- Spine and Intervertebral Disc Pathology
- Lung Cancer Research Studies
- Medical Imaging and Analysis
- Acupuncture Treatment Research Studies
- Glioma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Metastasis and carcinoma case studies
- Pain Mechanisms and Treatments
- Cancer-related molecular mechanisms research
- Artificial Intelligence in Healthcare and Education
- Thyroid and Parathyroid Surgery
- Gallbladder and Bile Duct Disorders
- Brain Metastases and Treatment
- Pancreatic and Hepatic Oncology Research
- Spinal Hematomas and Complications
- Gastrointestinal Tumor Research and Treatment
- Vascular Malformations and Hemangiomas
- Microbial Natural Products and Biosynthesis
- Gastric Cancer Management and Outcomes
- Healthcare and Venom Research
- Breast Implant and Reconstruction
- Flavonoids in Medical Research
- Management of metastatic bone disease
Beijing Satellite Navigation Center
2024
Beijing University of Chinese Medicine
2024
Sun Yat-sen University
2023-2024
Fujian Medical University
2020-2023
Weatherford College
2023
Gannan Medical University
2023
174th hospital of the People's Liberation Army
2023
Yichun University
2023
Military Hospital
2023
Fujian Women and Children Hospital
2023
Background The demand for healthcare is increasing globally, with notable disparities in access to resources, especially Asia, Africa, and Latin America. rapid development of Artificial Intelligence (AI) technologies, such as OpenAI’s ChatGPT, has shown promise revolutionizing healthcare. However, potential challenges, including the need specialized medical training, privacy concerns, language bias, require attention. Methods To assess applicability limitations ChatGPT Chinese English...
Abstract Background Constipation is one of the most common gastrointestinal complaints with a highly prevalent and often chronic functional disorder affecting health-related quality life. The aim present study was to evaluate effects Salecan on fecal output small intestinal transit in normal two models drug-induced constipation mice. Methods ICR mice were administrated intragastrically (i.g.) by gavage 100, 200 300 mg/kg body weight (BW) while control received saline. constipated induced...
Seven new quinazoline-containing indole alkaloids (1-7) named aspertoryadins A-G, along with nine known ones (8-16), were isolated from the marine-derived fungus Aspergillus sp. HNMF114 bivalve mollusk Sanguinolaria chinensis. The structures of compounds elucidated spectroscopic data, X-ray diffraction analysis, ECD spectra and calculations. Compound 1 bears an aminosulfonyl group in structure, which is rarely encountered natural products. Compounds 6, 7, 13 exhibited quorum sensing...
Abstract Deflectometry is a non-contact and rapid detection method with high sensitivity, which can be utilized in the areas of three-dimensional (3D) reconstruction, surface quality detection, defect location. It has important applications automotive industry, optical parts manufacturing, other fields. Classical deflectometry methods require integration slope data to reconstruct absolute shape. However, procedure error-prone due accumulation random errors into large shape deviations,...
Sturgeons are considered as living fossils and have very high evolutionary, economical conservation values. The multiploidy of sturgeon that has been caused by chromosome duplication may lead to the emergence new microRNAs (miRNAs) involved in ploidy physiological processes. In present study, we performed first miRNAs analysis RNA-seq high-throughput sequencing combined with expression assay microarray real-time PCR, aimed discover sturgeon-specific miRNAs, confirm expressed pattern...
Purpose: This study aimed to investigate changes in metabolomic expression the spinal dorsal horn (SDH) and thalamus during a Tuina session, aiming elucidate mechanism of immediate analgesia. Methods: The rats were randomly divided into three groups: Sham group, Model group. A minor chronic constriction injury (minor CCI) model was established both group therapeutic effect determined using mechanical withdrawal threshold (MWT) thermal latency (TWL) tests. Differential metabolites SDH...
Tuina, as an external treatment method of traditional Chinese medicine, has been proven to have analgesic effect on peripheral neuropathic pain (pNP) in clinical and basic research. However, the optimal time point for tuina may vary according different injury sensations, affecting exploration initiation mechanism analgesia. The research used minor chronic constriction (minor CCI) model rats simulate pNP intelligent manipulation simulator three methods (point-pressing, plucking, kneading)...
