A5046968847- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Insect symbiosis and bacterial influences
- Vector-Borne Animal Diseases
- Vector-borne infectious diseases
- Dengue and Mosquito Control Research
- Malaria Research and Control
- Insect Pest Control Strategies
- Insect and Pesticide Research
- Bartonella species infections research
- Insect Resistance and Genetics
- Rabies epidemiology and control
- Dermatological diseases and infestations
- Venomous Animal Envenomation and Studies
- Plant Virus Research Studies
- Forensic Entomology and Diptera Studies
- Identification and Quantification in Food
- Insects and Parasite Interactions
- Zoonotic diseases and public health
- Bird parasitology and diseases
- Ion channel regulation and function
- Parasite Biology and Host Interactions
- Neurobiology and Insect Physiology Research
- Avian ecology and behavior
- Entomopathogenic Microorganisms in Pest Control
National Institute of Infectious Diseases
2016-2025
Yamaguchi University
2022
Okayama University of Science
2022
Yamaguchi Prefecture Central Hospital
2022
University of Niigata Prefecture
2022
St. Marianna University School of Medicine
2021
Nagasaki University
2021
National Institute for Japanese Language and Linguistics
2021
Tottori University
2021
The University of Tokyo
2018-2019
Japanese encephalitis (JE) remains a public health concern in several countries, and the Culex mosquito plays central role its transmission cycle. mosquitoes harbor wide range of viruses, including insect-specific viruses (ISVs), can transmit variety arthropod-borne (arboviruses) that cause human animal diseases. The current trend studies displays enhanced efforts to characterize virome through bulk RNA sequencing due possible arbovirus–ISV interactions; however, extent viral diversity taxon...
IntroductionAedes albopictus (Skuse) is an important vector of arboviral diseases, including dengue, chikungunya and Zika virus disease. Monitoring insecticide resistance mechanisms by which the mosquito develops crucial to minimise disease transmission.AimTo determine status in Ae. from different geographical regions.MethodsWe sampled 33 populations Asia, Europe South America, tested these for susceptibility permethrin, a pyrethroid insecticide. In resistant populations, target site...
Aedes aegypti (Linnaeus, 1762) is the main mosquito vector for dengue and other arboviral infectious diseases. Control of this important highly relies on use insecticides, especially pyrethroids. The high frequency (>78%) L982W substitution was detected at target site pyrethroid insecticide, voltage-gated sodium channel (Vgsc) A. collected from Vietnam Cambodia. Alleles having concomitant mutations + F1534C V1016G were also confirmed in both countries, their (>90%) Phnom Penh, Strains these...
Trench fever is a body louse-borne disease caused by Bartonella quintana Brenner. The recent status of louse infestation in Nepalese children not well known. We collected head and lice, Pediculus humanus capitis De Geer L., respectively, from 30 children, including 11 cases double with both lice. Detection B. species identified was carried out polymerase chain reaction (PCR). PCR products DNA sequences were detected lice two as derived other children. These results demonstrate that may also...
During the outbreak of highly pathogenic avian influenza that occurred in Tamba Town, Kyoto Prefecture 2004, a total 926 flies were collected from six sites within radius 2.3 km poultry farm. The H5 A virus genes detected intestinal organs, crop, and gut two blow fly species, Calliphora nigribarbis Aldrichina grahami, by reverse transcription-polymerase chain reaction for matrix protein (M) hemagglutinin (HA) genes. HA gene encoding multiple basic amino acids at cleavage site indicated this...
To evaluate the vectorial capacity of mosquitoes for viruses in Japan, host-feeding habits were analyzed by sequencing polymerase chain reaction-amplified fragments cytochrome b and 16S ribosomal RNA regions mitochondrial DNA 516 15 species from seven genera that collected residential areas during 2003-2006. Culex pipiens L. Aedes albopictus Skuse most commonly urban suburban areas. Anautogenous pallens Coquillett was distinguished autogenous Cx. form molestus Forskal using a reaction-based...
