Giancarlo Di Battista
A5101520667- Multiple Sclerosis Research Studies
- Polyomavirus and related diseases
- Systemic Sclerosis and Related Diseases
- Rheumatoid Arthritis Research and Therapies
- Peripheral Neuropathies and Disorders
- Acute Lymphoblastic Leukemia research
- Autoimmune and Inflammatory Disorders Research
- Systemic Lupus Erythematosus Research
- Immunotherapy and Immune Responses
- Neurology and Historical Studies
- Cardiovascular Syncope and Autonomic Disorders
- Heart Rate Variability and Autonomic Control
- Drug-Induced Hepatotoxicity and Protection
- Migration, Health and Trauma
- Liver Disease Diagnosis and Treatment
- Amyotrophic Lateral Sclerosis Research
- Hepatitis C virus research
- Retinal and Optic Conditions
- Vaccine Coverage and Hesitancy
- Ion channel regulation and function
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cerebral Palsy and Movement Disorders
- Intraocular Surgery and Lenses
- Infectious Diseases and Tuberculosis
- Family and Disability Support Research
Multiple Sclerosis Foundation
2022
Istituti di Ricovero e Cura a Carattere Scientifico
2021
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2021
Vita-Salute San Raffaele University
2021
Ospedale San Filippo Neri
1985-2020
Associazione Italiana Sclerosi Multipla
2020
ASL Roma
2016-2019
University of Parma
2014
Azienda USL di Pescara
2009
An ever-expanding number of disease-modifying drugs for multiple sclerosis have become available in recent years, after demonstrating efficacy clinical trials. In the real-world setting, however, are prescribed patient populations that differ from those included pivotal studies, where extreme age patients usually excluded or under-represented. this multicentre, observational, retrospective Italian cohort study, we evaluated treatment exposure three cohorts with relapsing-remitting defined by...
Hyperthermia, with no signs of any underlying infection, may occur in the course neuroleptic malignant syndrome, fatal catatonia, heat stroke, or hyperthermia. We describe hyperthermia as a complication after discontinuance antiparkinsonian treatment levodopa/carbidopa and bromocriptine. Impaired nigrostriatal, hypothalamic, mesolimbic dopaminergic functions could be involved pathogenesis.
Background and Purpose— We sought to determine whether the introduction of EEG monitoring during head-up tilt testing could significantly improve understanding cerebral events occurring tilt-induced vasovagal syncope potential danger patient this diagnostic procedure. Methods— was performed in a group 63 consecutive patients (27 males 36 females; mean age, 41.5 years) with history recurrent unknown origin despite extensive clinical laboratory assessment. Results— Syncope occurred 27 (42.8%)...
Except for ocrelizumab, treatment options in primary progressive multiple sclerosis (PPMS) are lacking.To investigate the effectiveness of DMTs on risk becoming wheelchair dependent a real-world population patients with PPMS.This was multicenter, observational, retrospective, comparative research study. Data were extracted November 28, 2018, from Italian register and analyzed June to December 2021. Mean study follow-up 11 years. Included cohort diagnosis PPMS at least 3 years Expanded...
Background: The prevalence of multiple sclerosis varies considerably throughout the world. Objective: To better define MS in central Italy. Methods: This is a population-based study conducted province Frosinone, which situated Lazio region, selected day was 1 January 2007. A total 467 patients, with definite diagnosis sclerosis, were considered for crude, age- and sex-specific estimation. Results: overall crude rate 95.0 cases per 100,000 (95% confidence interval (CI) 86.6—104.0)....
The purpose of this study was to assess the adherence therapy in patients with relapsing remitting multiple sclerosis (RR-MS) and analyze possible influence factors such as hospital care socioeconomic status. Two hundred eighty-five RR-MS according Mc Donald's criteria naïve disease-modifying drugs (DMDs) were enrolled. self-administered questionnaires addressing management at prescription personal perception daily life changes caused by DMDs administered months 3 12. Full adherence,...
