Jian Wang

ORCID: 0000-0003-3967-470X
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About
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Research Areas
  • Total Knee Arthroplasty Outcomes
  • Orthopaedic implants and arthroplasty
  • Orthopedic Infections and Treatments
  • Osteoarthritis Treatment and Mechanisms
  • Hip disorders and treatments
  • Knee injuries and reconstruction techniques
  • Shoulder Injury and Treatment
  • Anesthesia and Pain Management
  • Hip and Femur Fractures
  • Bone Tissue Engineering Materials
  • Rheumatoid Arthritis Research and Therapies
  • Spondyloarthritis Studies and Treatments
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Radiomics and Machine Learning in Medical Imaging
  • Lung Cancer Treatments and Mutations
  • Lower Extremity Biomechanics and Pathologies
  • Healthcare and Venom Research
  • Cancer Immunotherapy and Biomarkers
  • Myasthenia Gravis and Thymoma
  • Bone fractures and treatments
  • Tendon Structure and Treatment
  • Traditional Chinese Medicine Studies
  • Blood transfusion and management
  • COVID-19 Clinical Research Studies

Southern Medical University
2016-2025

Nanfang Hospital
2016-2025

Changchun University of Chinese Medicine
2024

Shandong Provincial Hospital
2023-2024

Shandong University
2022-2024

Guiyang Medical University
2023-2024

Affiliated Hospital of Guizhou Medical University
2024

Wuhan University
2024

Wuhan Donghu University
2024

Beijing University of Chinese Medicine
2020-2023

Over the years, electroconductive hydrogels (ECHs) have been extensively applied for stimulating nerve regeneration and restoring locomotor function after peripheral injury (PNI) with diabetes, given their favorable mechanical electrical properties identical to endogenous tissue. Nevertheless, PNI causes loss of inflammatory pain, especially in diabetic patients. It has established that bone marrow stem cells-derived exosomes (BMSCs-Exos) analgesic, anti-inflammatory tissue properties....

10.1016/j.bioactmat.2023.02.024 article EN cc-by-nc-nd Bioactive Materials 2023-03-04

Purpose: Given that autologous bone graft for defects is limited by insufficient supply and morbidity at the donor site, developing biomimetic materials as an alternative has gained consistent attention. However, obstacles in designing bone-mimetic could integrate nature of extracellular matrix, osteogenic cells, osteoinductive ingredients with a fast convenient strategy still exist. Methods: This study designed fabricated mesenchymal stem cell (MSC)-laden, nanohydroxyapatite (HAP),...

10.2147/ijn.s321387 article EN cc-by-nc International Journal of Nanomedicine 2021-08-01

Objective: A prospective, multicenter, randomized controlled trial was conducted to explore the short-term effect of a new robotic-assisted total knee arthroplasty (TKA) system, and clinical radiographic effectiveness between system conventional TKA were compared analyzed. Materials Methods: Overall, 144 patients randomly divided into two groups, wherein 72 underwent using robotic‑assisted TKA. The demographic data parameters collected. factors influencing postoperative hip–knee–ankle (HKA)...

10.1097/js9.0000000000000002 article EN cc-by-nc-nd International Journal of Surgery 2023-03-01

Abstract: The development of metallic joint prostheses has been ongoing for more than a century alongside advancements in hip and knee arthroplasty. Among the materials utilized, Cobalt-Chromium-Molybdenum (Co-Cr-Mo) Titanium-Aluminum-Vanadium (Ti-Al-V) alloys are predominant prosthesis construction, predominantly due to their commendable biocompatibility, mechanical strength, corrosion resistance. Nonetheless, over time, physical wear, electrochemical corrosion, inflammation induced by...

10.2147/ijn.s459255 article EN cc-by-nc International Journal of Nanomedicine 2024-06-01

At present, effective fixation and anti-infection implant materials represent the mainstay for treatment of open fractures. However, external can cause nail tract infections is ineffective fixing small fracture fragments. Moreover, closed reduction internal during early stage injury lead to potential bone infection, conducive nonunion delayed healing. Herein, we designed a adhesive with anti-infection, osteogenic adhesion properties promote fractures subsequent soft tissue repair. It was...

