A5072760592- Multiple Sclerosis Research Studies
- Polyomavirus and related diseases
- Peripheral Neuropathies and Disorders
- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- RNA regulation and disease
- Viral Infections and Immunology Research
- Herpesvirus Infections and Treatments
- Family Support in Illness
- Ultrasound and Hyperthermia Applications
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lanthanide and Transition Metal Complexes
- SARS-CoV-2 and COVID-19 Research
- Chemokine receptors and signaling
- Biochemical and Structural Characterization
- Multiple Myeloma Research and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Autoimmune and Inflammatory Disorders Research
- Ophthalmology and Eye Disorders
- Phytochemical Studies and Bioactivities
- Patient-Provider Communication in Healthcare
- Acute Lymphoblastic Leukemia research
- Otitis Media and Relapsing Polychondritis
- Mycobacterium research and diagnosis
- Migraine and Headache Studies
University of Parma
2012-2023
Biogen (Italy)
2023
San Raffaele University of Rome
2014
In the COVID-19 pandemic era, safety concerns have been raised regarding risk of severe infection following administration ocrelizumab (OCR), a B-cell-depleting therapy. We enrolled all relapsing remitting multiple sclerosis (RRMS) patients who received maintenance doses OCR from January 2020 to June 2021. Data were extracted in December Standard interval dosing (SID) was defined as regular infusion every 6 months, whereas extended (EID) an delay at least 4 weeks. Three infusions considered...
Abstract Objectives Gray matter ( GM ) damage is well known as a fundamental aspect of multiple sclerosis MS ). Above all, cortical lesions CL s) burden, detectable at MRI with double inversion recovery DIR sequences, has been demonstrated to correlate cognitive impairment CI The aim this study was investigate the role s number in predicting cohort patients clinical practice setting. Materials and methods Thirty consecutive presenting +) high‐field (3.0 T) 3D‐ sequences an even group without...
Background: Few studies have investigated the experiences of patients around conversion to secondary progressive multiple sclerosis (SPMS). ManTra is a mixed-method, co-production research project conducted in Italy and Germany develop an intervention for newly-diagnosed SPMS patients. In previous actions, we identified needs converting via literature review qualitative which involved key stakeholders. Aims: The online patient survey aimed assess, on larger independent sample...
Abstract Introduction EASIER is a multicenter, observational, cross-sectional study investigating the consumption of healthcare resources, including professional (HCP) active working time, costs associated with current natalizumab intravenous (IV) administration, and potential impact adoption subcutaneous (SC) route. Methods The has three parts: (1) time motion to measure resources needed for IV administration using digital data collection tool operated directly by HCPs; (2) HCP structured...
The SIMS-Trial showed that the 'Sapere Migliora' information aid (IA) for newly diagnosed people with multiple sclerosis (PwMS) effectively improved patient knowledge and satisfaction care.The objectives of this paper are to assess effectiveness IA in clinical practice compare whole take-home booklet/website component alone.After updating replacing CD a website, prospective, open-label non-randomised controlled trial compared (group A, five centres) B, 16 centres). One month after...
Known risk factors for multiple sclerosis (MS) include smoking, a low vitamin D status, obesity, and EBV, while the inflammatory feature of disease strongly suggests presence additional infectious agents. The association between use antibiotics MS that could shed light on these is still undetermined. We aimed to evaluate risk, in Emilia-Romagna region (RER), Italy.All adult patients with seen at any RER center (2015-2017) were eligible. For each 877 included, clinical information was...
Background: multiple sclerosis (MS) has an extremely heterogeneous disease course. Relapsing course leading to rapid accrual of physical and cognitive disability, often despite treatment, is referred as "aggressive" disease. Case presentation: definition treatment aggressive are poorly standardized. No clear reports ocrelizumab in tumefactive, breakthrough available current literature. report: a 34-year-old Caucasian woman was admitted hospital with dizziness, nausea, vomiting, mild gait...
Abstract Objectives/Background Tension‐type headache and migraine without aura are the most common primary headaches occurring in people with demyelinating diseases, whereas cluster (CH) can be considered exceptional. The location of lesions could strategic these cases, involving areas interacting trigeminovascular system. Methods Results We report a case 54‐year‐old woman right‐sided CH as initial manifestation multiple sclerosis showing left dorsal brainstem lesion on magnetic resonance...
Background and purpose Dimethyl fumarate (DMF) causes a mean lymphocyte count drop of approximately 30% in relapsing–remitting multiple sclerosis (RRMS) patients. The relationship between this reduction DMF effectiveness is controversial. objective was to investigate if the decrease absolute (ALC) from baseline during treatment associated with clinical magnetic resonance imaging (MRI) disease activity. A secondary aim evaluate ALC variations over time real‐life cohort DMF‐treated Methods...
The recent improvements in multiple sclerosis therapy have lead to consequent its prognosis: however, it still remains a chronic and unpredictable disease. moment of the diagnosis is starting point durable relationship between physician patient, but, most all, often referred as traumatic experience patients’ life. Patients’ compliance prescribed therapies, so important course every condition, particularly hangs on psychological approach used by doctor communicating explaining for first time,...