The SIMS-Trial showed that the 'Sapere Migliora' information aid (IA) for newly diagnosed people with multiple sclerosis (PwMS) effectively improved patient knowledge and satisfaction care.The objectives of this paper are to assess effectiveness IA in clinical practice compare whole take-home booklet/website component alone.After updating replacing CD a website, prospective, open-label non-randomised controlled trial compared (group A, five centres) B, 16 centres). One month after...
Objective To investigate clinical and radiological outcomes of women with relapsing-remitting multiple sclerosis (RRMS) undergoing abortion. Methods An independent, multicentre retrospective study was conducted collecting data from eight Italian MS centres. We compared the preconception postabortion annualised relapse rate (ARR) number Gadolinium enhancing (Gd+) lesions, by analyses covariance. Variables associated MRI activity were investigated using Poisson regression models; each abortion...
Neuropsychiatric abnormalities are frequently reported in patients with multiple sclerosis (MS). Previous studies have investigated the neurotic aspects of psychopathology, and importance personality structure underlying symptoms has only recently been reconsidered. The aim our study was to investigate frequency type profiles MS using Millon Clinical Multiaxial Inventory-III (MCMI-III). We evaluated 77 nondemented physical disability scales self-report questionnaires focused on mood,...
Purpose: Domestic accidents are widespread, but no data available on their occurrence in pathological populations such as patients with multiple sclerosis (MS). Aim was to investigate domestic habits and of different types near falls a sample MS compared healthy controls determine whether patients' linked any disease characteristics. Method: Descriptive survey 50 controls. Participants were administered an ad-hoc questionnaire collect they had the past 2 months. Their physical...
Introduction Immunosuppressive agents (ISA) have been used in multiple sclerosis (MS) for decades, frequently as off label licensed therapies. Given the new MS treatment landscape, what place do ISA combating MS? Methods We conducted a retrospective multicentre study to investigate frequency of prescription 17 Italian centres, and describe clinical factors related use. Results Out 6,447 patients, 2,034 (31.6%) were treated with ISA, Azathioprine being most overall. patients alone more...
Electroencephalographic (EEG) monitoring was performed during head-up tilt testing (HUT) in a group of 63 consecutive patients (27 males, 36 females, mean age 41.5 years) with history recurrent syncope unknown origin despite extensive clinical and laboratory evaluation. Syncope occurred 27/63 (42.8%) HUT cardioinhibitory 11/27 (40.7%) vasodepressor 16/27 (59.3%). All negative response to had no significant EEG modifications. In generalized high amplitude 4-5 Hz (theta range) slowing activity...
<b><i>Background:</i></b> Limited data are available on the prevalence of multiple sclerosis (MS) in central Italy. The objective this study is to estimate MS metropolitan area Rome. <b><i>Methods:</i></b> We used capture-recapture method calculate estimates area. selected day was December 31, 2015. A total 1,007 patients, with a definite diagnosis according revised McDonald’s criteria, were considered for crude, age- and sex-specific...
<b><i>Objectives:</i></b> To investigate whether clinical and magnetic resonance imaging (MRI) outcomes of patients with multiple sclerosis (MS) who required a reduction administration frequency interferon-beta (IFNB) were similar to those did not. <b><i>Methods:</i></b> We identified three subgroups under treatment for 24 months subcutaneous (sc) high-frequency IFNB-1a or -1b: continuing receive IFNB according the drug label (recommended...
Recent studies suggest that patients with Multiple Sclerosis (MS) might be at risk of unemployment due to physical and psychological symptoms. Furthermore, MS appear more exposed a higher level occupational stress, which linked some personality characteristics. Our aim was ascertain, by means longitudinal study, whether changes in stress can predicted traits, could thereby become potential targets therapeutic interventions. This study describes the results previous work on traits patients....
Despite intensified global efforts, the number of cases tuberculosis worldwide is increasing. In patients treated with antimycobacterial agents, major adverse events are generally uncommon. Here we report a case acute renal failure and immune hemolytic anemia in patient receiving antitubercular therapy. Rifampicin-related toxicity well-defined clinical entity, probably an underestimated incidence. It typically occurs after reintroduction rifampicin previously patients. Immune anemia, liver...