A5029883088- Blood Pressure and Hypertension Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Health and Disease Prevention
- Diabetes Treatment and Management
- Cardiac Arrhythmias and Treatments
- Diet and metabolism studies
- Atrial Fibrillation Management and Outcomes
- Diabetes Management and Research
- Heart Rate Variability and Autonomic Control
- Cardiac electrophysiology and arrhythmias
- Retinal Diseases and Treatments
- Cardiovascular Disease and Adiposity
- Thermoregulation and physiological responses
- Cardiovascular Health and Risk Factors
- Gout, Hyperuricemia, Uric Acid
- Diabetes Management and Education
- Liver Disease Diagnosis and Treatment
- Retinal Imaging and Analysis
- Alcohol Consumption and Health Effects
- Chronic Disease Management Strategies
- Hemodynamic Monitoring and Therapy
- Obesity, Physical Activity, Diet
- Pharmacology and Obesity Treatment
- Nutritional Studies and Diet
- Body Image and Dysmorphia Studies
Yuxian People's Hospital
2010-2025
Xian Yang Central Hospital
2021-2025
National Health and Family Planning Commission
2024
National Clinical Research
2024
Shanghai Jiao Tong University
2024
Taizhou Second People's Hospital
2022-2023
BackgroundEffective targets for systolic blood-pressure control in patients with type 2 diabetes are unclear.MethodsWe enrolled 50 years of age or older diabetes, elevated blood pressure, and an increased risk cardiovascular disease at 145 clinical sites across China. Patients were randomly assigned to receive intensive treatment that targeted a pressure less than 120 mm Hg standard 140 up 5 years. The primary outcome was composite nonfatal stroke, myocardial infarction, hospitalization...
Introduction Early screening for diabetic retinopathy (DR) with an efficient and scalable method is highly needed to reduce blindness, due the growing epidemic of diabetes. The aim study was validate artificial intelligence-enabled DR investigate prevalence in adult patients diabetes China. Research design methods prospectively conducted at 155 centers A non-mydriatic, macula-centered fundus photograph per eye collected graded through a deep learning (DL)-based, five-stage classification....
Visceral obesity is associated with high cardiovascular events risk in type 2 diabetes mellitus (T2DM). Whether normal-weight visceral will pose a higher atherosclerotic disease (ASCVD) than body mass index (BMI)-defined overweight or obese counterparts without remains unclear. We aimed to explore the relationship between general and 10-year ASCVD patients T2DM.Patients T2DM (6997) who satisfied requirements for inclusion were enrolled. Patients considered have normal weight when 18.5 kg/m2...
The optimal strategy for persistent atrial fibrillation (PerAF) is poorly defined. We conducted a multicentre, randomized, prospective trial to compare the outcomes of different ablation strategies PerAF.We enrolled 450 patients and randomly assigned them in 1:1:1 ratio undergo pulmonary vein isolation subsequently following three strategies: anatomical guided (ANAT group, n = 150), electrogram (EGM extensive electro-anatomical (EXT 150). primary endpoint was freedom from (AF) lasting longer...
The purpose of this study was to investigate the relationships between generalized, abdominal, and visceral fat obesity prevalence gout in patients with type 2 diabetes mellitus (T2DM). Data were obtained from electronic medical databases National Metabolic Management Center (MMC) Yuhuan Second People's Hospital Taizhou Central (Taizhou University Hospital) September 2017 June 2023. Four indicators analyzed: waist circumference (WC), waist-to-hip ratio (WHR), body mass index (BMI), area...
Abstract The May Measurement Month (MMM) campaign was carried out in China 2022 with the aim of raising awareness raised blood pressure (BP). Here, we report findings campaign. Adults aged ≥ 18 years were recruited opportunistically at 30 provinces. Three seated BP readings taken for each participant, along completion a questionnaire on demographics, lifestyle factors, and comorbidities. Hypertension defined as systolic 140 mmHg and/or diastolic 90 or being antihypertensive medication....
Current guidelines for the optimal ablation strategy persistent atrial fibrillation(PerAF) remain unclear. While our previous RCT confirmed favorable prognosis of aggressive ablation, real-world evidence is still lacking. Among 4,833 PerAF patients undergoing catheter at 10 centers, two groups were defined: Regular Ablation(PVI-only or PVI plus anatomical ablation) and Aggressive Ablation(anatomical electrogram-guided ablation), with 1,560 each after propensity score(PS) matching. The...
To determine whether the follow-up frequency for type 2 diabetes mellitus (T2DM) patients in National Metabolic Management Centers (MMCs) leads to different clinical outcomes.
Abstract Background Atherosclerosis is a common complication in patients with type 2 diabetes (T2DM). Multiple factors are involved the development and progress of atherosclerosis. We evaluated association weekly sedentary time (WST) carotid plaque formation. Methods After data cleaning, total 26 664 participants T2DM from 10 National Metabolic Management Centers (MMCs) June 2017 to April 2021 were enrolled. Self‐reported lifestyle including WST, sleeping time, smoking drinking information,...
