A5025064037- Pharmaceutical and Antibiotic Environmental Impacts
- Pesticide and Herbicide Environmental Studies
- Aquaculture disease management and microbiota
- Plant Pathogens and Fungal Diseases
- Viral gastroenteritis research and epidemiology
- Insect Resistance and Genetics
- Plant and Fungal Interactions Research
- Plant-Microbe Interactions and Immunity
- Glycosylation and Glycoproteins Research
- Weed Control and Herbicide Applications
- Genetic diversity and population structure
- Plant pathogens and resistance mechanisms
- Animal Disease Management and Epidemiology
- Viral Infectious Diseases and Gene Expression in Insects
- Influenza Virus Research Studies
- MicroRNA in disease regulation
- RNA Interference and Gene Delivery
- Analytical chemistry methods development
- Plant Pathogens and Resistance
- Photosynthetic Processes and Mechanisms
- Fungal Biology and Applications
- Biofuel production and bioconversion
- Plant Molecular Biology Research
- Plant Gene Expression Analysis
- Agricultural pest management studies
China Agricultural University
2018-2025
Lanzhou Veterinary Research Institute
2020-2025
Chinese Academy of Agricultural Sciences
2011-2025
Shenzhen Institutes of Advanced Technology
2023-2025
Guangdong Academy of Medical Sciences
2025
Southern Medical University
2025
Guangdong Provincial People's Hospital
2025
Yueyang Changling Equipment Research Institute (China)
2024
Shandong Academy of Agricultural Sciences
2012-2024
Institute of Plant Protection
2012-2024
Antibacterial metal ions, such as Ag+, Zn2+ and Cu2+, have been extensively used in medical implants devices due to their strong broad spectrum of antibacterial activity. However, it is still a controversial issue whether they can show the desired activity while being toxic mammalian cells. It very important balance effectiveness with minimal damage Toward this end, study identify suitable concentrations these three ions at which effectively kill two types clinically relevant bacteria...
Certain low pathogenic avian influenza viruses can mutate to highly when they circulate in domestic poultry, at which point cause devastating poultry diseases and severe economic damage. The H7N9 that emerged 2013 China had caused human infections deaths. However, these were nonlethal poultry. It is unknown whether the acquire additional mutations during their circulation nature become lethal more dangerous for humans. Here, we evaluated evolution of isolated from species between 2017 found...
Genetic variation in the IL-7 receptor-α (IL-7R) gene is associated with susceptibility to human type 1 diabetes (T1D). Here we investigate therapeutic efficacy and mechanism of IL-7Rα antibody a mouse model T1D. induces durable, complete remission newly onset diabetic mice after only two three injections. increases, whereas therapy reduces, IFN-γ-producing CD4(+) (T(H)1) CD8(+) T cells. Conversely, decreases enhances inhibitory receptor Programmed Death (PD-1) expression effector blockade...
Abstract BACKGROUND: Wild radish, a problem weed worldwide, is severe dicotyledonous in crops. In Australia, sustained reliance on ALS‐inhibiting herbicides to control this species has led the evolution of many resistant populations endowed by any several ALS mutations. The molecular basis herbicide resistance novel population was studied. RESULTS: gene sequencing revealed previously unreported substitution Tyr for Ala at amino acid position 122 individuals wild radish (WARR30). A purified...
BACKGROUND: Helicoverpa armigera (Hübner) causes severe losses in many crops including cotton. Cytochrome P450s play crucial roles the metabolism of important compounds various organisms. The authors attempt to identify new cytochrome P450 genes and investigate their expression profile xenobiotic response order understand nature this pest. RESULTS: A novel cDNA (CYP9A17), encoding a protein 531 amino acid residues, was isolated from H. armigera. CYP9A17 is typical microsomal P450, showing...
