A5066465731- Retinal and Macular Surgery
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Semiconductor Quantum Structures and Devices
- Intraocular Surgery and Lenses
- Advanced Semiconductor Detectors and Materials
- Retinal Development and Disorders
- Polymer Surface Interaction Studies
- Surface Modification and Superhydrophobicity
- Semiconductor materials and interfaces
- Electrospun Nanofibers in Biomedical Applications
- Retinal Diseases and Treatments
- Surface and Thin Film Phenomena
- Glaucoma and retinal disorders
- Bone Tissue Engineering Materials
- Solid-state spectroscopy and crystallography
- 3D Printing in Biomedical Research
- Corneal surgery and disorders
- Semiconductor materials and devices
- Vehicle emissions and performance
- Electron and X-Ray Spectroscopy Techniques
- Particle Detector Development and Performance
- Orthopaedic implants and arthroplasty
- Air Quality and Health Impacts
- Species Distribution and Climate Change
University of Liverpool
2015-2024
University of South Carolina
2024
University College London
2002-2024
Great Ormond Street Hospital
2024
St George's Hospital
2014-2023
Mission Therapeutics (United Kingdom)
2023
Sheffield Hallam University
2023
University Hospitals Plymouth NHS Trust
2022
University of California, Berkeley
2022
Charles River Laboratories (United Kingdom)
2021-2022
Image segmentation is an important step in medical image processing and has been widely studied developed for refinement of clinical analysis applications. New models based on deep learning have improved results but are restricted to pixel-wise fitting the map. Our aim was tackle this limitation by developing a new model which takes into account area inside as well outside region interest size boundaries during learning. Specifically, we propose loss function incorporates information...
Abstract Viral clearance, antibody response and the mutagenic effect of molnupiravir has not been elucidated in at-risk populations. Non-hospitalised participants within 5 days SARS-CoV-2 symptoms randomised to receive (n = 253) or Usual Care 324) were recruited study viral dynamics on whole genome sequence from 1437 genomes. Molnupiravir accelerates load decline, but virus is detectable by Day most cases. At 14 (9 post-treatment), associated with significantly higher persistence lower...
We compared pregnancy outcomes among United States-born and Mexican-born women having Spanish surnames with US-born Whites Blacks using California's 1981 matched birth-death cohort file. Maternal risk characteristics between Black were similar. In contrast, Latino women, regardless of national origin, delivered small proportions low weight infants as to Blacks. Birthweight-specific mortality rates during the fetal neonatal periods for offspring surname generally higher than those other...
Abstract Mutations in SNCA, the gene encoding α-synuclein (αSyn), cause familial Parkinson’s disease (PD) and aberrant αSyn is a key pathological hallmark of idiopathic PD. This α-synucleinopathy leads to mitochondrial dysfunction, which may drive dopaminergic neurodegeneration. PARKIN PINK1, mutated autosomal recessive PD, regulate preferential autophagic clearance dysfunctional mitochondria (“mitophagy”) by inducing ubiquitylation proteins, process counteracted deubiquitylation via USP30....
Abstract Polytetrafluoroethylene (PTFE) was treated in a low‐power plasma using series of feed gases (O 2 , Ar, N and NH 3 ) the resulting surface modifications were evaluated by x‐ray photoelectron spectroscopy, static secondary ion mass dynamic contact angle measurements atomic force microscopy. All treatments caused light etching, but nature extent chemical modification varied considerably. Fluorine depletion affected most efficiently Ar least effectively O plasma. New functionalities...
Blood pressure and heart rate response to pharmacologic autonomic blockade were studied in the 31 fetuses of 27 time-dated pregnant sheep from 85 150 days gestation 5 neonatal lambs. A fetal hind limb vein either a femoral or carotid artery cannulated following at least 2 days’ recovery surgery, over several while ewes stood undisturbed. The degree control exerted by nervous system fetus was examined selective parasympathetic, α- β-adrenergic, components. Evidence activity found all ages...
The quantum-mechanical convergent kinetic equation of Gould and DeWitt is used for the calculation static transport coefficients through first order in plasma parameter a fully ionized, nondengenerate, two-component near thermal equilibrium. solved with standard Chapman-Enskog procedure using three-term Sonine polynomial expansion. Since close collisions dynamic screening effects are treated correctly, results contain both logarithmic (dominant) nonlogarithmic (subdominant) terms evaluated...
We report an increase in GII.17 norovirus outbreaks and sporadic infections of acute gastroenteritis Austria, Germany, France, Ireland, the Netherlands, England United States during 2023/24 season. A decrease GII.4 coincided with prevalence increasing to between 17% 64% all GII detections. Overall, 84% strains clustered closely first reported Romania 2021 two new sub-lineages were identified. Norovirus surveillance molecular characterisation should be prioritised this winter.