER) 7 GeV. An extremely small beta function at interaction point (IP) low emittance are necessary. In addition, in order achieve target luminosity, large horizontal crossing angle between two colliding beams adopted, as bunch length much...
We report a measurement of the exclusive e+ e- -->Lambda+_(c)Lambda-_(c) cross section as function center-of-mass energy near Lambda+_(c)Lambda-_(c) threshold. A clear peak with significance 8.2sigma is observed in invariant mass distribution just above With an assumption resonance origin for peak, and width M=[4634 (+8)_(-7)(stat)(+5)_(-8)(syst)] MeV/c(2) Gamma_(tot)=[92 (+40)_(-24)(stat)(+10)_(-21)(syst)] MeV are determined. The analysis based on study events initial-state-radiation...
We report the results of a study charged B decays to D+- pi-+ and D*+- final states using complete D(*) reconstruction. The contributions two-body => D** pi with narrow (j=3/2) broad (j=1/2) have been determined masses widths four measured. This is first observation D*0_0 D'0_1 mesons. analysis based on data sample 65 million barB pairs collected in Belle experiment.
Abstract: The neurohormone melatonin has been reported to exert anti‐β‐amyloid aggregation, antioxidant, and anti‐inflammatory actions in various vitro animal models. To comprehensively determine the potential for long‐term treatment protect Alzheimer’s transgenic mice against cognitive impairment development of β‐amyloid (Aβ) neuropathology, we administered (100 mg/L drinking water) APP + PS1 double (Tg) from 2–2.5 months age their killing at 7.5 months. A comprehensive behavioral battery...
We report a fully inclusive measurement of the flavor changing neutral current decay b --> sgamma in energy range 1.8 GeV < or = E*gamma 2.8 GeV, covering 95% total spectrum. Using 140 fb(-1), we obtain B(b sgamma) (3.55+/-0.32(+0.30+0.11)(-0.31-0.07)) x 10(-4), where errors are statistical, systematic, and from theory corrections. also measure first second moments photon spectrum above (Egamma) 2.292+/-0.026+/-0.034 (E2gamma) - (Egamma)2 0.0305+/-0.0074+/-0.0063 GeV2, statistical systematic.
The Collins effect connects transverse quark spin with a measurable azimuthal dependence in the yield of hadronic fragments around quark's momentum vector. Using two different reconstruction methods, we find evidence statistically significant asymmetries for charged pion pairs e(+)e(-) annihilation at center-of-mass energy 10.52 GeV, which can be attributed to polarization primordial quarks. measurement was performed using sample 79 x 10(6) events collected Belle detector.
We report a measurement of the process $\ensuremath{\gamma}{\ensuremath{\gamma}}^{*}\ensuremath{\rightarrow}{\ensuremath{\pi}}^{0}$ with $759\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ data sample recorded Belle detector at KEKB asymmetric-energy ${e}^{+}{e}^{\ensuremath{-}}$ collider. The pion transition form factor, $F({Q}^{2})$, is measured for kinematical region $4\text{ }{\mathrm{GeV}}^{2}\ensuremath{\lesssim}{Q}^{2}\ensuremath{\lesssim}40\text{ }{\mathrm{GeV}}^{2}$, where...
Malignant lymphomas developing in tissue affected by a long-standing severe inflammatory process of nonautoimmune nature are presented. Two men and woman aged 50, 58, 73 years, were admitted after 22 to 30 year histories pyothorax resulting from artificial pneumothorax for the treatment pulmonary tuberculosis or tuberculous pleuritis. The diagnoses at admission chronic associated with lung mass. Microscopically, tumors diffusely locally proliferated thickened pleura present. A histologic...
Recently, we have shown that green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) exerts a beneficial role on reducing brain Abeta levels, resulting in mitigation of cerebral amyloidosis mouse model Alzheimer disease. EGCG seems to accomplish this by modulating amyloid precursor protein (APP) processing, enhanced cleavage the alpha-COOH-terminal fragment (alpha-CTF) APP and corresponding elevation NH(2)-terminal product, soluble APP-alpha (sAPP-alpha). These effects were associated...
Recent epidemiologic studies suggest that caffeine may be protective against Alzheimer's disease (AD). Supportive of this premise, our previous have shown moderate administration protects/restores cognitive function and suppress
We report a high-statistics measurement of the branching fraction for tau^- --> pi^- pi^0 nu_tau and invariant mass spectrum produced system using 72.2 fb^-1 data recorded with Belle detector at KEKB asymmetric-energy e^+ e^- collider. The obtained is (25.24 +/- 0.01 0.39)%, where first error statistical second systematic. unfolded used to determine resonance parameters rho(770), rho'(1450), rho"(1700) mesons. also use this estimate hadronic (2pi) contribution anomalous magnetic moment muon...
We perform a full amplitude analysis of B0→ψ′K+π− decays, with ψ′→μ+μ− or e+e−, to constrain the spin and parity Z(4430)−. The JP=1+ hypothesis is favored over 0−, 1−, 2− 2+ hypotheses at levels 3.4σ, 3.7σ, 4.7σ 5.1σ, respectively. based on 711 fb−1 data sample that contains 772×106 BB¯ pairs collected Υ(4S) resonance by Belle detector asymmetric-energy e+e− collider KEKB.7 MoreReceived 20 June 2013DOI:https://doi.org/10.1103/PhysRevD.88.074026© 2013 American Physical Society
Amyloid precursor protein (APP) proteolysis is required for production of amyloid-β (Aβ) peptides that comprise β-amyloid plaques in brains Alzheimer’s disease (AD) patients. Recent AD therapeutic interest has been directed toward a group anti-amyloidogenic compounds extracted from plants. We orally administered the brain penetrant, small molecule phenolic compound ferulic acid (FA) to transgenic PSAPP mouse model cerebral amyloidosis (bearing mutant human APP and presenilin-1 transgenes)...
We present the results of an amplitude analysis anti-B0 -> J/psi K- pi+ decays. A new charged charmoniumlike state Zc(4200)+ decaying to is observed with a significance 6.2 sigma. The mass and width are 4196 +31-29 +17-13 MeV/c^2 370 +70-70 +70-132 MeV, respectively; preferred assignment quantum numbers J^P = 1^+. In addition, we find evidence for Zc(4430)+ pi+. based on 711 fb^-1 data sample collected by Belle detector at asymmetric-energy e+ e- collider KEKB.
We measure the branching fraction of B−→τ−¯ντ using full Υ(4S) data sample containing 772×106 B¯¯¯B pairs collected with Belle detector at KEKB asymmetric-energy e+e− collider. Events are tagged by reconstructing one B mesons decaying into hadronic final states, and candidates detected in recoil. find evidence for a significance 3.0 standard deviations including systematic errors B(B−→τ−¯ντ)=[0.72+0.27−0.25(stat)±0.11(syst)]×10−4.Received 16 November...