Michael O’Sullivan

ORCID: 0000-0003-0055-599X
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About
Contact & Profiles
Research Areas
  • Pediatric health and respiratory diseases
  • GDF15 and Related Biomarkers
  • Medical Malpractice and Liability Issues
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Vaccine Coverage and Hesitancy
  • Tryptophan and brain disorders
  • Maternal Mental Health During Pregnancy and Postpartum
  • Advanced biosensing and bioanalysis techniques
  • Viral gastroenteritis research and epidemiology
  • Elder Abuse and Neglect
  • Bacterial Infections and Vaccines
  • Memory and Neural Mechanisms
  • Patient Safety and Medication Errors
  • Healthcare Systems and Practices
  • Agriculture and Rural Development Research
  • Immune responses and vaccinations
  • Suicide and Self-Harm Studies
  • Breastfeeding Practices and Influences
  • Chronic Disease Management Strategies
  • Nanopore and Nanochannel Transport Studies
  • Agricultural Innovations and Practices
  • Intramuscular injections and effects
  • Single-cell and spatial transcriptomics
  • Religion, Spirituality, and Psychology
  • Health, Medicine and Society

The Kids Research Institute Australia
2024-2025

Princess Margaret Hospital for Children
2025

Health Research Board
2019-2023

Trinity College Dublin
2014-2021

Dublin Dental University Hospital
2016

Ollscoil na Gaillimhe – University of Galway
2013

University of Minnesota System
1968

Abstract The locus coeruleus‐noradrenergic (LC–NA) neuromodulatory system has been implicated in a broad array of cognitive processes, yet scope for investigating this system's function humans is currently limited by an absence reliable non‐invasive measures LC activity. Although pupil diameter employed as proxy measure activity numerous studies, empirical evidence relationship between the two lacking. In present study, we sought to rigorously probe and BOLD localized human LC. Simultaneous...

10.1002/hbm.22466 article EN Human Brain Mapping 2014-02-07

Surgical checklists has been shown to improve patient safety and teamwork in the operating theatre. However, despite known benefits of use surgery, some cases practical implementation found be less than universal. A questionnaire methodology was used quantitatively evaluate attitudes theatre staff towards a modified version World Health Organisation (WHO) surgical checklist with relation to: beliefs about levels compliance support, impact on teamwork, barriers checklist. Using theory planned...

10.1186/1754-9493-7-14 article EN cc-by Patient Safety in Surgery 2013-01-01

Background Whole-cell pertussis (wP) and acellular (aP) vaccines evoke different immune responses to vaccine antigens. We compared the effect of a heterologous wP/aP/aP primary series (hereafter mixed wP/aP) versus homologous aP/aP/aP schedule aP-only) on antibody co-administered antigens in infants toddlers. Methods randomised Australian 1:1 ratio receive either wP/aP (pentavalent diphtheria-tetanus-wP-hepatitis B-Haemophilus influenzae type b; DTwP-HepB-Hib at 6 weeks old followed by...

10.1101/2025.02.16.25321528 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2025-02-21

Abstract Background People with intellectual disability die younger than their non‐disabled peers. In recent years, greater attention has been paid to closing the gap. However, evidence that this is being achieved limited by dearth of longitudinal, national data. Method Over 4,000 decedents identified in Irish National Intellectual Disability Database from 2001 2016 were compared deaths general population based on age and gender profiles using death rates standardised mortality ratios. A...

10.1111/jar.12853 article EN cc-by-nc-nd Journal of Applied Research in Intellectual Disabilities 2020-12-30

Prolonged or severe stress can adversely affect older adults' cognitive function, but population-based studies investigating this relationship over time are rare. Previous have largely focused on either evaluated at a single point linked to specific life events. This study aimed investigate whether change in perceived 2 years predicts performance the same period sample of adults. Data from first waves The Irish Longitudinal Study Ageing were analyzed. Five thousand and seventy adults aged 50...

