Senthil Nathan

ORCID: 0000-0003-2179-4957
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About
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Research Areas
  • Prostate Cancer Diagnosis and Treatment
  • Prostate Cancer Treatment and Research
  • Bladder and Urothelial Cancer Treatments
  • Urological Disorders and Treatments
  • Ureteral procedures and complications
  • Surgical Simulation and Training
  • Urinary Bladder and Prostate Research
  • Urologic and reproductive health conditions
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pelvic floor disorders treatments
  • Renal and Vascular Pathologies
  • Advanced Radiotherapy Techniques
  • Renal cell carcinoma treatment
  • Pediatric Urology and Nephrology Studies
  • Urinary and Genital Oncology Studies
  • Colorectal Cancer Surgical Treatments
  • Anatomy and Medical Technology
  • Sexual function and dysfunction studies
  • Cardiac Valve Diseases and Treatments
  • Peripheral Nerve Disorders
  • Kidney Stones and Urolithiasis Treatments
  • COVID-19 and healthcare impacts
  • Botulinum Toxin and Related Neurological Disorders
  • Clinical practice guidelines implementation
  • Anesthesia and Pain Management

University College London
2015-2024

University College London Hospitals NHS Foundation Trust
2016-2024

Cleveland Clinic London
2024

Surgical Innovations (United Kingdom)
2024

University College Hospital
2013-2023

Ragas Dental College & Hospital
2023

University College Hospital at Westmoreland Street
2020-2022

Royal Free London NHS Foundation Trust
2021

Hadassah Medical Center
2021

Royal London Hospital
2019-2021

Robot-assisted radical cystectomy is being performed with increasing frequency, but it unclear whether total intracorporeal surgery improves recovery compared open for bladder cancer.

10.1001/jama.2022.7393 article EN JAMA 2022-05-15

To assess the cumulative effect of an enhanced recovery after surgery (ERAS) pathway and minimally invasive robot-assisted radical cystectomy with intracorporeal urinary diversion (iRARC) in comparison open (ORC) on length hospital stay (LOS) peri-operative outcomes.Between February 2009 October 2017, 304 cases were performed at a single institution (ORC, n = 54; [RARC], 250). Data prospectively collected. We identified 45 consecutive ORC without ERAS before commencement RARC programme...

10.1111/bju.14073 article EN BJU International 2017-11-10

Objective To describe a robot-assisted intracorporeal pyramid neobladder reconstruction technique and report operative perioperative metrics, postoperative upper tract imaging, functional outcomes, oncological outcomes. Patients Methods In all, 20 patients (19 male one female) with mean (sd; range) age of 57.2 (12.4; 31.0–78.2) years underwent radical cystectomy (RARC). Most cases were ≤pT1 (17 patients) the remaining three had muscle-invasive bladder cancer (MIBC) at RARC histopathology....

10.1111/bju.13189 article EN BJU International 2015-06-01

No AccessJournal of UrologyAdult Urology: Voiding Dysfunction1 Nov 2005EFFECTS OF BOTULINUM TOXIN B ON REFRACTORY DETRUSOR OVERACTIVITY: A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, CROSSOVER TRIAL M. GHEI, B.H. MARAJ, R. MILLER, S. NATHAN, C. O'SULLIVAN, C.J. FOWLER, P.J.R. SHAH, and J. MALONE-LEE GHEIM. GHEI , MARAJB.H. MARAJ MILLERR. MILLER NATHANS. NATHAN O'SULLIVANC. O'SULLIVAN FOWLERC.J. FOWLER SHAHP.J.R. SHAH MALONE-LEEJ. View All Author...

10.1097/01.ju.0000177477.83991.88 article EN The Journal of Urology 2005-10-07

Objectives To test the feasibility of randomisation to radical prostatectomy (RP) plus pelvic lymphadenectomy in addition standard‐of‐care (SOC) systemic therapy men with newly diagnosed oligo‐metastatic prostate cancer. Patients and Methods A prospective, randomised, non‐blinded, clinical trial an embedded QuinteT Recruitment Intervention (QRI) optimise recruitment was conducted nine nationwide tertiary care centres undertaking high‐volume robotic surgery. We aimed randomise 50 synchronous...

10.1111/bju.15669 article EN BJU International 2021-12-08

Background: The accuracy of multi-parametric MRI (mpMRI) in the pre-operative staging prostate cancer (PCa) remains controversial. Objective: purpose this study was to evaluate ability mpMRI accurately predict PCa extra-prostatic extension (EPE) on a side-specific basis using risk-stratified 5-point Likert scale. This also aimed assess influence scan quality diagnostic accuracy. Patients and Methods: We included 124 men who underwent robot-assisted RP (RARP) as part NeuroSAFE PROOF at our...

10.3390/diagnostics12051057 article EN cc-by Diagnostics 2022-04-23

Objectives To report on the methods, peri‐operative outcomes and histopathological concordance between frozen final section from NeuroSAFE PROOF feasibility study (NCT03317990). Patients Methods Between May 2018 March 2019, 49 patients at two UK centres underwent robot‐assisted radical prostatectomy (RARP). Twenty‐five patient were randomized to RARP (intervention arm) 24 standard (control arm). Frozen was compared paraffin margin assessment in 25 arm. Operation timings complications...

10.1111/bju.15256 article EN cc-by BJU International 2020-12-04

Salvage robot-assisted radical prostatectomy (sRARP) is a potential treatment option for locally recurrent prostate cancer (PCa) after nonsurgical primary treatment. There are minimal data comparing outcomes between propensity-matched sRARP and (RARP).The objective to compare perioperative, oncological, functional of with RARP, the secondary whole focal gland therapy.A 1:1 comparison was carried out 135 cases RARP from cohort 3852 consecutive patients high-volume tertiary...

10.1016/j.euros.2021.03.003 article EN cc-by-nc-nd European Urology Open Science 2021-03-23

We describe the pathological characteristics of recurrence following high intensity focused ultrasound partial ablation in men treated with salvage robot-assisted radical prostatectomy. assessed sensitivity magnetic resonance imaging before prostatectomy these men.A total 35 underwent after from 2012 to 2018. compared clinicopathological and histopathology on infield recurrence, out field disease, positive surgical margins prostatectomy.Before 55.9% had multifocal disease 47.1% Gleason 3 +...

10.1097/ju.0000000000000135 article EN The Journal of Urology 2019-02-04
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