Lijun Zheng

ORCID: 0000-0002-2890-7494
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Research Areas
  • Gastrointestinal Tumor Research and Treatment
  • Gastric Cancer Management and Outcomes
  • Pancreatitis Pathology and Treatment
  • Tuberculosis Research and Epidemiology
  • Diagnosis and treatment of tuberculosis
  • Liver Disease Diagnosis and Treatment
  • Facial Rejuvenation and Surgery Techniques
  • HER2/EGFR in Cancer Research
  • Berberine and alkaloids research
  • Traditional Chinese Medicine Analysis
  • Mycobacterium research and diagnosis
  • Intraocular Surgery and Lenses
  • Bariatric Surgery and Outcomes
  • Metastasis and carcinoma case studies
  • Colorectal Cancer Surgical Treatments
  • Reconstructive Facial Surgery Techniques
  • Reconstructive Surgery and Microvascular Techniques
  • Cancer, Lipids, and Metabolism
  • Pulmonary Hypertension Research and Treatments
  • Biomarkers in Disease Mechanisms
  • Phagocytosis and Immune Regulation
  • Ocular Infections and Treatments
  • Medicinal Plant Pharmacodynamics Research
  • Surgical Simulation and Training
  • Cardiovascular Disease and Adiposity

Cancer Hospital of Huanxing Chaoyang District Beijing
2025

University of Electronic Science and Technology of China
2024

Nanjing Traditional Chinese Medicine Hospital
2024

Shanghai Tenth People's Hospital
2009-2023

Tongji University
2009-2021

The Third People's Hospital of Dalian City
2021

Capital Medical University
2019-2020

Beijing Chest Hospital
2019-2020

Weatherford College
2019

Chengdu University
2018

We aimed to evaluate clinical symptoms in diarrhea predominant irritable bowel syndrome (IBS‐D) receiving berberine hydrochloride a randomized double‐blind placebo‐controlled trial. Overall, 196 patients with IBS‐D were recruited for this study; consequently, 132 receive daily 400 mg of hydrochloride, delivered twice or placebo 8 weeks followed by 4‐week washout period. After 2‐week run‐in period, diarrhea, abdominal pain, urgent need defecation frequency and any adverse events recorded...

10.1002/ptr.5475 article EN Phytotherapy Research 2015-09-24

Background and Aims Berberine its derivatives display potent analgesic, anti-inflammatory anticancer activity. Here we aimed at characterizing the mechanism of action berberine in gastrointestinal (GI) tract cortical neurons using animal models vitro tests. Methods The effect was characterized murine mimicking diarrhea-predominant irritable bowel syndrome (IBS-D) symptoms. Then opioidantagonists were used to identify receptors involved. Furthermore, berberineon opioid expression established...

10.1371/journal.pone.0145556 article EN cc-by PLoS ONE 2015-12-23

Limited real-world efficacy and safety data exist regarding the use of trastuzumab deruxtecan (T-DXd) in Chinese population with human epidermal growth factor receptor (HER2)-positive HER2-low advanced breast cancer (BC). This multicenter, observational, study aimed to evaluate T-DXd for treatment patients HER2-positive BC. The medical records 61 were collected from Second Hospital Dalian Medical University, Beijing Chaoyang District Sanhuan Cancer Hospital, Jingxin Academy Sciences. primary...

10.1177/17588359251318853 article EN cc-by-nc Therapeutic Advances in Medical Oncology 2025-01-01

Schwannomas are tumors arising from the nervous system that also occur infrequently in gastrointestinal tract, most commonly stomach. This report characterizes 29 patients with benign or malignant gastric schwannomas. Surgical data and clinical follow-up information were available for 28 cases a median postoperative duration of 57 months. Clinicopathological immunohistochemical characteristics schwannomas analysed. Four (13.7%) histologically diagnosed schwannoma. All positive S-100 CD56...

10.1155/2014/202960 article EN cc-by Gastroenterology Research and Practice 2014-01-01

We conducted our meta-analysis to compare outcomes between laparoscopic resection and open for gastric gastrointestinal stromal tumors (GISTs) from all published comparative studies in the literature. Databases, including PubMed, Embase, Cochrane Library, Ovid, Web of Science, CNKI, were searched identify comparing after GISTs. The was performed by RevMan 5.1. Eleven comprising 495 patients identified. Patients undergoing GISTs found have similar operative time (weighted mean difference...

10.1177/000313481408000124 article EN The American Surgeon 2014-01-01

Intelligent hypertension excellence centers (iHEC) may improve blood pressure (BP) management in older hypertensive patients. However, this has not yet been rigorously evaluated, so we conducted a prospective randomized open-label clinical trial to verify hypothesis. Older patients with were recruited between January and June 2022. The control group received conventional treatment visited doctors clinic. intervention the iHEC therapy model, including remote BP management, online...

10.1038/s41440-024-01951-w article EN cc-by Hypertension Research 2024-11-06

Background: Polyacrylamide hydrogel has been used for soft-tissue augmentation more than 10 years. Although it is considered a nontoxic, nonimmunogenic material, complications after polyacrylamide injections during facial have reported. Methods: Between 2003 and 2009, 24 patients underwent surgical management of augmentation. Histories, preoperative imaging, photographs operations were recorded. Results: Complications included hematomas, infection, nodule formation, migration. Ultimately, 23...