To investigate the different efficacies of glycemic control between basal and premixed insulin in participants with type 2 diabetes (T2DM) when non-insulin medications fail to reach treatment targets.This was a prospective, large-scale, real-world study at 10 centers China. Between June 2017 2021, we enrolled 1104 T2DM initiated either once-daily or twice-daily glycosylated hemoglobin (HbA1c) target not met after least two agents were administered. A Cox proportional hazards regression model...
With the decreasing age of type 2 diabetes mellitus (T2DM) onset, incidence diabetic complications is gradually increasing. We evaluated independent effect at onset on retinopathy (DR) development. A total 7472 patients with T2DM were enrolled in National Metabolic Management Center from September 2017 to May 2022. Anthropometry data, laboratory reports, and medical history collected. The association DR was analyzed using multivariable logistic regression models. In addition, a stratified...
We reported findings from participants screened during the May Measurement Month 2021 in China, which aimed to raise awareness of raised blood pressure (BP), and investigate risk factors BP. The study were adults (≥18 years), ideally whom BP had not been measured previous year. Blood was three times consecutively with 1 min intervals sitting position, using a validated upper-arm cuff automated monitor (Omron HEM-7081IT), transmitted central cloud database via smartphone app. measurement...
To investigate the impact of visceral adipose tissue (VAT) on atherosclerosis in type 2 diabetes patients with normal bodyweight (OB[-]) Chinese population, and to further assess sex-age differences between them.A total 8,839 from two National Metabolic Management Centers China were included this study. Participants classified into four groups by fat area (VFA; cm2 ) body mass index (BMI; kg/m2 ): VFA < 100 BMI 23.9 (VA[-]OB[-]), ≥ (VA[-]OB[+]), (VA[+]OB[-]), (VA[+]OB[+]). Atherosclerosis...
Abstract Background “Obesity paradox” occurs in type 2 diabetes mellitus (T2DM) patients when body mass index (BMI) is applied to define obesity. We examined the association of visceral fat area (VFA) as an obesity measurement with arterial stiffness seven ideal cardiovascular health metrics (ICVHMs). Methods A total 29 048 were included analysis from June 2017 April 2021 10 sites National Metabolic Management Centers. ICVHMs modified recommendations American Heart Association....
To investigate the arterial stiffness (AS) risk within urinary albumin-to-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) categories joint effect between kidney disease parameters metabolic goal achievement on AS in adult people with type 2 diabetes (T2D).
Objectives: Masked hypertension is associated with target organ damage and adverse outcomes. However, up to now there no interventional evidence that antihypertensive therapy will be beneficial the patients. Design methods: The ANTIhypertensive treatment in MASKed for protection (ANTI-MASK) trial a multicenter, randomized, double-blind, placebo-controlled clinical (NCT02893358). Eligible patients were 30 70 years old, had untreated masked at least one sign of (TOD). was defined as normal...
Abstract Aims To explore the effects of six months moderate‐intensity aerobic exercise on pancreatic fat content and its impact β‐cell function. Materials Methods A total 106 patients with type 2 diabetes mellitus were randomized to either a training group (three times week, including 5 min warm‐up, 50 dancing, relaxation, n = 53) or control ( 6‐month intervention. The primary endpoint was change in content. An intention‐to‐treat analysis conducted. Results Eighty‐six completed study 43...
Abstract Introduction Diabetes mellitus (DM) and gout cohabitation severely reduces patient life quality while raising financial burden on individual society. The aim of this study was to elucidate the association between physical activity (PA) prevalence among type 2 DM (T2DM) hyperuricemia (HUA) patients. Methods In all, we recruited 2291 T2DM patients with HUA. Among them, 448 had 1843 did not. We collected data, such as anthropometry, laboratory reports, medical history, for our...
This study was developed with the goal of clarifying whether there is any relationship between type 2 diabetes mellitus (T2DM) age onset and clinical outcomes for patients in National Metabolic Management Centers (MMC).
Abstract Objective This study investigated the association of economic status with metabolic index control in type 2 diabetes mellitus (T2DM) patients. Methods In total, 37 454 T2DM patients from 10 National Metabolic Management Centers China were recruited and categorized into two groups: a high‐gross domestic product (GDP) group ( n = 23 993) low‐GDP 13 461). Sociodemographic characteristics, medical histories, lifestyle factors recorded. Logistic regression interaction analysis performed...
Masked hypertension is associated with target organ damage and adverse outcomes. However, up to now there no interventional evidence that antihypertensive therapy will be beneficial the patients.The ANTIhypertensive treatment in MASKed for protection (ANTI-MASK) trial a multicenter, randomized, double-blind, placebo-controlled clinical (NCT02893358). Eligible patients were 30 70 years old, had untreated masked at least one sign of (TOD). was defined as normal office blood pressure (BP, <...