Tingyu Zhang

ORCID: 0000-0003-4469-4035
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Research Areas
  • Cardiovascular Function and Risk Factors
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Lipoproteins and Cardiovascular Health
  • Acute Myocardial Infarction Research
  • Viral Infections and Vectors
  • Cancer, Lipids, and Metabolism
  • Viral Infections and Outbreaks Research
  • Cardiac Imaging and Diagnostics
  • SARS-CoV-2 detection and testing
  • Coronary Interventions and Diagnostics
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Inflammatory Biomarkers in Disease Prognosis
  • Metabolism, Diabetes, and Cancer
  • Atherosclerosis and Cardiovascular Diseases
  • Cancer-related molecular mechanisms research
  • Hepatitis B Virus Studies
  • Global Public Health Policies and Epidemiology
  • Obesity, Physical Activity, Diet
  • Smoking Behavior and Cessation
  • Nutrition and Health in Aging
  • Liver physiology and pathology
  • Sulfur Compounds in Biology
  • Nutritional Studies and Diet
  • Fire effects on ecosystems

The First Hospital of Kunming
2025

Capital Medical University
2018-2025

Beijing Ditan Hospital
2021-2025

Ruijin Hospital
2025

Shanghai Jiao Tong University
2025

Anhui Medical University
2022-2024

Ludwig-Maximilians-Universität München
2024

Heilongjiang University of Chinese Medicine
2023

Anhui Polytechnic University
2023

Hebei GEO University
2022

Abstract Background The relationship between triglyceride-glucose index (TyG index) and the prevalence prognosis of cardiovascular disease has been confirmed by former studies. However, it remains uncertain whether TyG a prognostic impact in patients with type 2 diabetes mellitus (T2DM) non-ST-segment elevation acute coronary syndrome (NSTE-ACS) undergoing percutaneous intervention (PCI). Methods study retrospectively enrolled 798 (mean age: 60.9 ± 8.3 years; 68.3% men) T2DM NSTE-ACS who...

10.1186/s12933-020-01086-5 article EN cc-by Cardiovascular Diabetology 2020-07-08

The triglyceride-glucose index (TyG index) is proposed as a surrogate parameter for insulin resistance (IR) and, when elevated, related to increased cardiovascular risks. Whether the TyG of great value in predicting adverse prognosis individuals diagnosed with non-ST-segment elevation acute coronary syndrome (NSTE-ACS), who received elective percutaneous intervention (PCI), and without recognized diabetes remains unclear.

10.5551/jat.59840 article EN Journal of Atherosclerosis and Thrombosis 2020-11-12

Persulfate, a powerful oxidizing agent, is extensively employed in numerous industries.

10.1039/d4ra08915d article EN cc-by-nc RSC Advances 2025-01-01

ABSTRACT Geriatric nutritional risk index (GNRI) has been proposed as a reliable indicator of state and, when decreased, is closely associated with the severity and mortality infectious disease. The current study retrospectively recruited patients who were admitted for SFTS from January 1, 2011 to 2024 at six medical centers. Two hundred eighty‐two met protocol finally enrolled in this study. Sixty suffered in‐hospital death during hospitalization, rate 21.3%. After adjustment multiple...

10.1002/jmv.70252 article EN cc-by Journal of Medical Virology 2025-02-01

Glycated hemoglobin (HbA1c) is widely used to assess long-term glycemic control in individuals with diabetes. However, various conditions that affect levels or the lifespan of red blood cells can compromise accuracy HbA1c measurements. Despite extensive research, relationship between and remains unclear. This study aims clarify this by examining its correlation across diverse age gender cohorts. Data from 217,991 participants aged 20 69 years were collected health examination centers...

10.1111/1753-0407.70057 article EN cc-by Journal of Diabetes 2025-02-01

Diabetes mellitus, and even prediabetes, has been shown to be independently associated with cardiovascular disease. Our study explored whether the combination of glycosylated hemoglobin (HbA 1c ) fasting blood glucose (FBG) can better assess severity coronary heart disease (CHD) in elective percutaneous intervention (PCI) patients. We consecutively enrolled 1006 prediabetic patients HbA 5.7% 6.4% who underwent PCI. Patients were divided into 2 groups: a normal (NFG) group (FBG <6.1...

10.1177/0003319719887655 article EN Angiology 2019-11-21

The importance of monocyte/lymphocyte ratio (MLR) has been indicated in the initiation and progression coronary artery disease. However, few previous researches demonstrated relationship between MLR plaque vulnerability. We aimed to investigate non-culprit vulnerability patients with acute syndrome (ACS) by optical coherence tomography (OCT).A total 72 ACS who underwent angiography OCT test Beijing Anzhen Hospital were included this retrospective study. morphology assessed OCT.The high group...

10.1097/md.0000000000021562 article EN cc-by-nc Medicine 2020-10-06

Abstract Background It is uncertain whether estimated remnant-like particle cholesterol (RLP-C) could predict residual risk in patients with different glycometabolic status. This study aimed to evaluate the relationship between RLP-C and adverse prognosis non-ST-segment elevation acute coronary syndrome (NSTE-ACS) treated percutaneous intervention (PCI) identify potential impact of glycometabolism on predictive value RLP-C. Methods The assessed 2419 participants NSTE-ACS undergoing PCI at...

