A5028738245- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Osteoarthritis Treatment and Mechanisms
- Knee injuries and reconstruction techniques
- Hip disorders and treatments
- Blood transfusion and management
- Venous Thromboembolism Diagnosis and Management
- Bone and Joint Diseases
- Mesenchymal stem cell research
- Anesthesia and Pain Management
- Micro and Nano Robotics
- Simulation and Modeling Applications
- Shoulder Injury and Treatment
- Tendon Structure and Treatment
- MicroRNA in disease regulation
- Applied Advanced Technologies
- Inflammatory mediators and NSAID effects
- Cancer-related molecular mechanisms research
- Bone Tissue Engineering Materials
- Advanced Computational Techniques and Applications
- Ion-surface interactions and analysis
- Medical Research and Treatments
- E-commerce and Technology Innovations
- Cardiovascular Function and Risk Factors
Ministry of Education of the People's Republic of China
2012-2025
Peking University
2016-2025
Peking University Third Hospital
2016-2025
Chongqing University of Science and Technology
2024-2025
Southwest Medical University
2024
Shanghai Cell Therapy Research Institute
2024
First Affiliated Hospital of Sichuan Medical University
2024
Xiamen Medical College
2024
China Academy of Space Technology
2022
Hunan Police Academy
2022
Objective: A prospective, multicenter, randomized controlled trial was conducted to explore the short-term effect of a new robotic-assisted total knee arthroplasty (TKA) system, and clinical radiographic effectiveness between system conventional TKA were compared analyzed. Materials Methods: Overall, 144 patients randomly divided into two groups, wherein 72 underwent using robotic‑assisted TKA. The demographic data parameters collected. factors influencing postoperative hip–knee–ankle (HKA)...
The authors propose a framework to deal with unsupervised machine learning of both topological phases and non-topological ones. From this, the Calinski-Harabaz index score can be used probe phase transitions.
ABSTRACT Objective With the global aging population, incidence of OA is rising annually, and number TKA surgeries rapidly increasing, placing a heavy economic healthcare burden on society. As one key medications in ERAS protocol, DXM can significantly reduce postoperative pain, suppress nausea vomiting, accelerate patient recovery. However, safety perioperative use patients with diabetes remains unclear. This study aims to clarify application diabetic patients. Methods retrospective analysis...
Purpose In recent years, the incidence of cardiovascular disease has continued to rise, and early screening prevention are especially critical. Phonocardiography (PCG) electrocardiography (ECG), as simple, cost-effective non-invasive tests, important tools for clinical analysis. However, it is difficult fully reflect complexity system using PCG or ECG tests alone. Combining multimodal signals can provide complementary information improve detection accuracy. Therefore, purpose this paper...
Abstract Anteromedial osteoarthritis (AMOA) is characterized by progressive and irreversible cartilage damage in anteromedial knee joint, targeted therapies for it are lacking. To address this challenge, a magnetically controlled drug‐loaded microrobot developed based on Chlorella incorporated quercetin, named M‐CH@QUE, which designed precise drug delivery targeting AMOA. M‐CH@QUE not only alleviated OA symptoms but also protected the slowed progression of In vitro experiments demonstrated...
Background: The overall satisfaction of patients after total knee arthroplasty (TKA) is approximately 80%, and current studies have demonstrated that with depression may lower patient satisfaction. purpose this study was to determine whether perioperative psychological intervention in improves the clinical outcomes undergoing TKA. Methods: Six hundred who underwent primary TKA from May 2016 January 2018 were prospectively screened for eligibility. A preoperative evaluation conducted by a...
Abstract The use of natural cartilage extracellular matrix (ECM) has gained widespread attention in the field tissue engineering. However, current approaches for delivering functional scaffolds osteoarthritis (OA) therapy rely on knee surgery, which is limited by narrow and complex structure articular cavity carries risk injuring surrounding tissues. This work introduces a novel cell microcarrier, magnetized ECM‐derived (M‐CEDSs), are derived from decellularized porcine ECM. Human bone...