// Xiaolan Zhu 1, 2, * , Huiling Shen 3, Xinming Yin 1 Lulu Long 3 Xiaofang Chen Fan Feng Yueqin Liu Peiqing Zhao 2 Yue Xu Mei Li 4 Wenlin and Yuefeng Department of Gynecologic Oncology, The Fourth Affiliated Hospital Jiangsu University, Zhenjiang, 212001, China Medical School, 212003, People Radiology, These authors are considered as co-first Correspondence to: Xu, email: xwl630806@126.com Li, lxz1986122@sina.com Keywords: miR-204, IL-6R, STAT3, chemoresistance, EOC Received: January 23,...
ABSTRACT The recent emergence of a transferable colistin resistance mechanism, MCR-1, has gained global attention because its threat to clinical treatment infections caused by multidrug-resistant Gram-negative bacteria. However, the possible transmission route mcr-1 among Enterobacteriaceae species in settings is largely unknown. Here, we present comprehensive genomic analysis Escherichia coli isolates collected hospital Hangzhou, China. We found that -carrying from and feces inpatients...
Abstract Mineral granules in the mitochondria of bone‐forming cells are thought to be origin biomineral precursors, which transported extracellular matrices initiate cell‐mediated biomineralization. However, no evidence has revealed how mitochondrial form. This study indicates that initiated by transporting calcium and phosphorus clusters from endoplasmic reticulum (ER) based on detailed observations continuous process mouse parietal bone development as well vitro biomineralization cells....
Brassica napus, a hybrid resulting from the crossing of rapa and oleracea, is one most important oil crops. Despite its significance, B. napus productivity faces substantial challenges due to heavy metal stress, especially in response cadmium (Cd), which poses significant threat among metals. Natural resistance-associated macrophage proteins (NRAMPs) play pivotal roles Cd uptake transport within plants. However, our understanding role BnNRAMPs limited. Thus, this study aimed conduct...
<title>Abstract</title> Bacterial second messenger networks transmit environmental information through both amplitude and frequency modulation strategies. However, the mechanisms by which cells decode frequency-encoded signals remain poorly understood. By reconstructing cAMP system in Pseudomonas aeruginosa, we demonstrate that frequency-to-amplitude signal conversion (FAC) emerges three distinct filtering modules into gene expression patterns. Our mathematical framework predicts high-pass...
Increased insecticide detoxification mediated by cytochrome P450s is a common mechanism of resistance. Although Cyp6a2 has been observed to be overexpressed in many 4,4'-dichlorodiphenyltrichloroethane (DDT)-resistant strains Drosophila melanogaster, how regulated and whether its overproduction confers DDT resistance remain elusive.Molecular analysis identified five alleles (Cyp6a2(Canton) (-S-1) , Cyp6a2(Canton) (-S-2) Cyp6a2(91-C) Cyp6a2(91-R) Cyp6a2(Wisconsin) (-) (WD) ) from four D....
Although melatonin has been shown to exhibit a wide variety of biological functions, its effects on promoting differentiation neural cells remain unknown. Wnt signaling mediates major developmental processes during embryogenesis and regulates maintenance, self-renewal, adult mammalian stem cells. However, the role noncanonical pathway neurogenesis remains poorly understood. In this study, amniotic epithelial ( AECs) were isolated from bovine amnion incubated with various concentrations...
Bruchid beetle (Callosobruchus chinensis) poses a serious threat to the production and storage of mung bean (Vigna radiata). Mapping bruchid resistance (Br) will provide an important basis for cloning responsible gene(s) elucidating its functional mechanism, also facilitate marker-assisted selection in breeding. Here, we report construction genetic linkage groups mapping Br1 locus using RIL population derived from cross between Berken, bruchid-susceptible line, ACC41, bruchid-resistant line....
Continuous cropping of watermelon (Citrullus lanatus) may lead to soil degradation. As a conditioner, microbial agent has great potential in improving function and enhancing plant growth. In this study, we aimed explore how relieves the sickness by analyzing performance, physicochemical properties community structures. Results suggested that treatments significantly changed photosynthetic efficiency upper lower leaves, which helped improve growth watermelon. The single fruit weight, sugar...