A5105518195- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Renal cell carcinoma treatment
- Pancreatic and Hepatic Oncology Research
- Liver Disease Diagnosis and Treatment
- Genetic and Kidney Cyst Diseases
- Tuberous Sclerosis Complex Research
- Pancreatitis Pathology and Treatment
- IgG4-Related and Inflammatory Diseases
- Epigenetics and DNA Methylation
- Lung Cancer Treatments and Mutations
- Ovarian cancer diagnosis and treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Liver physiology and pathology
- Hepatitis B Virus Studies
- Neuroendocrine Tumor Research Advances
- Fibroblast Growth Factor Research
- T-cell and B-cell Immunology
- Congenital heart defects research
- Liver Diseases and Immunity
- Intraperitoneal and Appendiceal Malignancies
- Parvovirus B19 Infection Studies
- Cancer Mechanisms and Therapy
Eastern Hepatobiliary Surgery Hospital
2011-2023
Second Military Medical University
2012-2023
University of Freiburg
2022
Weihai Municipal Hospital
2017
Hebei North University
2017
Shantou Central Hospital
2009
Cedars-Sinai Medical Center
2007
First Affiliated Hospital of Zhengzhou University
2006
National Institute of Advanced Industrial Science and Technology
2003
Nippon Zoki (Japan)
1993
Genome-wide association studies (GWAS) have recently identified KIF1B as susceptibility locus for hepatitis B virus (HBV)–related hepatocellular carcinoma (HCC). To further identify novel loci associated with HBV–related HCC and replicate the previously reported association, we performed a large three-stage GWAS in Han Chinese population. 523,663 autosomal SNPs 1,538 HBV–positive patients 1,465 chronic HBV carriers were genotyped discovery stage. Top candidate initial validation samples of...
Mouse embryonic stem-derived cells were recently shown to differentiate into endothelial and smooth muscle cells. In the present study, we investigated whether human umbilical vein endothelium-derived retain potential Examination of biochemical markers, including basic calponin, SM22α, prostaglandin E synthase, von Willebrand factor, PECAM-1, as well cell contractility, showed that whereas cultured with fibroblast growth factor can be characterized cells, when deprived a significant fraction...
Hepatic inflammatory pseudotumors (HIPT) are rare benign neoplasms with unknown etiology and a great potential for mimicry, challenging diagnostics, treatment features. The aim of the study was to retrospectively analyze imaging, pathological, clinical features HIPT in our large cohort patients order increase understanding suggest scoring system approaches. Retrospective analyzed 114 cases recorded from July 2006 2012, when surgery performed. Data were compared chi-square test. In...
In Brief Objective: To report our experience on the safety and efficacy of hepatic resection under selective vascular exclusion (SHVE). Methods: SHVE was used in 246 consecutive patients undergoing major or complex liver center. Preoperative demographic clinical data, details surgical procedure, pathologic diagnosis, postoperative course, complications were collected prospectively. Results: From January 2000 to July 2007, resections performed patients; total SHVE, right partial left 145, 54,...
Bile duct hamartoma (BDH) is a rare liver disease with rising incidence in recent years. A retrospective study on BDH patients between June 2007 and December 2015 was conducted. All the medical records, including clinical, imaging pathological characteristics, were retrieved. Follow‑up data obtained by telephone communication. The majority of had no symptoms laboratory tests normal. appearance ultrasound examination variable. lesion exhibited low density plain computed tomography enhancement...
Hepatocellular carcinoma (HCC) occurring in pregnancy is quite rare. The prognosis usually poor because of a delay diagnosis. Reported cases HCC are largely isolated with no large experience. Thus the effect on patients and risk factors developing not well documented. Our aim was to review our experience management four young pregnant women HCC.Laboratory tests were performed before surgery. We analyzed effects age, hepatitis B surface antigens status, cirrhosis at presentation, gestational...
Abstract Interplay between non-cancerous cells (immune, fibroblasts, mesenchymal stromal (MSC), and endothelial (EC)) has been identified as vital in driving tumor progression. As studying such interactions vivo is challenging, ex systems that can recapitulate scenarios aid unraveling the factors impacting tumorigenesis metastasis. Using synthetic microenvironment mimics (STEMs)—a spheroid system composed of breast cancer (BCC) with defined human MSC EC fractions, here we show organization...
Background Most liver resections require clamping of the hepatic pedicle (Pringle maneuver) to avoid excessive blood loss. But Pringle maneuver can not control backflow bleeding vein. Resection tumors involving veins may cause massive hemorrhage or air embolism from injuries veins. Although total vascular exclusion prevent effectively, it also result in systemic hemodynamic disturbance because inferior vena cava being clamped. Hepatic venous occlusion, a new technique, inflow and outflow...
Abstract Background Both surgery and external‐beam radiotherapy are effective treatments for hepatocellular carcinoma (HCC) patients with inferior vena cava/right atrium (IVC/RA) tumor thrombi. At present, it is not clear which modality more suitable. We therefore compared outcomes between these patients. Methods retrospectively reviewed 108 HCC IVC/RA thrombi who were referred ( n = 51) 57) at three institutions. Different surgical methods selected according to the classification of...
Double primary liver cancer (DPLC) is a special type of clinical situation. As such, detailed analysis the surgical management and prognosis patients with DPLC lacking. The objective current study was to define outcome undergoing surgery for at major hepatobiliary center. A total 87 treated by resection Eastern Hepatobiliary Surgery Hospital from January 1st, 2007 October 31st, 2013 who had demonstrated final pathological diagnosis were identified. Among these, 50 complete prognostic data....