10.1002/smi.2799 article EN Stress and Health 2018-01-30

Caregiving for a person with dementia is frequently used to model the impact of chronic stress on health, including cognitive functioning. However, prevalence typically healthier, self-selecting non-caregiving control groups could contribute picture poorer caregiver performance and overstate negative effects stress. We investigated differences in between caregivers two non-caregivers recruited using different sampling methods.We compared function psychological wellbeing among 252 spousal...

10.1080/13607863.2018.1428937 article EN Aging & Mental Health 2018-01-30

SummaryThe sensitivities of five double-diffusion methods and immunoelectrophoresis for the detection antigen antibody were examined. Although Freer technique was most sensitive these methods, procedures utilizing plastic matrices approached Preer in sensitivity. The advantages disadvantages are discussed.

10.3181/00379727-128-33204 article EN Experimental Biology and Medicine 1968-08-01

A Spirituality Interest Group (SIG) was set up in the School of Nursing and Midwifery, Trinity College Dublin, Republic Ireland (ROI), March 2013. This paper reports on some journey requirements involved developing group. It highlights essential work establishing agreed understandings an objective way order for group to move forward with action. These have contributed group’s success. Outlining arriving at agreements may be use others considering creating similar groups. One key action taken...

10.3390/rel7030030 article EN cc-by Religions 2016-03-15

Investigations into the wider bioecological understanding of dental problems in early childhood are limited national surveys. Classification tree analysis (CTA) was used to explore multilevel interactions among key aspects child and primary caregiver (PCG) psychosocial physical health affecting preschool children. Data were derived from Growing Up Ireland study, a nationally representative sample 9-mo-olds (N = 11,134) 2007/2008 followed up at age 3 y 9,793) 2010/2011. Analysis included PCG...

10.1177/2380084416651834 article EN JDR Clinical & Translational Research 2016-06-10

Remission is the desired outcome following OIT as it allows individuals to discontinue treatment and eat allergen freely. Early initiation of in infants toddlers has been embraced an approach increase likelihood remission. However, there no high-quality evidence supporting younger age independent factor driving remission; available studies are limited by small samples subjects lack adjustment for confounding covariates, particularly peanut-specific IgE (sIgE) levels which closely correlated...

10.22541/au.172507614.42068122/v1 preprint EN Authorea (Authorea) 2024-08-31

<h3>Objectives</h3> This review investigated the design features of vaccine injury redress programmes that are thought to impact on operating costs, timely access compensation, number applicants, and volume costs awards. In addition, we ascertained if such enjoy public acceptance. Vaccine available in 20 jurisdictions; only 11 jurisdictions have completed detailed papers their set up operation, namely, China, Denmark, Finland, Japan, Korea, Norway, New Zealand, Sweden, Taiwan, UK, USA....

10.1136/bmjebm-2019-ebmlive.14 article EN Oral Presentations 2019-07-01

A major challenge in the context of increasing aging population is to identify a method identifying cognitive dysfunction at earliest possible opportunity, preferably marker that blood-based and therefore amenable assessment on longitudinal basis. In this study, we identified 2 cohorts healthy older adults were classified as IQ-memory consistent (n=47) or discrepant (n=28; IQ-con, IQ-dis) basis their performance Wechsler Memory Scale story recall test relative National Adult Reading Test. We...

10.1016/j.jalz.2017.06.1336 article EN Alzheimer s & Dementia 2017-07-01

Abstract Background In Ireland, over 53,000 older adults are supported in their community by formal home support, amounting to an estimated 19 million care hours annually. There is a growing need move beyond care, more proactive approaches maintain physical function. feasibility study, we delivered the ‘Care Move’ (CTM) programme through existing support services. The aim of present qualitative study was explore experience and perceptions Health Care Assistants (HCAs), who were trained in,...

10.1093/ageing/afab216.199 article EN Age and Ageing 2021-11-01
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