A5040418695- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Pneumonia and Respiratory Infections
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Nosocomial Infections in ICU
- Bacterial Identification and Susceptibility Testing
- Antibiotics Pharmacokinetics and Efficacy
- Long-Term Effects of COVID-19
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- COVID-19 diagnosis using AI
- Antifungal resistance and susceptibility
- Antimicrobial Resistance in Staphylococcus
- Respiratory Support and Mechanisms
- Hepatitis B Virus Studies
- Respiratory viral infections research
- Salmonella and Campylobacter epidemiology
- Clinical Laboratory Practices and Quality Control
- Pharmaceutical and Antibiotic Environmental Impacts
- Trypanosoma species research and implications
- Urinary Tract Infections Management
- Streptococcal Infections and Treatments
- Neonatal and Maternal Infections
Hospital Universitari Joan XXIII de Tarragona
2019-2025
Institut d'Investigació Sanitària Pere Virgili
2012-2023
Hospital Universitari Sant Joan de Reus
2020
Hospital de Tortosa Verge de la Cinta
2011-2017
Pseudomonas aeruginosa healthcare-associated infections are one of the top antimicrobial resistance threats world-wide. In order to analyze current trends, we performed a Spanish nation-wide high-resolution analysis susceptibility profiles, genomic epidemiology and resistome P. over five-year time lapse.A total 3.180 nonduplicated clinical isolates from two surveys in October 2017 2022 were analyzed. MICs 13 antipseudomonals determined by ISO-EUCAST. Multidrug (MDR)/extensively drug...
The aim of our study was to analyse the short-term prognostic value different biomarkers in patients with COVID-19.
Background/Objectives: Ventilator-associated pneumonia (VAP) is the main nosocomial infection in intensive care units (ICUs) that causes highest morbidity and mortality. The aim of our study to investigate variations crude ICU mortality among patients with VAP over past decade. We also wish identify associated risk factors, evaluate changes etiology, assess incidence impact inappropriate empirical antibiotic treatment (IEAT). Methods: conducted a retrospective, observational, single-center...
Treatment failure occurs in about 25% of patients with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia. We assessed whether cloxacillin plus fosfomycin achieves better treatment success than alone hospitalized adults MSSA conducted a multicenter, open-label, phase III-IV superiority randomized clinical trial. randomly assigned (1:1) to receive 2 g intravenous every 4 h or 3 6 for the initial 7 days. The primary endpoint was at day 7, composite following criteria: patient...
Current evidence is inconclusive regarding the intrapartum administration of chemoprophylaxis, merely based on presence group B streptococcal (GBS) bacteriuria any colony count, in prevention early-onset neonatal GBS infection. The aim this study was to assess whether a risk factor for colonization (IPC) regardless urinary concentration or results late third-trimester rectovaginal screening cultures (RVSCs).Six hundred and eight pregnant women, with urine specimens cultured between May 2011...
Abstract Objectives To characterize the clonal spread of carbapenem-resistant Klebsiella pneumoniae and Escherichia coli isolates between different healthcare institutions in Catalonia, Spain. Methods Antimicrobial susceptibility was tested by disc diffusion. MICs were determined gradient diffusion or broth microdilution. Carbapenemase production confirmed lateral flow. PCR Sanger sequencing used to identify allelic variants resistance genes. Clonality studies performed PFGE MLST. Plasmid...
We evaluated the analytical performance of fully automated cobas® 6500 urine work area and its components—cobas u 601 cobas 701. The study was conducted at three European centers using un-centrifuged surplus routine samples; all measurements were performed within 2 h sample collection. Precision, carry-over, method comparisons per Clinical Laboratory Standards Institute guidelines. Method comparisons: versus Urisys 2400 411 test strips; 701 KOVA® visual microscopy iQ200 analyzer. Operability...
Data on the benefits of rapid microbiological testing antimicrobial consumption (AC) and resistance patterns (ARPs) are scarce. We evaluated impact a protocol based techniques AC ARP in intensive care (ICU) patients.A retrospective pre- (2018) post-intervention (2019-2021) study was conducted ICU patients. A diagnostic algorithm applied starting 2019 patients with lower respiratory tract infection. The incidence nosocomial infections, ARPs, as DDDs (defined daily doses) were monitored.A...
Coronavirus disease 2019 (COVID-19) is widely spreading and represents a critical threat to global health. In the fight against this pandemic, provincial hospitals urgently need rapid diagnostic of COVID-19 infected patients avoid collapsing emergency units. However, high demand with severe acute respiratory symptoms limits fast delivery results by gold standard method reverse transcription-polymerase chain reaction real time (rRT-PCR) for identification positive pneumonia. The principal aim...
Background: The aim of our study is to investigate variations in crude ICU mortality among patients with ventilator-associated pneumonia (VAP) over the past decade. We also wish identify associated risk factors, evaluate changes aetiology, and assess incidence impact inappropriate empirical antibiotic treatment (IEAT). Methods: conducted a retrospective, observational, single-centre 10-year period (2014-2024), including critically ill who developed VAP. population was divided into three...
Cryoglobulins (CGs) are serum proteins that undergo a reverse cold-induced precipitation in vitro. The CGs well-known cause of analytical interferences several laboratory tests, leading to spurious results. With this view, we present case patient initially misdiagnosed due interference Hepatitis C Virus (HCV) serology.We report woman advanced age affected by acute renal failure required urgent haemodialysis. In the absence infections and other causes production, diagnosis secondary essential...
Resumen Objetivos La enfermedad por coronavirus 2019 (COVID-19) se ha extendido todo el mundo, representando una grave amenaza para la salud mundial. En lucha contra esta pandemia, los hospitales provinciales necesitan diagnosticar rápidamente a pacientes con COVID-19 evitar colapsar servicios de urgencias. Sin embargo, elevada demanda síntomas respiratorios agudos impide envío rápido resultados prueba referencia rRT-PCR, identificación neumonía COVID-19-positiva. El objetivo principal este...