- Air Quality and Health Impacts
- Carcinogens and Genotoxicity Assessment
- Energy and Environment Impacts
- Toxic Organic Pollutants Impact
- Cancer Research and Treatments
- Atmospheric chemistry and aerosols
- Climate Change and Health Impacts
- Cancer Immunotherapy and Biomarkers
- Vehicle emissions and performance
- Air Quality Monitoring and Forecasting
- Environmental Sustainability and Education
- Environmental Toxicology and Ecotoxicology
- Escherichia coli research studies
- Cancer, Lipids, and Metabolism
- Gut microbiota and health
- Pharmacological Effects of Natural Compounds
- Healthcare and Environmental Waste Management
- Dye analysis and toxicity
- Cannabis and Cannabinoid Research
- Indigenous Health and Education
- Phytochemistry Medicinal Plant Applications
- Chromium effects and bioremediation
- Birth, Development, and Health
- Prenatal Substance Exposure Effects
- Microscopic Colitis
Onco Lille
2022-2025
Inserm
2023-2025
Laboratoire de Physiologie Cellulaire
2022-2024
Université de Lille
2024
Universidade de São Paulo
2015-2022
Institut Pasteur de Lille
2020
Universidade Cidade de São Paulo
2017
Universidade Federal do Rio Grande do Norte
2011-2015
Universidade Brasil
2015
The Brazilian Amazon represents about 40% of the world's remaining tropical rainforest. However, human activities have become important drivers disturbance in that region. majority forest fire hotspots arc due to deforestation are impacting health local population over 10 million inhabitants. In this study we characterize western Amazonia biomass burning emissions through quantification 14 Polycyclic Aromatic Hydrocarbons (PAHs), Organic Carbon, Elemental Carbon and unique tracers such as...
Most of the studies on air pollution focus emissions from fossil fuel burning in urban centers. However, approximately half world's population is exposed to caused by biomass emissions. In Brazilian Amazon population, over 10 million people are directly high levels pollutants resulting deforestation and agricultural fires. This work first study present an integrated view effects inhalable particles burning. Exposing human lung cells particulate matter smaller than µm (PM
Particulate matter (PM) exposure is a leading global human health risk. In this study, water-soluble oxidative potential (OP) and intracellular reactive oxygen nitrogen species (ROS/RNS) production were measured for open biomass burning aerosol collected from the Brazilian Amazon. Compared to ambient samples Atlanta laboratory-generated secondary organic (SOA), had comparable OP induced higher levels of ROS/RNS. regressed ranges factors resolved using source apportionment in prior studies,...
Air pollution represents a considerable threat to health worldwide. The São Paulo Metropolitan area, in Brazil, has unique composition of atmospheric pollutants with population nearly 20 million people and 9 passenger cars. It is long known that exposure particulate matter less than 2.5 µm (PM2.5) can cause various effects such as DNA damage. One the most versatile defense mechanisms against accumulation damage nucleotide excision repair (NER), which includes XPC protein. However, by NER...
Intratumoral bacteria flexibly contribute to cellular and molecular tumor heterogeneity for supporting cancer recurrence through poorly understood mechanisms. Using spatial metabolomic profiling technologies 16SrRNA sequencing, we herein report that right-sided colorectal tumors are predominantly populated with Colibactin-producing
Air pollution is a public health concern that has been associated with adverse effects on the development and functions of central nervous system (CNS). However, studies exposure to pollutants CNS across entire developmental period still remain scarce. In this study, we investigated impacts prenatal and/or postnatal fine particulate matter (PM2.5) from São Paulo city, brain structure behavior juvenile male mice. BALB/c mice were exposed PM2.5 concentrated ambient particles (CAP) at daily...
The Sao Paulo Metropolitan Area is a unique case worldwide due to the extensive use of biofuel, particularly ethanol, by its large fleet nearly 8 million cars. Based on source apportionment analysis Organic Aerosols in downtown Paulo, and using ethanol as tracer passenger vehicles, we have identified primary emissions from light-duty-vehicles (LDV) heavy-duty-vehicles (HDV), well secondary process component. Each those factors mirror relevant or this densely occupied area. Using predictors...
Periodic behaviors in plants are biological events that determine the successful development and reproduction of individuals plant species can be investigated through phenological studies. In this context, a study tree Croton floribundus Spreng., Cedrela fissilis Vell., Machaerium nyctitans (Vell) Brenth. villosum Vogel. was carried out by us an Atlantic Forest fragment located Federal Institute Southern Minas Gerais - Campus Muzambinho, which is inserted region with well-defined double...
Summary Background Colorectal cancer (CRC) results from the accumulation of mutations and epigenetic changes in gut epithelial cells likely due to microbiota dysbiosis. However, limited research has been done explore link between host tumour dysbiosis disease outcome. Methods The mechanisms influencing outcomes 97 colorectal patients, including 13 with Lynch syndrome, 20 inflammatory bowel (IBD), 64 sporadic cases, were analyzed using a multiomics approach. These patients categorized into...
Retene (RET) is the most abundant polycyclic aromatic hydrocarbon (PAH) released upon burning of cellulose, although it not considered as one priority PAHs and included for risk assessments by US Environmental Protection Agency (US-EPA). There are only a few studies concerning toxic effects RET. To best our knowledge, this study first to examine whether RET, in an environmental concentration, plays crucial role induction oxidative stress A549 lung cell line, its consequence such mutagenicity...
Abstract This special issue of URBE dedicated to Ecological Urbanism focuses on the role architects, landscape designers and urban planners can play in promoting healthier cities Latin America. In this paper, we survey some empirical evidence that links built environment with particular health outcomes. For many centuries, settlements were associated adverse outcomes, especially related untreatable epidemics. As science disease transmission developed throughout nineteenth century,...