Osteonecrosis of the femoral head, an intractable but common disease that eventually triggers collapse is characterized by increased osteoclast activity and markedly decreased osteoblast in necrotic region head. MicroRNA (miRNA)-214 (miR-214) may play important roles vertebrate skeletal development inhibiting function targeting activating transcription factor 4 (ATF4) promoting via phosphatase tensin homolog (PTEN). This study revealed significantly levels miR-214 regions, with commensurate...
Abstract Background Aseptic cup loosening is still one of the main reasons leading to acetabular failures. 3D printing porous trabecular titanium metal may provide good initial stability and secondary fixation because its highly interconnected, structure. Few large sample studies have reported clinical outcomes electron beam melting (EBM) in Chinese population. Methods We retrospectively collected analyzed data a total 92 consecutive patients between January 2013 November 2017, with an...
Objective The different cutting mode of robot‐assisted TKAs may influence the accuracy alignment. purpose this study was to compare alignment and early clinical outcomes between a CT‐based, saw robotic system (MAKO) CT‐free, jig‐guided (ROSA) for total knee arthroplasty (TKA). Methods A 20 MAKO ROSA from June 2021 2022 were retrospectively analyzed. Differences in postoperative hip‐knee‐ankle (HKA) angle, lateral distal femoral angle (LDFA), medial proximal tibial (MPTA), posterior slope...
Intraoperative proximal femoral fracture, one of the most common complications total hip arthroplasty (THA), occurs more often in cementless procedures and can affect rehabilitation, hospitalization time, cost treatment. The goal this study was to identify risk factors for intraoperative fracture THA high-risk groups preoperatively minimize incidence complication. This nested case-control included 904 primary (769 patients) performed between January 2009 July 2015. Of group, 24 fractures...
As the first diagnostic imaging modality of avascular necrosis femoral head (AVNFH), accurately staging AVNFH from a plain radiograph is critical yet challenging for orthopedists. Thus, we propose deep learning-based diagnosis system (AVN-net). The proposed AVN-net reads radiographs pelvis, conducts diagnosis, and visualizes results automatically. Deep convolutional neural networks are trained to provide an end-to-end solution, covering tasks detection, exam-view identification, side...
Microrobots with simultaneously improved degradability and mechanical strength are highly demanded in performing vivo delivery tasks clinical applications. The properties of contradictory for many materials used to make microrobots. This article proposes a new design that can result 3D cell culture microrobots from the following perspectives. First, microrobot is using triangle patterns replace hexagon pattern structure, which provide more supporting grids obtain increased strength. Second,...
To review the clinical outcomes of revision total knee arthroplasty (RTKA) with massive proximal tibial bone defects using patient-customized three-dimensional (3D) printed highly porous metaphyseal cones. A retrospective study all patients at our institution who underwent RTKA Anderson Orthopaedic Research Institute type III 3D-printed cones was performed from 2016 to 2018. Seven were enrolled in this study. General results (age, sex, and body mass index); intraoperative (interface...
Deep vein thrombosis (DVT) is a common postoperative complication of knee/hip arthroplasty. There continued need for artificial intelligence-based methods predicting lower extremity DVT risk after In this study, we performed retrospective study to analyse the data from patients who underwent primary arthroplasty between January 2017 and December 2021 with bilateral venous ultrasonography. Patients' features were extracted electronic health records (EHRs) assigned training (80%) test (20%)...
ITFG2, as an immune-modulatory intracellular protein that modulate the fate of B cells and negatively regulates mTORC1 signaling. ITFG2 is highly expressed in heart, but its pathophysiological function heart disease unclear. In this study, we found MI mice, overexpression via AAV9 vector significantly reduced infarct size ameliorated cardiac function. Knockdown endogenous by shRNA partially aggravated ischemia-induced dysfunction. cardiac-specific transgenic (TG) myocardial infarction was...