10.1186/s12944-020-01355-y article EN cc-by Lipids in Health and Disease 2020-07-31

The SARS-CoV-2 B.1.1.7 variant has increased sharply in numbers worldwide and is reported to be more contagious than the nonvariant. Little known regarding detailed clinical features of infection. Data on 74 COVID-19 cases from two outbreaks districts Beijing, China were extracted a cloud database, including 41 Shunyi District (Shunyi B.1.470 group) 33 Daxing (Daxing December 25, 2020 January 17, 2021. We conducted comparison characteristics. Seven indicators group significantly higher those...

10.1128/spectrum.00273-21 article EN cc-by Microbiology Spectrum 2021-08-04

Background: The research on the association between relative glycemic level postpercutaneous coronary intervention (PCI) and adverse prognosis in non-ST-segment elevation acute syndrome (NSTE-ACS) patients is relatively inadequate. Objective: study aimed to identify whether post-PCI predicts NSTE-ACS patients. Methods: Patients (n=2465) admitted with who underwent PCI were enrolled. post-procedure was calculated as blood glucose divided by HbA1c level, which named post-procedural index...

10.2174/1570161118666200317145540 article EN Current Vascular Pharmacology 2020-03-17

Background: Triglyceride-glucose (TyG) index has been proposed as a reliable indicator for insulin resistance and proved to be closely associated with the severity mortality risk of infectious diseases. It remains indistinct whether TyG performs an important role in predicting in-hospital patients severe fever thrombocytopenia syndrome (SFTS). Methods: The current study retrospectively recruited who were admitted SFTS from January December 2019 at five medical centers. was calculated...

10.3389/fmed.2021.768101 article EN cc-by Frontiers in Medicine 2022-01-04

Chronic HBV infection is a significant public health problem and one major cause of liver cirrhosis hepatocellular carcinoma (HCC). impairs the host immune system results in immunotolerance, which obstacle to therapy. CpG oligodeoxynucleotide (ODN) strong immunostimulant activates innate response rapidly has been shown be an efficient therapy agent viral treatment. Here, we report anti-HBV activity CpG-1826 hydrodynamic injection murine model.CpG-1826 was administrated intraperitoneally...

10.3851/imp2870 article EN Antiviral Therapy 2014-04-01

To evaluate the prevalence and predictors of smoking relapse after percutaneous coronary intervention in Chinese patients.Smoking is considered a vital risk factor for heart disease. Although cessation could decrease risks adverse cardiac outcomes, many patients resume following short period abstinence. However, little known about resumption who have undergone intervention.A longitudinal study was conducted among underwent intervention. Predictive variables were assessed at baseline through...

10.1111/jocn.14050 article EN Journal of Clinical Nursing 2017-08-23

Severe fever with thrombocytopenia virus (SFTSV), an emerging tick-borne bandavirus, poses a significant public health threat in rural China. Since 2021, increase local cases has been noted the rural-urban fringe surrounding Beijing. This study aimed to assess formation of natural foci urban areas by conducting field survey ticks and hedgehogs from Beijing's second fifth ring roads. Our revealed diverse tick population city parks, including major SFTSV vector, H. longicornis. Parthenogenetic...

10.1101/2024.02.18.580844 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-02-18

<h3>Introduction/Background</h3> Translational approaches with appropriate experimental models are required to understand the mechanisms of platinum resistance in highly variable disease high-grade serous ovarian cancer (HGSOC). Our biobank a cohort more than 200 patient-derived HGSOC organoids (PDOs) enables functional study patient-specific responses and PDO long-term expansion potential after vitro carboplatin exposure by our developed Organoid Forming Efficiency (OFE) Test....

10.1136/ijgc-2024-esgo.557 article EN 2024-03-01

The predictive value of the methylation Long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) and H19 promoters in peripheral blood leukocytes as a non-invasive biomarker for chemotherapy effect prognosis gastric cancer (GC) is unclear. DNA MALAT1 between chemotherapy-sensitive non-sensitive groups with better worse survival GC was compared using regression analyses. Several nomograms were constructed. genetic alteration association gene expression...

10.1016/j.tranon.2024.101929 article EN cc-by-nc Translational Oncology 2024-03-16

Severe fever with thrombocytopenia virus (SFTSV), an emerging tick-borne bandavirus, poses a significant public health threat in rural China. Since 2021, increase of local cases has been noted the rural-urban fringe Beijing. This study aimed to assess formation natural foci urban areas by conducting field survey ticks and hedgehogs from second fifth ring roads Our revealed diverse tick population city parks, including major SFTSV vector, Haemaphysalis longicornis. Parthenogenetic H....

10.1016/j.virs.2024.11.002 article EN cc-by-nc-nd Virologica Sinica 2024-11-01

The Super-SBM model was used first to assess the energy efficiency of 30 Chinese provinces from 2012 2017. After that, an spatial correlation test conducted, and finally, influencing elements were analyzed using a geographic panel model. findings show that amount regional economic development has substantial positive impact on efficiency, whereas level urbanization severity environmental restrictions have considerable negative in China’s provinces. Other regions’ structure technical...

10.46488/nept.2022.v21i02.012 article EN cc-by Nature Environment and Pollution Technology 2022-06-01

Summary Background The SARS-CoV-2 B.1.1.7 variant which was first identified in the United Kingdom (U.K.) has increased sharply numbers worldwide and reported to be more contagious. On January 17, 2021, a COVID-19 clustered outbreak caused by occurred community Daxing District, Beijing, China. Three weeks prior, another non-variant (lineage B.1.470) Shunyi Beijing. This study aimed investigate clinical features of infection. Methods A prospective cohort conducted on cases admitted Ditan...

10.1101/2021.05.04.21256655 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-05-08
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