A5084760342- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Antibiotic Resistance in Bacteria
- SARS-CoV-2 and COVID-19 Research
- Plant Pathogens and Fungal Diseases
- COVID-19 Clinical Research Studies
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- COVID-19 and healthcare impacts
- Antibiotic Use and Resistance
- SARS-CoV-2 detection and testing
- Antibiotics Pharmacokinetics and Efficacy
- Infectious Diseases and Mycology
- Nail Diseases and Treatments
- Pneumonia and Respiratory Infections
- Mycotoxins in Agriculture and Food
- COVID-19 epidemiological studies
- Neutropenia and Cancer Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- Bacterial biofilms and quorum sensing
- Mycobacterium research and diagnosis
- Viral gastroenteritis research and epidemiology
- Fungal Plant Pathogen Control
- Streptococcal Infections and Treatments
- Cystic Fibrosis Research Advances
Ospedaliera di Piacenza
2021-2025
University of Parma
2024-2025
Italian Association for Cancer Research
1994-2024
Azienda Unità Sanitaria Locale Piacenza
2021-2024
Guglielmo da Saliceto Hospital
2021-2023
Azienda Ospedaliera Universitaria Integrata Verona
2013-2022
University of Verona
2001-2021
Università Cattolica del Sacro Cuore
1997-2004
University of Turin
2004
Azienda Ospedaliera San Camillo-Forlanini
2004
Nine of 11 hematological patients with disseminated/deep-seated Fusarium infection tested at least twice for Aspergillus galactomannan (GM) had repeated positive results in the absence isolation culture. The centrifuged supernatants 12 isolates were by a GM enzyme-linked immunosorbent assay (EIA). All produced reactions when undiluted. These show cross-reactivity spp. that may constitute drawback respect to specificity Platelia EIA.
Article Assessment of immune response to SARS-CoV-2 with fully automated MAGLUMI 2019-nCoV IgG and IgM chemiluminescence immunoassays was published on July 1, 2020 in the journal Clinical Chemistry Laboratory Medicine (CCLM) (volume 58, issue 7).
Abstract Objectives When bloodstream infections are caused by resistant bacteria, rapid antimicrobial susceptibility testing (RAST) is important for adjustment of therapy. The EUCAST RAST method, directly from positive blood cultures, was validated in a multi-laboratory study Europe. Methods performed 40 laboratories northern Europe (NE) and 15 southern (SE) clinical cultures Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus or Streptococcus pneumoniae....
Abstract Objectives The ongoing outbreak of coronavirus disease (COVID-19) caused by the severe acute respiratory syndrome 2 (SARS-CoV-2) poses formidable challenges to all health care systems. Serological assays may be used for improving management when appropriately applied, investigating antibody responses mounted against SARS-CoV-2 infection and assessing its real prevalence. Although testing whole population is impractical, well-designed serosurveys in selected subpopulations specific...
Objectives: Invasive mold infections associated with Aspergillus species are a significant cause of mortality in immunocompromised patients. The most frequently occurring aetiological pathogens members the section Fumigati followed by Terrei. frequency terreus and related (cryptic) clinical specimens, as well percentage azole-resistant strains remains to be studied. Methods: A global set (n = 498) A. phenotypically isolates was molecularly identified (beta-tubulin), tested for antifungal...
Patients with cancer are presumed a frail group at high risk of contracting coronavirus disease (COVID-19), and vaccination represents cornerstone in addressing the COVID-19 pandemic. However, data on patients fragmentary poor.An observational study was conducted to evaluate seropositivity rate safety two-dose regimen BNT162b2 or messenger RNA-1273 vaccine adult solid undergoing active anticancer treatment whose had been terminated within 6 months start study. The control composed healthy...
We compared the risk factors, diagnostic tools and outcome of filamentous fungal infections (FFIs) in hematological patients (HAEs) non-hematological (non-HAEs).Prospective surveillance (2009-2011) proven probable FFIs was implemented 23 Italian hospitals.Out 232 FFIs, 113 occurred HAEs 119 non-HAEs. The most frequent infection invasive aspergillosis (76.1 % for HAEs, 56.3 non-HAEs), localization principally pulmonary (83.2 74.8 non-HAEs). Neutropenia a factor 89.4 HAEs; main underlying...
