A5009790812- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Blood Pressure and Hypertension Studies
- Acute Myocardial Infarction Research
- Hormonal Regulation and Hypertension
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac electrophysiology and arrhythmias
- Mechanical Circulatory Support Devices
- Vascular Procedures and Complications
- Pluripotent Stem Cells Research
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Electrolyte and hormonal disorders
- Lung Cancer Treatments and Mutations
- Soil Mechanics and Vehicle Dynamics
- Cardiovascular Disease and Adiposity
- Cardiac Arrest and Resuscitation
- Cardiomyopathy and Myosin Studies
- Kawasaki Disease and Coronary Complications
- Medical Imaging Techniques and Applications
- Chemotherapy-induced cardiotoxicity and mitigation
- Cancer, Hypoxia, and Metabolism
- Atrial Fibrillation Management and Outcomes
- Reproductive Biology and Fertility
Sejong General Hospital
2014-2024
Pusan National University Hospital
2007-2024
Hanyang University
2024
Pusan National University
2015-2023
Weatherford College
2021
Yonsei University
2019
Rural Development Administration
2017
Korea University
2016
Seoul St. Mary's Hospital
1997-2015
Seoul National University
2007
It is known that nanocrystallites can form in shear bands produced during severe bending or high-energy ball milling of thin ribbons a metallic glass. We present direct experimental evidence highly confined and controlled local contact at the ultrafine scale quasi-static nanoindentation bulk glassy metal alloy room temperature also cause nanocrystallization. Atomic force microscopy transmission electron show nucleate around near indents they are same as crystallites formed annealing without...
Purpose. To evaluate the prognostic value of metabolic tumor volume measured on 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging and other clinical factors in patients treated for locally advanced head-and-neck cancer (HNC) at a single institution. Materials methods. Between June 2005 August 2008, 59 with HNC that underwent pretreatment FDG-PET studies received neoadjuvant chemotherapy radiation therapy. Metabolically active regions were delineated PET scans by fixed SUV...
Tumor hypoxia is significant in promoting tumor progression and resistance to therapy, hypoxia‑inducible factor 1α (HIF‑1α) essential the adaptive response of cells hypoxia. The aim present study was investigate expression hypoxic markers evaluate their prognostic significance soft tissue sarcoma (STS). A retrospective analysis 55 patients with STS from Pusan National University Hospital (Busan, Korea) between 1998 2007 conducted, using immunohistochemistry analyze HIF‑1α, carbonic anhydrase...
Background— The aim of this study was to assess whether deferred stenting (DS) reduces infarct size and microvascular obstruction (MVO) compared with immediate (IS) in primary percutaneous coronary intervention for ST-segment–elevation myocardial infarction. Methods Results— From February 2013 August 2015, 114 patients (mean age: 69 years) were randomized into the following 2 groups: DS an intention stent 3 7 days later or IS after reperfusion centers. secondary end points incidence MVO,...
Abstract Background. Dexamethasone-induced hiccup (DIH) is an underrecognized symptom in patients with cancer, and little information available about its treatment. The aims of this study were to investigate the feasibility methylprednisolone rotation as treatment confirm male predominance among those cancer who experienced DIH during chemotherapy. Methods. Persons hiccups chemotherapy receiving dexamethasone presumed have DIH. following algorithmic practice was implemented for antiemetic...
Background and Objectives: Numbness on the hand occurs infrequently after a transradial cardiac catheterization (TRC).The symptom resembles that of neuropathy.We, therefore, investigated prevalence, predicting factors presence neurological abnormalities numbness, using nerve conduction study (NCS).Subjects Methods: From April to December 2013, all patients who underwent TRC were prospectively enrolled.From among these, experienced numbness ipsilateral instructed describe their symptoms...
