A5079981264- Cervical Cancer and HPV Research
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Intraoperative Neuromonitoring and Anesthetic Effects
- Meningioma and schwannoma management
- EEG and Brain-Computer Interfaces
- Telomeres, Telomerase, and Senescence
- Intracranial Aneurysms: Treatment and Complications
- Advanced Neuroimaging Techniques and Applications
- Endometriosis Research and Treatment
- Breast Cancer Treatment Studies
- HER2/EGFR in Cancer Research
- Cardiac Arrest and Resuscitation
- Epilepsy research and treatment
- Glioma Diagnosis and Treatment
- Estrogen and related hormone effects
- Gastric Cancer Management and Outcomes
- AI in cancer detection
- Intraperitoneal and Appendiceal Malignancies
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Uterine Myomas and Treatments
- Breast Implant and Reconstruction
Azienda Ospedaliero-Universitaria Careggi
2006-2024
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori
2016-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2024
University of Florence
1988-2024
Ospedale G.B. Morgagni - L.Pierantoni
2005-2023
Carlo Forlanini Hospital
2020
University of Bologna
1991-2007
Laboratório Bacchi
1998-2003
European Institute of Oncology
2002
Ripamonti
2002
Although standard treatment for advanced epithelial ovarian cancer (EOC) consists of surgical debulking and intravenous platinum- taxane-based chemotherapy, favorable oncological outcomes have been recently reported with the use cytoreductive surgery (CRS) hyperthermic intraperitoneal chemotherapy (HIPEC). The aim study was to analyze feasibility results CRS HIPEC in patients EOC.This is an open, prospective phase 2 including primary or recurrent peritoneal carcinomatosis due EOC....
It is unknown whether human papillomavirus (HPV) status impacts the prognosis of early stage cervical glandular lesions. This study assessed recurrence and survival rates in situ/microinvasive adenocarcinomas (AC) according to HPV during a 5-year follow-up. The data were retrospectively analyzed women with available testing before treatment. One hundred forty-eight consecutive analyzed. number HPV-negative cases was 24 (16.2%). rate 100% all participants. 7.4% (11 cases, including four...
OBJECTIVE The onco-functional balance represents the primary goal in neuro-oncology. increasing use of navigated transcranial magnetic stimulation (nTMS) allows noninvasive characterization cortical functional anatomy, and its reliability for motor language mapping has previously been validated. Calculation arithmetic processing not studied with nTMS so far. In this study, authors present their preliminary data concerning calculation. METHODS designed a monocentric prospective adopting an...
Simple summary Low-grade serous ovarian cancer (LGSOC) represents an uncommon histotype of (accounting for approximately 5% all cancer) with a distinct behavior compared to its high-grade counterpart, characterized by better prognosis and low response rate chemotherapeutic agents. Similar cancer, cytoreductive surgery is considered crucial patient survival. This retrospective study aimed analyze the outcomes women affected advanced stages (III–IV FIGO) LGSOC from two high-volume oncological...
To evaluate the potential use of immunohistochemical expression telomerase and measurement its activity as diagnostic tools in uterine cervix.The fluorescent telomeric repeat amplification protocol (TRAP) assay was used to a series 43 cervical scrapings. Twenty five cases were cytologically classified inflammatory, and/or metaplastic, acanthotic, 18 presented cell alterations compatible with mild, moderate, or severe intraepithelial neoplasia (CIN). Immunohistochemistry performed on...
Abstract BACKGROUND Y-stenting is an effective but challenging approach for wide-neck aneurysms. PulseRider (PR) (Pulsar/Cerenovus) a new device designed to provide scaffolding during coiling has never been compared with other techniques. OBJECTIVE To compare the immediate and 6-mo results of vs PR assisted coiling. METHODS A total 105 consecutive patients were retrospectively divided into 2 groups (73 32 PR). All underwent angiographic follow-up. We evaluated if some anatomical features...
Two groups of subjects, matched for age, were studied. The first group consisted 190 healthy the second, 60 patients with vertebrobasilar transient ischemic attacks (TIAs), 22 whom underwent angiography. After it was ascertained that findings from continuous-wave (cw) Doppler carotid and vertebral arteries, performed in standard position, normal, examination then done De Kleyn's velocity signal being detected at mastoidal slopes. abnormal classified into two groups: "loss diastolic signal"...
Ovarian cancer (OC) remains relatively rare, although it is among the top 4 causes of death for women younger than 50. The aggressive nature disease and its often late diagnosis with peritoneal involvement have an impact on prognosis. current scientific literature presents ambiguous or uncertain indications management carcinosis (PC) from OC, both owing to lack sufficient data their heterogeneity consistency. Therefore, Italian Society Surgical Oncology (SICO), Obstetrics Gynaecology,...
Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer. Several hospitals throughout region provide primary treatment for these patients and it well know that quality correlated to hospital delivers. The aim of this study was investigate management EOC in a Region North Italy (Emilia-Romagna, Italy). A multidisciplinary group made up 11 physicians 3 biostatisticians formed 2009 perform clinical audits order identify indicators develop Region-wide workup accordance with...
The purpose of this study was to evaluate the clinical impact oxaliplatin, leucovorin, and 5-fluorouracil (FOLFOX-4) chemotherapy in terms response rate, progression-free/overall survival (PFS/OS) safety profile patients with heavily pretreated recurrent epithelial ovarian cancer. Clinical data were reviewed 29 who received FOLFOX-4 as more than third-line chemotherapy, consisting 85 mg/m2 200 bolus 400 on day 1 5-fluorouracil, followed by a 22-h infusion 600 for 2 consecutive days every 3...
Objective: The present study aimed to assess long-term follow-up outcomes in women with situ/microinvasive adenocarcinoma (AC) of the uterine cervix treated conservatively. Methods: Retrospective multi-institutional including early glandular lesions and 5-year undergoing fertility-sparing treatment. Independent variables associated recurrence were evaluated. Logistic regression analysis Kaplan–Meier survival Logrank test performed. Results: Of 269 diagnosed AC, 127 participants underwent...
Objectives Amplification of human telomerase is known to be associated with cervical tumorigenesis, although its role in tumor progression lesions still unclear. We aimed evaluate the predicting evolution lesions. Methods A total 50 tissue samples taken by biopsy or conization once repeatedly from 17 patients over a 14-year follow-up was analyzed using fluorescence situ hybridization (FISH) for hTERC gene alterations and immunohistochemistry (IHC) hTERT expression. The accuracy biomarkers...