10.1016/j.bioactmat.2023.01.021 article EN cc-by-nc-nd Bioactive Materials 2023-02-09

Intraoperative-acquired pressure injuries (IAPIs) are a common complication in posterior intervertebral fusion surgery, leading to adverse outcomes for patients. However, there is lack of large-scale national database research analyzing the morbidity and associated risk factors IAPIs this surgical procedure. This retrospective study analyzed data from National Inpatient Sample (NIS) 2010 2019. Demographic, hospital, patient characteristics were examined, including length stay (LOS), total...

10.1016/j.jtv.2025.100873 article EN cc-by-nc-nd Journal of Tissue Viability 2025-03-06

P urpose . To investigate the value of SUV metrics and radiomic features based on ability 18 F-FDG PET/CT in differentiating between breast lymphoma carcinoma. Methods A total 67 nodules from 44 patients who underwent pretreatment were retrospectively analyzed. Radiomic parameters extracted using LIFEx package PET CT images. All texture divided into six groups: histogram (HISTO), SHAPE, gray-level co-occurrence matrix (GLCM), run-length (GLRLM), neighborhood different (NGLDM), zone-length...

10.1155/2019/4507694 article EN Contrast Media & Molecular Imaging 2019-02-25

Abstract Enhanced recovery after surgery (ERAS) has been shown to shorten length of hospital stay and reduce perioperative complications in many types surgeries. However, there a paucity research examining the application ERAS major spinal surgery. The current study was performed compare laminoplasty between an group traditional care group. included 114 patients who underwent managed with protocol January 2016 June 2017. 110 patients, received November 2014 December 2015. Postoperative...

10.1097/md.0000000000013195 article EN cc-by-nc Medicine 2018-11-01

Abstract Background Immune checkpoint inhibitor (ICI) therapy combined with conventional therapies is being broadly applied in non-small cell lung cancer (NSCLC) patients. However, the risk of interstitial pneumonitis (IP) following a regimen incompletely characterized. Methods A total 46,127 NSCLC patients were extracted for disproportionality analyses IP from Food and Drug Administration’s Adverse Event Reporting System (FAERS) database. 1108 who received ICI treatment at Nanfang Hospital...

10.1186/s12916-022-02713-6 article EN cc-by BMC Medicine 2023-01-05

Abstract Purpose The goal is to identify risk factors associated with receiving a blood transfusion during the perioperative period in patients who undergo total laparoscopic hysterectomy (TLH) using large-scale national database. Methods In this retrospective analysis, data from Nationwide Inpatient Sample (NIS) was utilized review medical records of all underwent TLH 2010 2019. researchers identified had received and compared those not. subsequent were examined: hospital characteristics...

10.1186/s12905-024-02908-4 article EN cc-by BMC Women s Health 2024-01-24

Background With the increasing number of patients with knee osteoarthritis undergoing TKAs in China, there is a clear need for valid, short, joint-specific patient-reported outcome measure such as Oxford Knee Score (OKS). Questions/purposes To test translated and cross-culturally adapted Chinese (Mandarin) version (OKS-CV) its (1) reliability, (2) construct validity, (3) dimensionality, (4) responsiveness. Methods Three native bilingual translators (a professional English translator, an...

10.1007/s11999-017-5495-2 article EN Clinical Orthopaedics and Related Research 2017-09-11

Abstract This study compared the radiologic and clinical outcomes of a new seven-axis robotic-assisted total hip arthroplasty (THA) conventional THA. Hundred four patients were randomly assigned to two groups—the THA group (RAS group) (CON group). The preoperative postoperative Harris Hip score (HHS), acetabular inclination, anteversion, femoral offset, leg length discrepancy (LLD) compared. During follow-up, no had any complications that could be associated with use robot. proportion cups...

10.1038/s41598-024-63624-5 article EN cc-by Scientific Reports 2024-06-02
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