10.1097/prs.0b013e3182589b7d article EN Plastic & Reconstructive Surgery 2012-08-01

The mechanisms facilitating hypertension in diabetes still remain to be elucidated. Nonalcoholic fatty liver disease (NAFLD), which is a higher risk factor for insulin resistance, shares many predisposing factors with diabetes. However, little work has been performed on the pathogenesis of type 2 (T2DM) NAFLD. aim this study investigate prevalence different glycemic statuses and analyze relationships between NAFLD, metabolic risks, within large community-based population after informed...

10.1155/2017/5262560 article EN cc-by International Journal of Endocrinology 2017-01-01

BACKGROUNDIntravitreal injection has become an efficient approach for delivering drugs at therapeutic levels to the posterior segment in retinal diseases.However, increased frequency and number of intravitreal injections have raised concerns about their side effects.As manipulation during surgery is relatively simple, details procedure are easily overlooked.Iatrogenic crystalline lens injury a rare complication caused by improper surgical procedures.We report two cases triamcinolone...

10.12998/wjcc.v7.i22.3784 article EN World Journal of Clinical Cases 2019-11-26

Abstract Background Although the incidence of co‐existent pulmonary tuberculosis (PTB) and lung cancer in China is increasing, risk factors related to its development are still poorly understood. We aimed investigate which clinical were associated with odds PTB (PTB‐lung cancer) cases a case‐control study. Method A total 125 PTB‐lung patients enrolled by Beijing Chest Hospital as case group between January 2012 December 2016. Age‐ sex‐matched PTB‐only (N = 125) cancer‐only selected control...

10.1111/eci.13432 article EN European Journal of Clinical Investigation 2020-10-14

Non-small cell lung cancer (NSCLC) is a leading cause of death worldwide. The upregulation the epidermal growth factor receptor (EGFR) due to mutations has been observed in number cancers, and tyrosine kinase inhibitors (TKIs), such as gefitinib erlotinib, which specifically target EGFR signaling, have used treat NSCLC patients. presence was previously shown confer sensitivity TKIs. In this study, we evaluated correlation between response erlotinib Chinese We recruited 36 patients with stage...

10.5301/jbm.5000059 article EN The International Journal of Biological Markers 2014-04-01

Gastric cancer (GC) is a prevalent malignant tumor of the digestive system, characterized by poor prognosis and high recurrence rate. Perineural invasion (PNI), neoplastic infiltration nerves, significant predictor survival outcome in GC. Accurate preoperative identification PNI could facilitate patient stratification optimal treatment. We therefore established validated risk assessment model for GC patients with PNI.

10.21037/tcr-24-481 article EN Translational Cancer Research 2024-10-01

Integrated avulsion of the nipple by human bite is not common. We treated a patient whose left had been completely avulsed modifing as free skin graft and reconstructing pillar-like fascia flap core to reshape configuration nipple.

10.3109/2000656x.2012.748318 article EN Journal of Plastic Surgery and Hand Surgery 2013-05-22

Xu, Jing-hong MD, PhD; Zeng, Bi-Wei MD; Shen, Hui Zheng, Li-Jun Xiao, Wei Murtaza, Ali MD Author Information

10.1111/j.1524-4725.2011.02290.x article EN Dermatologic Surgery 2012-01-23

To evaluate the efficacy and toxicity of palonosetron for prevention vomiting induced by high dose cisplatin-based chemotherapy.One-hundred twenty-eight patients received tropisetron 5 mg plus dexamethasone 10 at first cycle or 0.25 mg, respectively, each administered 30 min before initiation chemotherapy. observe remission rate acute emetic episodes delayed episodes, adverse effects daily food-intake in after chemotherapy.The complete response (CR) rates were not significantly different...

10.3760/cma.j.issn.0253-3766.2012.03.015 article EN PubMed 2012-03-01

Hydroxyapatite [Ca 10 (PO 4 ) 6 (OH) 2 ] is the one of major inorganic constituents natural bone, which has been broadly used in medical and biological applications. The present research work reports on preparation hydroxyapatite nanoparticles (HA NPs) via a green eco-friendly approach based use pectin. crystalline size, purity morphology as-fabricated HA NPs were studied by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, energy dispersive (EDAX) spectroscopic...

10.1166/sam.2020.3599 article EN Science of Advanced Materials 2019-10-15

To evaluate the value of Xpert MTB/RIF in diagnosis pulmonary tuberculosis (PTB) general hospitals, which are usually where patients first visit. Presumptive PTB patients, based on imaging results, a hospital China, were enrolled from August 2015 to April 2017. The sensitivity and specificity four (TB) detection methods, including sputum smear, MTB/RIF, T-SPOT.TB TB-DNA studied. predict effectiveness different combinations assessed using receiver operating characteristic (ROC) curve. 283...

10.1016/j.jrid.2020.02.002 article EN Radiology of Infectious Diseases 2019-12-01
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