A5032534691- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Antibiotic Resistance in Bacteria
- Infective Endocarditis Diagnosis and Management
- Streptococcal Infections and Treatments
- Microscopic Colitis
- SARS-CoV-2 and COVID-19 Research
- Antifungal resistance and susceptibility
- SARS-CoV-2 detection and testing
- Genomics, phytochemicals, and oxidative stress
- Nosocomial Infections in ICU
- Sepsis Diagnosis and Treatment
- Biosensors and Analytical Detection
- Curcumin's Biomedical Applications
- Viral gastroenteritis research and epidemiology
- Escherichia coli research studies
- Urinary Tract Infections Management
- Inflammatory Bowel Disease
- Soybean genetics and cultivation
- Pharmacological Effects of Natural Compounds
- Long-Term Effects of COVID-19
- Phytoestrogen effects and research
- Patient Satisfaction in Healthcare
Universidad de Cádiz
2013-2024
Biomedical Research and Innovation Institute of Cadiz
2024
Hospital Jerez Puerta del Sur
2016-2024
Hospital Universitario Puerta del Mar
2013
Universidad de Sevilla
2006-2009
Instituto de Gastroenterología
2009
Pseudomonas aeruginosa healthcare-associated infections are one of the top antimicrobial resistance threats world-wide. In order to analyze current trends, we performed a Spanish nation-wide high-resolution analysis susceptibility profiles, genomic epidemiology and resistome P. over five-year time lapse.A total 3.180 nonduplicated clinical isolates from two surveys in October 2017 2022 were analyzed. MICs 13 antipseudomonals determined by ISO-EUCAST. Multidrug (MDR)/extensively drug...
The COVID-19 outbreak has spread extensively around the world. Loss of smell and taste have emerged as main predictors for COVID-19. objective our study is to develop a comprehensive machine learning (ML) modelling framework assess predictive value disorders, along with other symptoms, in infection. A multicenter case-control was performed, which suspected cases COVID-19, who were tested by real-time reverse-transcription polymerase chain reaction (RT-PCR), informed about presence severity...
BackgroundEscherichia coli is the most frequent cause of bloodstream infections (BSIs). About one-third patients with BSIs due to E develop sepsis or shock. The objective this study characterise microbiological features blood isolates causing septic shock provide exploratory information for future diagnostic, preventive, therapeutic interventions.MethodsE from a multicentre cross-sectional older than 14 years presenting (according Third International Consensus Definitions Sepsis and Septic...
Abstract Background Catheter-related bloodstream infections (CRBSIs) increase morbidity and mortality, prolong hospitalization generate considerable medical costs. Recent guidelines for CRBSI recommend empirical therapy against Gram-positive bacteria (GPB) restrict coverage Gram-negative (GNB) only to specific circumstances. Objectives To investigate predictors of GNB aetiology in assess the outcome patients with CRBSI. Methods Patients were selected from PROBAC cohort, a prospective,...
Diagnosing COVID-19-associated pulmonary aspergillosis (CAPA) can be challenging since radiological and clinical criteria in the critically ill patient are nonspecific. Microbiological diagnostic support is therefore crucial. The aim of this study was to document incidence using bronchoalveolar lavage (BAL) as method determine performance current mycological tests most widely used for diagnosis CAPA, together with evaluation Asp lateral flow device (LFD).Prospective cohort conducted between...
Biliary-tract bloodstream infections (BT-BSI) caused by Enterococcus faecalis and E. faecium are associated with inappropriate empirical treatment worse outcomes compared to other etiologies. The objective of this study was investigate the risk factors for enterococcal BT-BSI. Patients BT-BSI from PROBAC cohort, including consecutive patients BSI in 26 Spanish hospitals between October 2016 March 2017, were selected; episodes or causes compared. Independent predictors enterococci identified...
The aim of this study was to investigate the incidence COVID-19-associated pulmonary aspergillosis (CAPA) in critically ill patients and impact anticipatory antifungal treatment on CAPA patients.Before/after observational a mixed intensive care unit (ICU) university teaching hospital. took place between March 2020 June 2022. Inclusion criteria were with severe SARS-CoV-2 pneumonia requiring invasive mechanical ventilation. Two analysis periods compared according whether or not therapy given...
Abstract Curcumin, a polyphenol derived from the plant, Curcuma longa , has variety of pharmacological effects, including chemotherapeutic, anti‐inflammatory, antiangiogenic, and antioxidant activities. To gain better understanding effects mechanisms action curcumin on acute injury caused by intra‐colonic administration acetic acid (AA) in rats, inflammation was assessed histology myeloperoxidase activity (MPO; an index neutrophil infiltration mucosa); Th1 Th2 cytokine production;...
This study aimed to determine the association of Escherichia coli microbiological factors with 30-day mortality in patients bloodstream infection (BSI) presenting a dysregulated response (i.e. sepsis or septic shock).
Abstract Objectives Bloodstream infections (BSI) are an important cause of mortality, although they show heterogeneity depending on patients and aetiological factors. Comprehensive specific mortality scores for BSI scarce. The objective this study was to develop a predictive score in based multicentre prospective cohort. Methods A cohort including consecutive adults with bacteraemia recruited between October 2016 March 2017 26 Spanish hospitals randomly divided into derivation (DC)...
Abstract Importance The actual demand on SARS-CoV-2 diagnosis is a current challenge for clinical laboratories. Sample pooling may help to ameliorate workload in Objective evaluate the efficacy of sample compared individual analysis CoVID-19, by using different commercial platforms nucleic acid extraction and amplification. Design settings observational, prospective, multicentre study across 9 Spanish microbiology laboratories including RNA testing performed April 2020, during first three...
Background: There have been numerous psychological and psychiatric terms recorded in traditional Chinese medical bibliographies, developing a TCM specialty called mental-emotional diseases (神志 病), which symptomatology, etiology, psychopathology, various therapeutic approaches well established.Results: medicine was the mainstay management of mental disorders wellbeing ancient days.It also has increasingly used today's clinical practice aimed to enhance efficacy, reduced adverse effects caused...