We investigate to determine whether N-acetylcysteine (NAC) can prevent anthracycline-induced cardiotoxicity.A total of 103 patients were enrolled in this prospective randomized open label controlled trial. They are first diagnosed with breast cancer or lymphoma, who require chemotherapy, including anthracycline like adriamycine epirubicine. Patients the NAC group {n=50; 1200 mg orally every 8 hours starting before and ending after intravenous infusion all chemotherapy cycles (3-6)} control...
Abstract A two-phase flow parametric study on an air induction nozzle with water and as the working fluids is presented. Liquid was supplied at pre-orifice various inlet pressures ranging from 3 to 6 bar. The interaction between molecular level orifice exit leads formation of a strong shear layer that intensified increase in pressure. Thus, it vital regulate ratio intake liquid so generated micro bubbles fit design criteria. CFD analysis conducted using commercial software STAR CCM+ Siemens...
Several reports have suggested that thyrotoxicosis may induce severe coronary artery spasm (CAS). However, there are few data regarding the differences in clinical characteristics of CAS with and without thyrotoxicosis. The aim our study is to compare features thyrotoxicosis.We evaluated 430 consecutive patients [patients (N=32, group I) those (N=398, II)] at a single institute between January 2001 June 2011. We compared presentations, angiographic findings, adverse outcomes (a composite...
Background: The frequency of using veno-arterial extracorporeal membrane oxygenation increased, especially in patients with refractory cardiogenic shock or cardiac arrest. However, data complications are lacking. This study sought to investigate the incidence for acute myocardial infarction arrest and its relationship patient survival. Methods: included 151 consecutive who underwent between 2006 2018 at a single referral center. We divided into those survived 30 days after ( n = 57, 38%;...
With the advent of next-generation sequencing (NGS), targeted is now contributing to decision making for which chemotherapeutics administer cancer patients, especially in refractory and metastatic cancer. Given that most patients with develop resistance chemotherapy have few treatment options, we performed NGS test evaluate efficacy clinical feasibility NGS-based anticancer therapy. We used a gene panel capturing target regions covering 83 cancer-related genes. A total 25 solid tumor were...
We sought to evaluate the impact of final kissing balloon inflation (FKBI) after simple stent implantation for treatment non-left main true coronary bifurcation lesions in patients with acute syndrome (ACS).Whether FKBI should be mandatory lesion is controversial. Besides, ACS who have undergone percutaneous intervention may experience worse prognosis compared stable angina pectoris patients.Two hundred and fifty one eligible (67.7% male, mean age 61.7 ± 10.4 years) were enrolled. The study...
The goal of this study was to compare the efficacy and safety fixed-dose combinations amlodipine/losartan potassium/chlorthalidone (A/L/C) A/L in Korean patients with stage 2 hypertension inadequately controlled by A/L.This an 8-week, randomized double-blind, multicenter, phase III clinical trial. Three hundred forty volunteer were receive A/L/C or A/L. primary end point a change sitting systolic blood pressure (SitSBP) after 8 weeks treatment. As secondary points, SitSBP treatment diastolic...
This study investigated the protective effect of glutathione (GSH), an antioxidant drug, against doxorubicin (DOX)-induced cardiotoxicity. Human cardiac progenitor cells (hCPCs) treated with DOX (250 to 500 nM) showed increased viability and reduced ROS generation apoptosis GSH treatment (0.1 1 mM) for 24 h. In contrast nM group, pERK levels were restored in group co-treated suppression ERK signaling improved hCPCs' survival. Similarly previous results, potency hCPCs 100 which did not affect...
We report a case of colchicine-induced myopathy related to short-term, customary administration colchicine. A 49-year-old male was admitted because muscle weakness and myalgia that had developed 10 days previously. He received renal transplantation 5 years previously took cyclosporine as an immunosuppressant. Two weeks before admission, gout he colchicine (1.2 mg b.i.d) by himself for three days. Colchicine-induced clinically suspected, intake stopped immediately. After that, clinical...
Purpose: Kilt technique can be useful for overcoming the severe angle in endovascular abdominal aortic repair. Thus, we investigate utility of as an modification method.