Quanhua Zhou
A5088405456- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- HIV-related health complications and treatments
Czech Academy of Sciences, Institute of Microbiology
2024
HIV subtypes convey important epidemiological information and possibly influence the rate of disease progression. In this study, progression in patients infected with CRF01_AE, CRF07_BC, subtype B was compared largest molecular epidemiology study ever done China. A national data set pol sequences assembled by pooling from public databases Beijing laboratory network. Logistic regression used to assess factors associated risk AIDS at diagnosis ([AIDSAD], defined as a CD4 count < 200 cells/µL)...
Abstract Background National treatment guidelines of China evolving necessitates population-level surveillance transmitted drug resistance (TDR) to inform or update HIV strategies. Methods We analyzed the demographic, clinical, and virologic data obtained from people with (PWH) residing in 31 provinces who were newly diagnosed between 2018 2023. Evidence TDR was defined by World Health Organization list for mutations. Results Among 22 124 PWH protease reverse transcriptase sequences, 965...
Abstract Background In 2016, China has implemented the World Health Organization's “treat all” policy. We aimed to assess impact of significant improvements in 95-95-95 targets on population-level human immunodeficiency virus (HIV) transmission dynamics and incidence. Methods focused 3 steps HIV care continuum: diagnosed, antiretroviral therapy, achieving viral suppression. The molecular clusters were inferred using HIV-TRACE. New infections estimated incidence method European Centre for...
Background: HIV subtypes convey important epidemiological information and possibly influence the rate of disease progression. Data on effect strains CRF01_AE CRF07_BC progression are limited, national subtype distribution trends needs to be updated. In this study, in patients infected with CRF01_AE, CRF07_BC, B was compared largest molecular epidemiology study ever done China.Methods: A data set pol sequences assembled by pooling from public databases Beijing laboratory network (BHLN). The...