- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Bladder and Urothelial Cancer Treatments
- Reproductive System and Pregnancy
- Pediatric Urology and Nephrology Studies
- Endometriosis Research and Treatment
- Lung Cancer Diagnosis and Treatment
- Tissue Engineering and Regenerative Medicine
- Histone Deacetylase Inhibitors Research
- Antioxidant Activity and Oxidative Stress
- Peptidase Inhibition and Analysis
- Esophageal Cancer Research and Treatment
- Chemotherapy-induced organ toxicity mitigation
- Electrospun Nanofibers in Biomedical Applications
- Retinoids in leukemia and cellular processes
- Multiple Myeloma Research and Treatments
- Geochemistry and Geologic Mapping
- Cancer, Stress, Anesthesia, and Immune Response
- Glycosylation and Glycoproteins Research
- Hydrocarbon exploration and reservoir analysis
- Inflammatory mediators and NSAID effects
- Advanced Neural Network Applications
- Occupational and environmental lung diseases
- Head and Neck Surgical Oncology
- Reservoir Engineering and Simulation Methods
Obstetrics and Gynecology Hospital of Fudan University
2009-2024
Fudan University
2010-2021
Sun Yat-sen University
2016-2021
Union Hospital
2021
Huazhong University of Science and Technology
2021
The First Affiliated Hospital, Sun Yat-sen University
2016-2021
Zhongshan Hospital
2016-2021
Shaoxing People's Hospital
2021
Sichuan University
2009-2020
Stanford University
2012
Most randomized trials for acute promyelocytic leukemia (APL) have investigated highly selected patients under idealized conditions, and the findings need to be validated in real world. We conducted a population-based study of all APL Zhejiang Province, China, with total population 82 million people, assess generalization all-trans retinoic acid (ATRA) arsenic as front-line treatment. The outcomes were also analyzed. Between January 2015 December 2019, 1,233 eligible included final analysis....
Ovarian cancer has the highest mortality rate of gynaecological cancers. Although cisplatin (CDDP) is an effective treatment for ovarian cancer, recurrence frequent and leads to death. The objective was explore role possible mechanisms platelet-activating factor receptor (PAFR) signalling in CDDP-treated cells.
Abstract Objectives It is essential to understand the molecular basis of ovarian cancer etiology and tumor development provide more effective preventive therapeutic approaches reduce mortality. Particularly, targets pathways involved in early malignant transformation are still not clear. Pro-inflammatory lipids have been reported play significant roles progression metastasis. The major objective this study was explore determine whether platelet activating factor (PAF) receptor associated...
CA125 is the most widely used serum marker for preoperative diagnosis of ovarian cancer. However, elevation not specific to More than 60% patients who have elevated levels do To overcome low specificity CA125, we identified a glycoform that was specifically in cancer and may help further triage with levels.We antibody-lectin ELISA detect various glycoforms. Among 21 lectins tested, VVA, plant lectin preferentially binds Tn antigen, showed significantly stronger binding cancer-derived benign...
This study aimed to evaluate the incidence and predict risk factors of lymph node (LN) metastasis among patients with grossly apparent early-stage epithelial ovarian cancer (EOC).
Ovarian cancer is predominant of epithelial cell origin and often present at an advanced stage with poor prognosis. Most animal models ovarian carcinoma yield thecal/granulose tumors, rather than adenocarcinomas. The best reported induction rate adenocarcinoma in rats 10-45% by implantation 7, 12-dimethylbenz[a]anthracene (DMBA) coated silk suture. We provided improved procedure to construct the model DMBA-coated cloth strip.A sterile suture (as S group) or a piece strip CS was soaked DMBA...
Abstract Gene‐directed enzyme prodrug therapy (GDEPT) is a strategy developed to selectively target cancer cells. However, the clinical benefit limited due its poor gene transfer efficiency. To overcome this obstacle, we took advantage of piggyBac (PB) transposon, natural non‐viral vector that can induce stable chromosomal integration and persistent expression in vertebrate cells, including human determine whether also mediate ovarian constructed PB transposon system simultaneously expresses...
Background: In China, secondary cytoreductive surgery (SCR) has been widely used in ovarian cancer (OC) over the past two decades.Although Gynecologic Oncology Group-0213 trial did not show its overall survival benefit first relapsed patients, questions on patient selection and effect of subsequent targeting therapy are still open.The preliminary data from our pre-SOC1 phase II study showed that selected patients with second relapse who never received SCR at recurrence may surgery.Moreover,...
Abstract OBJECTIVES The cervicothoracic junction is a special section that connects the neck, thoracic cavity, mediastinum and axilla. Tumours in region often invade or compress surrounding tissues organs, which makes surgical treatment difficult. METHODS A retrospective analysis involving 69 patients with tumours at junction. Clinical data regard to manifestation, approach, resection degree, outcome pathological types were collected. RESULTS total of 48 cases asymptomatic 21 ≥1 clinical...
Breast cancer has become the primary factor threatening women's health. Automated breast volume scanner (ABVS) is applied for automatic scanning which meaningful rapid and accurate detection of tumor. However, segmentation tumor regions a huge challenge clinicians from ABVS images since it large image size low data quality. Therefore, we propose novel 3D deep convolutional neural network data. The structure based on U-Net designed with attention mechanism transformer layers to optimize...
You have accessJournal of UrologyGeneral & Epidemiological Trends Socioeconomics: Practice Patterns, Cost Effectiveness II1 Apr 2014MP11-13 PREDICTORS FOR THE USE OF INTRAVESICAL MITOMYCIN-C FOLLOWING TRANSURETHRAL RESECTION BLADDER TUMORS IN UNITED STATES: A POPULATION BASED ANALYSIS Nedim Ruhotina, Jeffrey Leow, Wei Jiang, Benjamin L. Chung, Jonathan Rosenberg, Adam Kibel, Quoc Dien Trinh, and Steven Chang RuhotinaNedim Ruhotina More articles by this author , LeowJeffrey Leow JiangWei...
You have accessJournal of UrologyGeneral & Epidemiological Trends Socioeconomics: Practice Patterns, Cost Effectiveness III1 Apr 2012423 TRENDS IN THE ADOPTION OF ROBOTIC TECHNOLOGY FOR RADICAL CYSTECTOMY A POPULATION-BASED ANALYSIS Steven Chang, Wei Jiang, and Benjamin Chung ChangSteven Chang Boston, MA More articles by this author , JiangWei Jiang ChungBenjamin Stanford, CA View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.489AboutPDF ToolsAdd to favoritesDownload...
311 Background: The adoption of the da Vinci Surgical System (Intuitive Surgical, Inc.) for robotic surgery requires a substantial financial investment by hospitals, acquisition new surgical skills surgeons, and demand from patients. Although benefits this technology have been previously described, prevalence rate robotics in management bladder cancer is not currently known. We performed population-based analysis to determine how introduction has altered cancer. Methods: analyzed...
Ovarian endometrioid carcinoma resembling sex cord-stromal tumor (ECSCSs) is rare.We present a rare case of primary ECSCSs in the left ovary. A 39-year-old female patient had persistent dull pain lower abdomen for more than 1 mo, and she was initially diagnosed with pelvic inflammatory disease at hospital. The received transabdominal hysterectomy, bilateral salpingo-oophorectomy, para-aortic lymph node dissection our hospital finally ECSCSs. After operation, eight courses cisplatinum +...