Milena Maule
A5049555886- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- Health, Environment, Cognitive Aging
- Neonatal Respiratory Health Research
- Air Quality and Health Impacts
- Occupational and environmental lung diseases
- Lymphoma Diagnosis and Treatment
- COVID-19 epidemiological studies
- Global Cancer Incidence and Screening
- Glioma Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Electromagnetic Fields and Biological Effects
- COVID-19 and Mental Health
- Cancer Risks and Factors
- Neuroblastoma Research and Treatments
- Birth, Development, and Health
- Radiation Dose and Imaging
- Family Support in Illness
- Congenital Diaphragmatic Hernia Studies
- Neonatal and Maternal Infections
- COVID-19 Clinical Research Studies
- Infant Nutrition and Health
- Statistical Methods and Bayesian Inference
- Cutaneous lymphoproliferative disorders research
- Nutritional Studies and Diet
University of Turin
2016-2025
Piedmont Reference Center for Epidemiology and Cancer Prevention
2016-2025
University of Verona
2024
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2013-2023
Fondazione IRCCS Istituto Nazionale dei Tumori
2017-2022
Fondazione Ricerca Molinette
2020-2022
University of Ottawa
2021
Universidade do Porto
2021
Barcelona Institute for Global Health
2021
Universitat Pompeu Fabra
2021
Advanced-stage mycosis fungoides (MF; stage IIB to IV) and Sézary syndrome (SS) are aggressive lymphomas with a median survival of 1 5 years. Clinical management is based; however, there wide range outcome within stages. Published prognostic studies in MF/SS have been single-center trials. Because the rarity MF/SS, only large collaboration would power study identify independent markers.
Invasive candida infections are a major cause of morbidity and mortality in preterm infants. We performed multicenter, randomized, double-blind, placebo-controlled trial fluconazole for the prevention fungal colonization infection very-low-birth-weight neonates.
Lactoferrin is a mammalian milk glycoprotein involved in innate immunity. Recent data show that bovine lactoferrin (bLF) prevents late-onset sepsis preterm very low birth weight (VLBW) neonates.This secondary analysis of from multicenter randomized controlled trial where VLBW neonates randomly received bLF (100 mg/day; group A1), + Lactobacillus rhamnosus GG (10(6) colony-forming units per day; A2), or placebo (group B) for 6 weeks. Here we analyze the incidence rates fungal colonization,...
Early life is an important window of opportunity to improve health across the full lifecycle. An accumulating body evidence suggests that exposure adverse stressors during early leads developmental adaptations, which subsequently affect disease risk in later life. Also, geographical, socio-economic, and ethnic differences are related inequalities from onwards. To address these public challenges, many European pregnancy childhood cohorts have been established over last 30 years. The enormous...
To provide values of retinal vessel density (VD) in the three capillary plexuses, foveal avascular zone (FAZ) area, and layer thickness a cohort healthy subjects.The optical coherence tomography angiography maps 148 eyes 84 subjects, aged 22 to 76 years, were analyzed for measuring VD using Optovue device comprising projection artifact removal algorithm. Foveal metrics measured, relationship between findings age, sex, image quality was studied.The deep plexus showed lowest (31.6% ± 4.4%) all...
Abstract In causal inference, parametric models are usually employed to address questions estimating the effect of interest. However, rely on correct model specification assumption that, if not met, leads biased estimates. Correct is challenging, especially in high-dimensional settings. Incorporating Machine Learning (ML) into analyses may reduce bias arising from misspecification, since ML methods do require a functional form relationship between variables. when predictions directly plugged...
BackgroundEnvironmental asbestos pollution can cause malignant mesothelioma, but few studies have involved dose–response analyses with detailed information on occupational, domestic, and environmental exposures.ObjectivesIn the present study, we examined spatial variation of mesothelioma risk in an area high levels from industrial plant, adjusting for occupational domestic exposures.MethodsThis population-based case–control study included 103 incident cases 272 controls 1987–1993 around...
Background The aim of this study was to describe the patterns marriage and parenthood in a cohort childhood cancer survivors included Off-Therapy Registry maintained by Italian Association Pediatric Hematology Oncology.Design Methods We analyzed 6,044 patients diagnosed with between 1960 1998, while aged 0 14 years who were 18 old or older December 2003. They followed up through regional vital statistics registers until death end follow (October 30, 2006), whichever occurred first, their...
The rapid increase in mobile phone use young people has generated concern about possible health effects of exposure to radiofrequency (RF), extremely low frequency (ELF) electromagnetic fields (EMF). MOBI-Kids, a multinational case-control study, investigates the potential childhood and adolescent EMF from communications technologies on brain tumor risk 14 countries. which aims include approximately 1,000 cases aged 10-24 years two individually matched controls for each case, follows common...
The PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) study is a prospective analysis of an international database. Here we examine front-line treatments and quality life (QoL) in patients with newly diagnosed mycosis fungoides (MF).
Survivors of childhood leukemia and lymphoma experience high risks second malignant neoplasms. We quantified such risk using a large dataset from 13 population-based cancer registries.The registries provided individual data on cases leukemia, Hodgkin lymphoma, non-Hodgkin occurring in children aged 0-14 years subsequent neoplasms for different time periods 1943 to 2000. Risks were assessed through standardized incidence ratios (SIRs) corresponding 95% confidence intervals (CIs), the rates...
Background: We have previously demonstrated efficacy against fungal colonization and infection of fluconazole prophylaxis that was routinely administered since 2001 in our ICU for preterm infants <1500 g at birth (VLBW). With prolonged use, concerns exist the emergence acquired resistance Candida subspecies are natively fluconazole-resistant (NFR), mostly glabrata krusei. Methods: evaluated retrospectively all clinical surveillance isolates obtained from VLBW NICU during a 10-year period...
OBJECTIVE To investigate age-period-cohort effects on the temporal trend of type 1 diabetes in children age 0–14 years Italian registries. RESEARCH DESIGN AND METHODS This report is based 5,180 incident cases period 1990–2003 from Registry for Type Diabetes Mellitus Italy (RIDI). Multilevel (random intercept) Poisson regression models were used to model sex, age, calendar time, and birth cohorts trends, taking into account registry-level variance component. RESULTS The incidence rate was...