A total of 160 autochthonous dengue cases transmitted by Aedes albopictus were reported between August and October 2014 in Tokyo Metropolis, Japan. Ae. is a medically important vector virus, which has expanded its geographic distribution temperate regions. Understanding the biting density during outbreak to evaluate epidemic risks fever other highly populated cities Europe Asia. Of patients, 134 visited same park (Yoyogi Park) located central Tokyo. Mosquitoes infected with virus collected...
Superinfection exclusion is generally defined as a phenomenon in which pre-existing viral infection prevents secondary infection; this has also been observed infections with mosquito-borne viruses. In study, we examined the superinfection of vertebrate-infecting flaviviruses, Japanese encephalitis virus (JEV) and dengue (DENV), by stable persistent an insect-specific flavivirus, Culex flavivirus (CxFV), tritaeniorhynchus Giles cell line (CTR cells). Our experimental system was designed based...
In 2014 in Japan, 162 autochthonous dengue cases were reported for the first time nearly 70 years. Here, we report results of detection and isolation virus (DENV) from mosquitoes collected Tokyo Metropolis 2015. The phylogenetic relationship among DENV isolates patients based on both entire envelope gene whole coding sequences was evaluated. Herein, 2,298 female 956 male Aedes albopictus at six suspected locations infection August to October grouped into 124 35 pools, respectively, viral...
Jingmen tick virus (JMTV) and the related jingmenvirus-termed Alongshan are recognized as globally emerging human pathogenic tick-borne viruses. These viruses have been detected in various mammals invertebrates, although their natural transmission cycles remain unknown. JMTV a novel jingmenvirus, tentatively named Takachi (TAKV), now identified during surveillance of Japan. was shown to be distributed across extensive areas Japan has repeatedly at same collection sites over several years,...
Japanese encephalitis virus (JEV) is maintained in an enzootic cycle between swine, water birds, and mosquitoes. JEV has circulated indigenously Asia, with Culex tritaeniorhynchus as the primary vector. In some areas where vector scarce or absent, sporadic cases of have been reported, Aedes japonicus presumed to potential a secondary As one world’s most invasive culicid species, Ae . j carries considerable health risk for spreading diseases wider areas, including Europe North America. Thus,...
Abstract Oz virus is a novel thogotovirus isolated from ticks that causes lethal infection in mice. We conducted serosurveillance of among humans and wild mammals Japan using virus-neutralization tests ELISAs. Results showed may be naturally infecting other mammalian hosts.
Several species of birds in Minami Daito Island, an oceanic island located the far south from main islands Japan, were found to be infected with avian Plasmodium. However, no vector malaria this have been revealed yet. To speculate potential vectors, we collected mosquitoes there and investigated using a PCR procedure whether harbor or not. Totally 1,264 including 9 during March 2006 February 2007. The stored every species, sampled date location for DNA extraction. Fifteen out 399 samples...
To evaluate the vectorial capacity of mosquitoes for viruses in Japan, host-feeding habits were analyzed by sequencing polymerase chain reaction-amplified fragments cytochrome b and 16S ribosomal RNA regions mitochondrial DNA 516 15 species from seven genera that collected residential areas during 2003–2006. Culex pipiens L. Aedes albopictus Skuse most commonly urban suburban areas. Anautogenous pallens Coquillett was distinguished autogenous Cx. form molestus Forskal using a reaction-based...
Among members of the order Mononegavirales, RNA splicing events have been found only in family Bornaviridae. Here, we report that a new rhabdovirus isolated from mosquito Culex tritaeniorhynchus replicates nuclei infected cells and requires for viral mRNA maturation. The virus, designated (CTRV), shares similar genome organization with other rhabdoviruses, except presence putative intron coding region L protein. Molecular phylogenetic studies indicated CTRV belongs to Rhabdoviridae, but it...
Entomological surveillance is one of the tools used in monitoring and controlling vector-borne diseases. However, use entomological for arboviral infection vector control often dependent on finding infected individuals. Although this method may suffice highly endemic areas, it not as effective spread diseases low non-endemic areas. In study, we examined efficiency using markers to assess status risk arbovirus Ghana, which considered a country, by combining mosquito with virus isolation...