A5103137374- Bone health and osteoporosis research
- Radiomics and Machine Learning in Medical Imaging
- Bone and Joint Diseases
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Advanced X-ray and CT Imaging
- Medical Imaging and Analysis
- Bone Metabolism and Diseases
- Cardiac Imaging and Diagnostics
- Colorectal Cancer Surgical Treatments
- Advanced Neuroimaging Techniques and Applications
- Bone health and treatments
- Photoacoustic and Ultrasonic Imaging
- Endometrial and Cervical Cancer Treatments
- Sarcoma Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Acute Ischemic Stroke Management
- COVID-19 Clinical Research Studies
- Lanthanide and Transition Metal Complexes
- Cerebrovascular and Carotid Artery Diseases
- Nanoplatforms for cancer theranostics
- Atomic and Subatomic Physics Research
- Gastrointestinal Tumor Research and Treatment
- Nutrition and Health in Aging
- Gastrointestinal motility and disorders
Shanghai Tenth People's Hospital
2015-2024
Tongji University
2015-2024
Nanjing Medical University
2020-2024
Shanghai Stomatological Hospital
2024
Fudan University
2024
Northern Jiangsu People's Hospital
2024
Shanghai East Hospital
2013
First Affiliated Hospital of Jiangxi Medical College
2011
Creative Research Enterprises (United States)
2011
Shanghai Jiao Tong University
2009
Abstract Personalized radiotherapy strategies enabled by the construction of hypoxia‐guided biological target volumes (BTVs) can overcome hypoxia‐induced radioresistance delivering high‐dose to targeted hypoxic areas tumor. However, BTVs is difficult owing lack precise visualization areas. This study synthesizes a hypoxia‐responsive T 1 , 2 mapping tri‐modal MRI molecular nanoprobe (SPION@ND) and provides imaging tumor utilizing advantageous features magnetic resonance (MRI). SPION@ND...
We report the synthesis of poly(N-vinylcaprolactam) nanogels (PVCL NGs) loaded with gadolinium (Gd) for tumor MR imaging applications. The PVCL NGs were synthesized via precipitation polymerization using monomer N-vinylcaprolactam (VCL), comonomer acrylic acid (AAc), and degradable cross-linker 3,9-divinyl-2,4,8,10-tetraoxaspiro-[5,5]-undecane (VOU) in aqueous solution, followed by covalently binding...
We evaluated the diagnostic efficacy of deep learning radiomics (DLR) and hand-crafted (HCR) features in differentiating acute chronic vertebral compression fractures (VCFs).A total 365 patients with VCFs were retrospectively analysed based on their computed tomography (CT) scan data. All completed MRI examination within 2 weeks. There 315 205 VCFs. Deep transfer (DTL) HCR extracted from CT images using DLR traditional radiomics, respectively, feature fusion was performed to establish least...
To synthesize and characterize cost-efficient polyethylenimine-entrapped gold nanoparticles loaded with gadolinium (Gd@Au PENPs) for dual-mode computed tomography (CT)/magnetic resonance (MR) imaging applications.PEGylated PEI modified (Gd) chelator (DOTA) was used as a template to the Gd@Au PENPs particles were well characterized in terms of their physicochemical properties, cytotoxicity performances CT MR vitro vivo.The formed low can be highly efficient contrast agent CT/MR blood pool...
Purpose To investigate the effect of stretching sampling window on quantitative 3D ultrashort TE (UTE) imaging cortical bone at 3 T. Methods Ten bovine and 17 human tibial midshaft samples were imaged with a 3T clinical MRI scanner using an 8‐channel knee coil. Quantitative UTE biomarkers, including T 1 , magnetization transfer ratio modeling, performed radial or spiral Cones trajectories various durations. Errors in UTE‐MRI biomarkers as function time evaluated reference standard. Results...
Head and neck (HN) rhabdomyosarcoma (RMS) is an aggressive malignancy, which rarely encountered commonly misdiagnosed as another type of tumor. The aim the present study was to investigate computed tomography (CT) magnetic resonance imaging (MRI) features HNRMS analyze correlations between observations pathological subtypes. A total 10 patients (three males seven females; median age, 16 years) were reviewed retrospectively by only CT (n=1), MRI (n=2), well (n=7). In addition, clinical data,...
Osteoporosis is a bone‑related disease that results from impaired bone formation and excessive resorption. The potential value of adipokines has been investigated previously, due to their influence on osteogenesis. However, the osteogenic effects induced by omentin‑1 remain unclear. aim present study was determine regulatory osteoblast viability differentiation, as well explore underlying molecular mechanism. differentiation mouse pre‑osteoblast cells (MC3T3‑E1) using quantitative...
To investigate the diagnostic efficacy of mDIXON-Quant technique for prediction bone loss in male adults.One hundred thirty-eight adults were divided into normal, osteopenia, and osteoporosis groups based on DXA QCT lumbar spine. Differences parameters [fat fraction (FF) T2* value] among three groups, as well correlation mineral density (BMD) analyzed. The areas under curves (AUCs) low mass calculated.According to standard, FF value significantly increased group compared with normal (P =...
Abstract: Macrophages are becoming increasingly significant in the progression of atherosclerosis (AS). Molecular imaging macrophages may improve detection and characterization AS. In this study, dendrimer-entrapped gold nanoparticles (Au DENPs) with polyethylene glycol (PEG) fluorescein isothiocyanate (FI) coatings were designed, tested, applied as contrast agents for enhanced computed tomography (CT) atherosclerotic lesions. Cell counting kit-8 assay, fluorescence microscopy, silver...
Purpose To determine the longitudinal relationships among lumbar vertebral blood perfusion, bone mass, and marrow adipose tissue in a rat osteoporosis model after ovariectomy by using quantitative dynamic contrast agent-enhanced (DCE) magnetic resonance (MR) imaging, microcomputed tomography (micro-CT), proton MR spectroscopy. Materials Methods In this animal review committee-approved study, vertebrae were evaluated through spectroscopy, DCE micro-CT, histopathologic analysis, was examined...
A recent cluster of pneumonia cases in Wuhan (China) is known to be caused by a novel beta-coronavirus named the corona virus disease 2019 (COVID-19) and can spread through human-to-human transmission.Data 21 patients with laboratory-confirmed COVID-19 84 suspected were analyzed RT-PCR. The epidemiologic clinical features as well outcomes compared between confirmed cases.Altogether 105 had been enrolled this study February 15, 2020 north Shanghai, including COVID-19. incubation period these...
The purpose of this article is to compare the efficacy self-expanding metallic stents and pneumatic dilation for long-term clinical treatment achalasia.Patients diagnosed with achalasia (n = 120) were allocated 30; group A) or a temporary stent diameter 20 mm B), 25 C), 30 D). Data on symptoms, complications, outcomes collected, follow-up was performed at 6 months 1, 3-5, 5-8, 8-10, more than 10 years after surgery.Pneumatic placement technically successful in all patients. revealed that...
PURPOSE:To evaluate the efficacy of added shear wave elastography (SWE) in breast screening for women with results inconsistent between mammography and conventional ultrasounds (US). MATERIALS AND METHODS:The study consisted 282 pathologically proven lesions. The cancer probability from s creening by US were scored using Breast Imaging Reporting Data System (BI-RADS). Elastography was used to re-evaluate results. diagnostic performance US, mammography, Combined clinical imaging SWE compared....