Niek Verweij
- Genetic Associations and Epidemiology
- Metabolomics and Mass Spectrometry Studies
- Cardiac electrophysiology and arrhythmias
- Nutrition, Genetics, and Disease
- Epigenetics and DNA Methylation
- Genetic Mapping and Diversity in Plants and Animals
- Birth, Development, and Health
- Liver Disease Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Genetic and phenotypic traits in livestock
- Cardiomyopathy and Myosin Studies
- Heart Rate Variability and Autonomic Control
- Atrial Fibrillation Management and Outcomes
- Hemoglobinopathies and Related Disorders
- RNA modifications and cancer
- Lipoproteins and Cardiovascular Health
- Adipose Tissue and Metabolism
- Lipid metabolism and disorders
- Genetics and Neurodevelopmental Disorders
- Iron Metabolism and Disorders
- Cancer-related molecular mechanisms research
- Genomics and Rare Diseases
- Pancreatic function and diabetes
- Congenital heart defects research
- Folate and B Vitamins Research
University Medical Center Groningen
2016-2025
University of Groningen
2016-2025
Regeneron (United States)
2020-2025
Genomics (United Kingdom)
2019-2021
Medisch Centrum Leeuwarden
2021
Broad Institute
2016-2020
University Medical Center
2020
Dialyse Centrum Groningen
2019
Universidade Federal de Minas Gerais
2019
Queen Mary University of London
2013-2019
Genetic and lifestyle factors both contribute to the risk of developing cardiovascular disease, but whether poor health behaviors are associated with similar increases in among individuals low, intermediate, or high genetic is unknown.To investigate association combined within groups coronary artery atrial fibrillation, stroke, hypertension, type 2 diabetes as well interactions between lifestyle.The UK Biobank cohort study includes more than 500 000 participants aged 40 70 years who were...
Statin treatment and variants in the gene encoding HMG-CoA reductase are associated with reductions both concentration of LDL cholesterol risk coronary heart disease, but also modest hyperglycaemia, increased bodyweight, modestly type 2 diabetes, which no way offsets their substantial benefits. We sought to investigate associations cholesterol-lowering PCSK9 diabetes related biomarkers gauge likely effects inhibitors on risk.In this mendelian randomisation study, we used data from cohort...
How genes affect human obesity Obesity is linked to many diseases, including diabetes, cancer, and heart disease. There thus great interest in understanding how predispose individuals to, or protect from, obesity. Akbari et al. sequenced more than 600,000 exomes from the United Kingdom, States, Mexico identified 16 rare coding variants (see Perspective by Yeo O'Rahilly). Some of alleles associated with body mass index (BMI) were brain-expressed G protein–coupled receptors. One variant allele...