The vascularly perfused rat intestine and liver preparations were used to examine the effect of flow (8 10 ml/min) on sequential metabolism 4-methylumbelliferone (4MU), which forms primarily glucuronide conjugate (4MUG) in sulfate (4MUS) at low input concentrations 4MU. In this system, a constant tracer concentration [3H]4MU was delivered systemically 8 or ml/min small preparation; portal venous outflow perfusate collected steady state, reoxygenated tum preparation from second donor....
To summarize the experience in peri-operative treatment of giant nodular goiter.A total 123 patients with goiter sized 6~20 cm were admitted into our hospital from 1990 to 2011 and clinical data retrospectively analyzed. These underwent or subtotal thyroidectomy.All surgical intervention. Unilateral thyroidectomy was performed 40 patients, unilateral 1 patient, bilateral 79 thyroidectomy, removal entire isthmus contralateral 3 patients. Nodular pathologically proven post-operatively. No...
We present a valid and reproducible nomogram that combined the TNM stage as well Ki-67 index carcinoembryonic antigen levels; may be an indispensable tool to help predict individualized risks of death clinicians manage patients with gastric neuroendocrine carcinoma.To analyze long-term outcomes grade 3 GNEC who underwent curative surgery investigated whether combination (CEA) levels can prognosis carcinoma (GNEC) constructed patient survival.In training cohort, data were collected from 405...
OBJECTIVE CT and MRI are synergistic in the information provided for neurosurgical planning. While obtaining both types of images lends unique data from each, doing so adds to cost exposes patients additional ionizing radiation after has been performed. Cross-modal synthesis high-resolution sequences offers an appealing solution. The authors therefore sought develop a deep learning conditional generative adversarial network (cGAN) which performs this synthesis. METHODS Preoperative paired...
Acne is the eighth most common disease worldwide. Disease burden of acne such as anxiety, reduced self-esteem, and facial scarring lowers life quality patients. Isotretinoin potent treatment for moderate-severe acne. However, adverse events isotretinoin especially teratogenicity limit its use. This study aims at investigating therapeutical mechanisms using bioinformatics analysis. Differentially expressed genes (DEGs) were filtered from microarray datasets GSE10432, GSE10433, GSE11792....
<b><i>Purpose:</i></b> To evaluate whether the European Neuroendocrine Tumor Society (ENETS) system or 8th American Joint Committee on Cancer (AJCC) staging manual are suitable for gastric neuroendocrine carcinomas and/or mixed adenoneuroendocrine (G-NECs/MANECs). <b><i>Methods:</i></b> Patients in a multicentric series with G-NEC/MANEC who underwent curative-intent surgical resection primary tumor were included. An optimal was proposed base...
The aim of the study was to compare application value percutaneous transforaminal endoscopic discectomy (PTED) and microendoscopic (MED) in treatment lumbar disc herniation (LDH). From January 2017 July 2018, 108 LDH patients undergoing surgical our hospital were collected divided into PTED group (treated with PTED, n=50) MED MED, n=58). operation parameter index level, complications, recurrence pain score (VAS), Oswestry disability (ODI) Japanese Orthopaedic Association Scale (JOA) compared...
The human visual pathway starts from the retina, passes through retinogeniculate pathway, optic radiation, and finally connects to primary cortex. Diffusion MRI tractography is only technology that can noninvasively reconstruct pathway. However, complete accurate reconstruction challenging because of skull base environment complex fiber geometries. Specifically, nerve within cause abnormal diffusion signals. crossing fanning fibers at chiasm, a sharp turn Meyer's loop contribute geometries A...
To conclude of the technical notes percutaneous transforaminal endoscope-assisted lumbar interbody fusion (PT-Endo-LIF), and to investigate its safety efficacy for treatment degenerative disease.Twenty-four patients were treated by PT-Endo-LIF combined with posterior pedicle screws fixation from October 2017 April 2018. There 16 males 8 females, ranging in age 39 72 years old, a mean (59.6±9.5) old. 15 cases diagnosed intervertebral disc herniation disc, other 9 as low level...