•In SARS-CoV-2-naïve subjects, spike-specific T-cell response was significantly increased after the second dose of vaccine•In patients treated with chemo-immunotherapy, seems to be lower borderline statistical significance•Between naïve and experienced patients, no differences were reported in terms CD4- CD8-specific response•In level SARS-CoV-2 neutralizing antibodies reached a higher median 1 : 80 dose•No COVID-19 cases documented throughout period study BackgroundVery few cancer enrolled...
•All subjects but one reached detectable IgG levels 3 weeks after the third dose of SARS-CoV-2 BNT162b2 messenger RNA vaccine.•A median 16-fold increase NT Ab titer was observed in patients without previous COVID-19.•The cell-mediated immune response significantly higher SARS-CoV-2-naïve booster.•Median level Abs 32-fold lower against Omicron compared to wild-type strain. BackgroundAlthough a full course coronavirus disease 2019 (COVID-19) vaccine is effective cancer patients, duration...
A single primer pair amplifying a cytochrome P-450 lanosterol-14 alpha-demethylase (L1A1) gene fragment that encodes highly conserved region was used to detect yeast DNA in clinical specimens. Positive PCR products were obtained from genomic DNAs of Candida albicans, C. parapsilosis, tropicalis, guilliermondii, krusei, (Torulopsis) glabrata, and kefyr. No human, bacterial, or parasitic amplified. The sensitivity evaluated for albicans by using various concentrations (200 pg 2 fg). amplified...
A survey of antimicrobial resistance in Streptococcus pyogenes, performed within the framework a national surveillance program, has revealed dramatic increase S. pyogenes to erythromycin most areas Italy. In virtually all centers that provided data for 3 consecutive years, incidence erythromycin-resistant strains increased twofold 20-fold from 1993 1995 and was greater than 30% five 14 participating study. The clonality isolates studied 15 isolated different patients at Institute...
Fungemia is a co-infection contributing to the worsening of critically ill COVID-19 patient. The multicenter Italian observational study FiCoV aims estimate frequency yeast bloodstream infections (BSIs), describe factors associated with BSIs in patients hospitalized 10 hospitals, and analyze antifungal susceptibility profiles yeasts isolated from blood cultures. included all adult BSI; anonymous data was collected each patient about collected. Yeast BSI occurred 1.06% patients, 0.14% 3.39%...
ABSTRACT We report on the cloning and sequencing of vanA gene cluster present in glycopeptide-resistant clinical isolate Bacillus circulans VR0709 (R. Fontana, M. Ligozzi, C. Pedrotti, E. Padovani, G. Cornaglia, Eur. J. Clin. Microbiol. Infect. Dis. 16:473–474, 1997). The presence a -related was demonstrated PCR assay which permitted specific amplification an internal segment . Southern blotting suggested that located chromosome 7.6-kb Eco RI fragment. DNA sequence analysis revealed all...
Italy presented the first largest COVID-19 outbreak outside of China. Veneto currently ranks fourth among Italian regions for confirmed cases (~19,000). This study presents health surveillance data SARS-CoV-2 in 6100 workers (HW) employed a large public hospital. Workers underwent oropharyngeal and nasopharyngeal swabs, with total 5942 participants (97.5% population). A 11,890 specimens were tested infection using PCR, identifying viral genes E, RdRP, N. Positive tests returned 238...
New fungal species are increasingly reported in immunocompromised patients. Saprochaete clavata (S. clavata), an ascomycetous fungus formerly called Geotrichum clavatum, is intrinsically resistant to echinocandins and often misidentified.We describe a cluster of seven S. infections hospitalized hematology patients who developed this rare fungemia within span 11 months. Three the died. Identification isolates was determined only with Saramis database VitekMS system sequencing internal...