A5100641289- Mathematical and Theoretical Epidemiology and Ecology Models
- Radiomics and Machine Learning in Medical Imaging
- Evolution and Genetic Dynamics
- Prenatal Screening and Diagnostics
- Cancer Cells and Metastasis
- Fetal and Pediatric Neurological Disorders
- Clinical Laboratory Practices and Quality Control
- Gastric Cancer Management and Outcomes
- Cancer Genomics and Diagnostics
- Alzheimer's disease research and treatments
- Cleft Lip and Palate Research
- AI and Multimedia in Education
- Sepsis Diagnosis and Treatment
- Retinal Imaging and Analysis
- Pregnancy and Medication Impact
- Herbal Medicine Research Studies
- Telomeres, Telomerase, and Senescence
- MRI in cancer diagnosis
- Traditional Chinese Medicine Studies
- Liver Diseases and Immunity
- Educational Technology and Pedagogy
- Blood Pressure and Hypertension Studies
- Advanced Technologies in Various Fields
- Obstructive Sleep Apnea Research
- Kruppel-like factors research
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2024
Shandong University of Traditional Chinese Medicine
2023
Nanjing University of Chinese Medicine
2022
Jiangsu Province Hospital
2022
Jinan University
2009-2022
Southern University of Science and Technology
2022
Xinyu University
2021
RTI Health Solutions
2018
Nanjing Medical University
2018
Nanjing Drum Tower Hospital
2016-2017
Objective To profile gut microbiome-associated metabolites in serum and investigate whether these could distinguish individuals with colorectal cancer (CRC) or adenoma from normal healthy individuals. Design Integrated analysis of untargeted metabolomics by liquid chromatography-mass spectrometry metagenome sequencing paired faecal samples was applied to identify significantly altered abundance patients CRC adenoma. The ability discriminate between tested targeted metabolomic analysis. A...
As the demand for mineral raw materials continues to grow, frequency of mining has increased year by year. Quickly and accurately identifying boundaries become one core issues in management. Aiming at problems complex feature scenes ambiguous boundary features open pit areas, this paper proposes an innovative USF-Net method, which combines SAM with task-specific knowledge effectively improve recognition accuracy boundaries. By merging generic from model specific requirements mine extraction...
Abstract Background Chronic myeloid leukemia is a clonal myeloproliferative disorder disease in which BCR/ABL plays an important role as oncoprotein and molecular target. Despite the success of targeted therapy using tyrosine kinase inhibitors, CML remains largely incurable, most likely due to treatment resistance after firstly chemical therapy. So know well unique pathway very important. Methods The expressions CD44 different patients cell lines were detected by real-time PCR western...
Purpose To investigate the efficacy of histogram analysis entire tumor volume in apparent diffusion coefficient (ADC) maps for differentiating between histological grades gastric cancer. Materials and Methods Seventy-eight patients with cancer were enrolled a retrospective 3.0T magnetic resonance imaging (MRI) study. ADC obtained at two different b values (0 1000 sec/mm2) each patient. Tumors delineated on slice maps, was subsequently generated. A series parameters (eg, skew kurtosis)...
To analyze the clinical relevance of heterogeneous phenotypes peripheral circulating tumor cells (CTCs) in non-small cell lung cancer (NSCLC).CTCs 5 mL venous blood were enriched using Canpatrol™ CTC technique 82 NSCLC patients. And then, CTCs subjected to RNA situ hybridization with a combination epithelial (EpCAM and CK8/18/19) mesenchymal (vimentin TWIST1) markers.According fluorescent dots, classified into three groups, including (E-CTC), hybrid epithelial/mesenchymal (E/M-CTCs)...
Minimally invasive endoscopic haematoma evacuation is widely used in the treatment of intraventricular haemorrhage. However, its technique still has room for improvement. A new modified neuroendoscope technology (MNT) was this study and we explored safety efficacy severe acute haemorrhage by comparing it with extraventricular drainage plus urokinase thrombolytic (EVD + UT) therapy.The following parameters were compared between MNT group control group: incision design, operation time, ICU...
This study intended to investigate the independent effect of admission heart rate (HR) on risk major adverse cardiovascular events (MACEs) in acute myocardial infarction (AMI) patients with different left ventricular ejection fraction (LVEF) levels.The was a secondary analysis Acute Coronary Syndrome Quality Improvement Kerela Trial. The relationship between HR and 30-day outcomes AMI LVEF levels detected using Logistic regression model. Interaction tests were used compare effects subgroups...
Background To establish and validate an laboratory information system (LIS)‐based auto‐verification (AV) by using large amounts of biochemical test results in cancer patients. Methods An algorithm the AV process was designed for pre‐analysis, analysis, post‐analysis. The limit range check adjusted three times, while delta criteria were first replaced same patients’ historical extremum results. rules 51 items tested data 121 123 samples (6 177 273 tests) 2016 that manually reviewed through...
In this work, we construct a stage-structured single population system with winter hibernation and impulsive effect in polluted environment. All solutions of the investigated are proved to be uniformly ultimately bounded. The conditions population-extinction solution obtained. permanent condition is also Finally, numerical analysis inserted illustrate results. Our results indicate that environmental pollution will reduce biological diversity natural world. provide reliable tactic basis for...
A Holling I predator-prey model with mutual interference concerning pest control is proposed and analyzed. The prey predator are considered to be a natural enemy, respectively. forced by the addition of periodic impulsive terms representing import (biological control) pesticide application (chemical at different fixed moments. By using Floquet theory small amplitude perturbations, we show existence stability pest-free solutions. Further, prove that when solutions lost, system permanent...
Scope High salt (HS) diets are related to cardiovascular diseases, and prenatal HS was suggested increase risks of coronary artery diseases in the offspring. This study tested hypothesis that may influence Adenosine‐induced vasodilatation via protein kinase A (PKA) pathway arteries. Methods results Sprague–Dawley rats were fed with 8% diet for gestation, control 0.3% diet. Coronary arteries from male adult offspring K + channels Adenosine signal pathways. Adenosine‐mediated reduced HS. There...
To investigate EMT phenotype and SALL4 expression of circulating tumour cells (CTCs) in patients with gestational trophoblastic neoplasm (GTN).CanPatrol CTC detection system combination RNA situ hybridization was used to the profile CTCs different types disease (GTD). Circulating were phenotyped annotated 41 GTD patients, including 12 HM 29 GTN, as well 22 pregnant volunteers.A positive correlation between number serum β-hCG concentration found among GTN patients. The E/M-CTC positively...
IntroductionClostridium perfringens sepsis is a rare but serious clinical syndrome that typically triggered by gastrointestinal disorders. We present case of bloodstream infection caused Clostridium in liver cancer patient after comprehensive multicourse treatment.Case presentationsThe patient, 68-year-old male, experienced nausea, decreased appetite, and abdominal distension on the 15th day receiving treatment transcatheter arterial chemoembolization (TACE). During admission, he developed...